Navigation Links
Lowering Blood Pressure Improves Brain Hemorrhage Outcomes
Date:4/4/2008

Aggressive action is safe and may cut risk of disability, death, study finds

FRIDAY, April 4 (HealthDay News) -- Intravenous treatment to drastically lower the blood pressure of people who've just suffered bleeding in the brain may improve their prognosis, a pilot study suggests.

Intracranial hemorrhage often causes a rapid rise in blood pressure, which may contribute to further bleeding and the growth of the hematoma (an area of internal bleeding). This can cause the patient's condition to deteriorate and increase the risk of disability or death, according to background information in the study.

Although it's recommended to lower very high blood pressure as soon as possible in patients with intracranial hemorrhage, there is little evidence on when to start treatment or how much to lower blood pressure. This leads to wide variations in the management of high blood pressure in these patients.

This study compared intensive blood-pressure lowering treatment (target systolic blood pressure 140mm Hg) in 203 patients to the recommended best practice standard strategy (target systolic blood pressure 180 mm Hg) in 201 patients.

Brain scans conducted 24 hours after the start of treatment showed hematoma growth of 13.7 percent in the intensive treatment group, compared with 36.6 percent in the non-intensive group.

There were no differences between the two groups in terms of harmful side effects, rates of death and disability, or quality of life for survivors after 90 days.

"Because intravenous treatment to lower blood pressure is relatively straightforward, is not hazardous, and is of low cost, if applied widely, these effects could translate into major absolute benefits," concluded Dr. Craig Anderson, of the George Institute for International Health in Sydney, Australia, and colleagues.

The study was expected to be published in the May issue of The Lancet Neurology.

In the next phase of the trial, the researchers plan to assess how the intensive blood pressure-lowering treatment affects death and dependency in 2,800 intracranial hemorrhage patients worldwide.

In an accompanying Comment, Dr. Mustapha Ezzeddine, of the University of Minnesota, wrote that the study provides the best evidence to date of the safety of this kind of treatment.

However, many questions remain: Do the results apply to other stroke patients? How early and how long should blood pressure be controlled? Do different drugs have different effects?

The follow-up studies "are likely to answer some of these questions and, more importantly, to detect any effect on outcomes," Ezzeddine wrote.

More information

The MedlinePlus Medical Encyclopedia has more about intracranial hemorrhage.



-- Robert Preidt



SOURCE: The Lancet Neurology, news release, April 4, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Stanford study highlights cost-effective method of lowering heart disease risks
2. Lowering Blood Protein Wont Help Kidney Patients
3. Abbotts Investigational SIMCOR(R) Offers Comparable LDL Lowering to Simvastatin and Significantly Raises HDL and Lowers Triglycerides in Phase III Study
4. Cholesterol-lowering drug linked to sleep disruptions
5. Many Patients Stop Taking Cholesterol-Lowering Drugs
6. Amount of Exercise Key to Lowering Kids Blood Pressure
7. New Type of Cholesterol-Lowering Drug Shows Promise
8. Lowering Co-Pays on Some Drugs Help Fight Chronic Diseases
9. Cholesterol-Lowering Drugs May Ease Irregular Heartbeat
10. Cholesterol-Lowering Statins Tied to Tendon Woes
11. Study shows cholesterol-lowering power of dietitian visits
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... June 27, 2016 , ... A revolution is ... emergency ambulance transport experience for the millions of people who require these medical ... the taxi industry through the use of technology. Now, SmartEMS has put forth ...
(Date:6/26/2016)... ... 26, 2016 , ... PawPaws brand pet supplements owned by Whole ... enhance the health of felines. The formula is all-natural and is made from Chinese ... PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract and ...
(Date:6/25/2016)... ... ... Bruton Memorial Library on June 21 due to a possible lice infestation, as reported by ... lice: the parasite’s ability to live away from a human host, and to infest common ... the event that lice have simply gotten out of control. , As lice are a ...
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of ... recognition of their exemplary accomplishments in worksite health promotion. , The Wellness at Work ... Symposium at the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her ... would lash out at his family verbally and physically. , “When something upset him, he ... he would use it. He would throw rocks at my other children and say he ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- MedSource announced today that it has selected Datatrial,s ... choice.  This latest decision demonstrates MedSource,s commitment to ... by offering a state-of-the-art electronic data capture (EDC) ... the EDC platform of choice in exchange for ... long been a preferred EDC platform by our ...
(Date:6/23/2016)... Research and Markets has announced the addition ... Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), Functionality (Filler, Binder, ... Forecast to 2021" report to their offering. ... excipients market is projected to reach USD 8.1 Billion ... forecast period 2016 to 2021. The ...
(Date:6/23/2016)... June 23, 2016 Research and Markets ... Medical Market Analysis 2016 - Forecast to 2022" report ... The report contains up to date financial data derived from ... of major trends with potential impact on the market during ... market segmentation which comprises of sub markets, regional and country ...
Breaking Medicine Technology: