Navigation Links
Lowering Blood Pressure Improves Brain Hemorrhage Outcomes
Date:4/4/2008

Aggressive action is safe and may cut risk of disability, death, study finds

FRIDAY, April 4 (HealthDay News) -- Intravenous treatment to drastically lower the blood pressure of people who've just suffered bleeding in the brain may improve their prognosis, a pilot study suggests.

Intracranial hemorrhage often causes a rapid rise in blood pressure, which may contribute to further bleeding and the growth of the hematoma (an area of internal bleeding). This can cause the patient's condition to deteriorate and increase the risk of disability or death, according to background information in the study.

Although it's recommended to lower very high blood pressure as soon as possible in patients with intracranial hemorrhage, there is little evidence on when to start treatment or how much to lower blood pressure. This leads to wide variations in the management of high blood pressure in these patients.

This study compared intensive blood-pressure lowering treatment (target systolic blood pressure 140mm Hg) in 203 patients to the recommended best practice standard strategy (target systolic blood pressure 180 mm Hg) in 201 patients.

Brain scans conducted 24 hours after the start of treatment showed hematoma growth of 13.7 percent in the intensive treatment group, compared with 36.6 percent in the non-intensive group.

There were no differences between the two groups in terms of harmful side effects, rates of death and disability, or quality of life for survivors after 90 days.

"Because intravenous treatment to lower blood pressure is relatively straightforward, is not hazardous, and is of low cost, if applied widely, these effects could translate into major absolute benefits," concluded Dr. Craig Anderson, of the George Institute for International Health in Sydney, Australia, and colleagues.

The study was expected to be published in the May issue of The Lancet Neurology.

In the next phase of the trial, the researchers plan to assess how the intensive blood pressure-lowering treatment affects death and dependency in 2,800 intracranial hemorrhage patients worldwide.

In an accompanying Comment, Dr. Mustapha Ezzeddine, of the University of Minnesota, wrote that the study provides the best evidence to date of the safety of this kind of treatment.

However, many questions remain: Do the results apply to other stroke patients? How early and how long should blood pressure be controlled? Do different drugs have different effects?

The follow-up studies "are likely to answer some of these questions and, more importantly, to detect any effect on outcomes," Ezzeddine wrote.

More information

The MedlinePlus Medical Encyclopedia has more about intracranial hemorrhage.



-- Robert Preidt



SOURCE: The Lancet Neurology, news release, April 4, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Stanford study highlights cost-effective method of lowering heart disease risks
2. Lowering Blood Protein Wont Help Kidney Patients
3. Abbotts Investigational SIMCOR(R) Offers Comparable LDL Lowering to Simvastatin and Significantly Raises HDL and Lowers Triglycerides in Phase III Study
4. Cholesterol-lowering drug linked to sleep disruptions
5. Many Patients Stop Taking Cholesterol-Lowering Drugs
6. Amount of Exercise Key to Lowering Kids Blood Pressure
7. New Type of Cholesterol-Lowering Drug Shows Promise
8. Lowering Co-Pays on Some Drugs Help Fight Chronic Diseases
9. Cholesterol-Lowering Drugs May Ease Irregular Heartbeat
10. Cholesterol-Lowering Statins Tied to Tendon Woes
11. Study shows cholesterol-lowering power of dietitian visits
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/2/2016)... ... , ... Dr. Philip Shindler, dentist in Agoura Hills , now offers ... many necessary dental treatments could require multiple appointments to complete. This could mean taking ... time. Not only could this be inconvenient, but it could also be overwhelmingly unpleasant ...
(Date:5/2/2016)... Rhinebeck, NY (PRWEB) , ... May 02, 2016 , ... ... Valley, reopened for its 2016 guest season which runs through October. Omega is offering ... talks . , “There has never been such widespread interest in or ...
(Date:5/2/2016)... ... May 02, 2016 , ... Visceral ... organs, such as the kidneys, liver and pancreas. If not properly addressed, visceral ... board-certified physician in Internal Medicine, Medical Oncology and Palliative Care, warns against the ...
(Date:5/2/2016)... ... May 02, 2016 , ... Pregnancy Awareness Month offers a great time to ... , “If you are ready to have a baby, it’s best to get started ... Babies is your Personal Conception & Pregnancy Organizer, written for women who plan on ...
(Date:5/2/2016)... ... 02, 2016 , ... Consultative health care market research firm ... and Duane Reed, VP of business development of AJMC Strategic Solutions, will be ... (PBIRG) General Meeting from May 15-17 at the Boca Raton Resort & ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... , April 28, 2016  ValGenesis, Inc., ... Management Solutions (VLMS) today announced that a ... for sufferers of chronic kidney failure has ... manage their corporate validation process. The global ... software solution to manage their validation processes ...
(Date:4/27/2016)... , Schweiz, April 27, 2016 ... Sachs CEO Forums in Zürich gab Strekin ... führenden Wirkstoffkandidaten STR001 zur Erhaltung des Resthörvermögens ... wurde, bekannt. Für die umfassende Phase-II-Doppelblindstudie mit ... Frankreich angeworben. STR001 wird während der Operation ...
(Date:4/27/2016)... , April 27, 2016 ... titled, "Skincare Devices Market - Global Industry Analysis, Size, ... to the report, the global skincare devices market was ... anticipated to expand at a CAGR of 10.1% from ... 2023. Browse the full Skincare Devices Market (Treatment ...
Breaking Medicine Technology: