Navigation Links
Lower-dose fractionated stereotactic radiotherapy results in better hearing preservation
Date:12/17/2008

(PHILADELPHIA) Researchers at Thomas Jefferson University have found that a lower dose of fractionated stereotactic radiotherapy for acoustic neuromas results in better hearing preservation and has the same tumor local control rate as a higher dose of therapy. The study appeared online in the International Journal of Radiation Oncology*Biology*Physics.

"We previously had not determined the optimal dose of fractionated stereotactic radiotherapy for acoustic neuromas," said David W. Andrews, M.D., professor and vice-chairman of the Department of Neurological Surgery at Jefferson Medical College of Thomas Jefferson University, and the lead author. "This study was designed to compare the hearing preservation between the two doses. The lower-dose treatment resulted in a 100 percent tumor control rate, with the advantage of better hearing preservation."

Between 1994 and 2007, 101 patients with serviceable hearing were treated at Jefferson with fractionated stereotactic radiotherapy (FSR). Dr. Andrews and colleagues analyzed 89 patients within that cohort who had complete audiometric data available. Forty-three patients had received the high-dose of 50.4 Gruyere (Gy). Forty-six patients received the low-dose of 46.8 Gy.

The tumor local control rates were 100% for both the lower-dose cohort and the higher-dose cohort. The pure tone average was 33 decibels (dB) in the lower-dose cohort, which was significantly better than the 40 dB pure tone average in the high-dose cohort. The actuarial hearing preservation rate was also longer in the lower-dose cohort: 165 weeks vs. 79 weeks.

"This is a potentially practice-changing finding," Dr. Andrews said. "We are now working to design a study to directly compare FSR with other treatment options, including stereotactic single fraction radiosurgery."

According to Dr. Andrews, the tumor control rates for FSR are comparable to those of stereotactic single fraction radiosurgery, a
'/>"/>

Contact: Emily Shafer
emily.shafer@jefferson.edu
215-955-5291
Thomas Jefferson University
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. Grupo IMO Hosts Symposium on Use of TomoTherapy for Stereotactic Radiosurgery and Stereotactic Body Radiation Procedures : Experts Detail HiArt Platform Advantages for Treatment of Brain, Lung, Pancreatic and Metastatic Cancers
2. BrainLAB Announces 510(k) FDA Clearance of Monte Carlo Dose Engine for Stereotactic Radiosurgery and Radiation Therapy
3. IAME Goes Live With New Stereotactic Breast Program
4. ESF workshop makes major advance in cancer radiotherapy
5. Central California Doctors Now Using Fast RapidArc(TM) Radiotherapy Technology to Battle Cancer
6. Cancer Patients in Southeastern Florida Now Benefiting From RapidArc(TM) Radiotherapy Treatments
7. Clinicians in Netherlands Treat Lung Cancer Patients Using New RapidArc Radiotherapy Technology from Varian Medical Systems
8. Varian Medical Systems Signs Collaboration Agreement to Bring Advanced Radiotherapy Equipment to Indonesia
9. Decatur Memorial Hospital Becomes First in Illinois to Treat Cancer Patients With RapidArc(TM) Radiotherapy Technology
10. Modulated radiotherapy can cut treatment time for cancer of the rectum without increasing toxicity
11. Elekta Launches Web-based Virtual Clinic, Offers Better Understanding of Radiotherapy Solutions for the Treatment of Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2009)... -- CareFusion Corporation (NYSE: CFN ) announced ... mini-tender offer by TRC Capital Corporation (TRC) to purchase ... representing approximately 1.8 percent of the shares of common ... is 4.62 percent below the share closing price of ... full trading day prior to the offer. CareFusion also ...
(Date:12/17/2009)... elder care expert announces the release of her new book “Priceless ... is a contributing author and the primary compiler of stories for ... Now released in paperback, Priceless Caregiving can be ordered through ... ... St. Louis, MO (PRWEB) December 17, 2009 -- Valerie VanBooven RN ...
(Date:12/17/2009)... portrait of the nearly one-in-three American adults who serve as a ... ... 2009 -- The National Alliance on Mental Illness (NAMI) praises a ... a revealing portrait of the nearly one-in-three American adults who serve ... interviews with 1,480 caregivers chosen at random and offers a national ...
(Date:12/17/2009)... MediNiche provide alternative natural relief prior to considering drugs. ... ... 17, 2009 -- D-Psoria products are the first ... with severe skin conditions . Developed by Astrel ... MediNiche Pharmaceuticals, St. Louis, Missouri., , ,D-Psoria products ...
(Date:12/17/2009)... Healthcare Cost/Risk Analysis reports, activity measures and outcomes reporting to ... toward reduced claim costs and positive return on investment over ... ... Jacksonville, FL (PRWEB) December 17, 2009 -- ... in clinical/claims based cost risk analysis along with personalized nurse ...
Breaking Medicine News(10 mins):Health News:CareFusion Recommends Rejection of Mini-Tender Offer by TRC Capital 2Health News:Valerie VanBooven RN BSN Announces the Release of her 3rd Book Celebrating Caregivers and Families 2Health News:Valerie VanBooven RN BSN Announces the Release of her 3rd Book Celebrating Caregivers and Families 3Health News:NAMI Applauds New Report on Caregiving 2Health News:NAMI Applauds New Report on Caregiving 3Health News:Introducing D-Psoria, the First Cosmeceutical Products for the Relief of the Redness, Scaling, and Flaking of Severely Damaged Skin 2Health News:Introducing D-Psoria, the First Cosmeceutical Products for the Relief of the Redness, Scaling, and Flaking of Severely Damaged Skin 3Health News:Introducing D-Psoria, the First Cosmeceutical Products for the Relief of the Redness, Scaling, and Flaking of Severely Damaged Skin 4Health News:Baptist Health System Selects HealthScreen Disease Management for Employee Health Management Services 2
... study appearing online on February 8 in advance of ... of Clinical Investigation//, Daniel Weinberger and colleagues from the ... encodes DARPP-32 exhibits genetic variation. ,Several neurological ... are associated with changes in the brain that affect ...
... According to a study conducted by British researchers, breast fed ... fed counterparts//. This once again goes on to prove the ... conducted by Institute of Child Health in London among 262 ... In this group, 184 children have been bottle-fed with formula ...
... there is a fine line between genius and madness and this may ... Mental health workers have always been baffled by one of the most ... affect one in 100 persons and causes disordered ideas, beliefs, and experiences. ... 25 to 35. , Scientists working for U.S National ...
... to an article recently published in the journal Blood, ... risk of diabetes and hypertension. ,An allogeneic ... types of cancers, particularly leukemia and lymphoma. The process ... use of high-dose chemotherapy or total body irradiation. These ...
... Duke University Medical Center researchers have created// a three-dimensional ... physicians to repair damaged joints with the patient's own ... successful, the scaffold could be used in clinical trials ... graduate student in the Orthopedic Bioengineering Laboratory who designed ...
... Technology are one step closer to developing a ... most common sexually-transmitted disease, Chlamydia. ... a funding boost of more than $300,000 to ... developing a vaccine specifically targeting adolescent women. ...
Other Medicine News:Health News:Madness- the Genius Connection 2Health News:Allogeneic Stem Cell Transplants Linked With Risk for Diabetes and Hypertension 2Health News:Woven Cartilage 2Health News:Chlamydia Vaccine a Step Closer to Reality 2
(Date:12/16/2009)... -- BioSpecifics Technologies Corp. (Nasdaq: BSTC ), ... products, today announced top-line efficacy and safety results ... for the treatment of Peyronie,s disease. Peyronie,s disease ... on the shaft of the penis, which can ... or impossible in advanced cases. The Phase 2b ...
(Date:12/16/2009)... Dec. 16 Vivakor, Inc. (OTC ... Development agreement with Baker Consulting out of ... Kyouko Group, Inc. out of South Florida. ... Vivakor to assist with business development, financing ... reported acquisition strategy. Specifically, Baker Consulting is ...
(Date:12/16/2009)... Ill., Dec. 16 Naurex Inc., a ... depression and other CNS disorders based on its ... it has initiated a Phase I clinical trial ... dosed the first subjects in the study. ... selective modulator of the NMDA receptor, is initially ...
Breaking Medicine Technology:BioSpecifics Technologies Corp. Announces Top-Line Phase 2b Results for XIAFLEX(TM) for Treatment of Peyronie's Disease 2BioSpecifics Technologies Corp. Announces Top-Line Phase 2b Results for XIAFLEX(TM) for Treatment of Peyronie's Disease 3BioSpecifics Technologies Corp. Announces Top-Line Phase 2b Results for XIAFLEX(TM) for Treatment of Peyronie's Disease 4Vivakor Signs Business Development Agreement With Baker Consulting 2Naurex Inc. Initiates Phase I Clinical Trial of its Novel Mechanism NMDA Modulator GLYX-13 in Treatment-Resistant Depression 2Naurex Inc. Initiates Phase I Clinical Trial of its Novel Mechanism NMDA Modulator GLYX-13 in Treatment-Resistant Depression 3Pelosi 3A Food Safety Act Will Protect Lives and Prevent Illness 53308 1Regence BlueShield of Idaho Announces Executive Changes 53303 1Regence BlueShield of Idaho Announces Executive Changes 53303 2Regence BlueShield of Idaho Announces Executive Changes 53303 3Abbott Testifies Before U S Congress on Role of Private Sector in Advancing Science Education 53299 1Abbott Testifies Before U S Congress on Role of Private Sector in Advancing Science Education 53299 2Abbott Testifies Before U S Congress on Role of Private Sector in Advancing Science Education 53299 3
... test device is intended for ... IgG and IgM antibodies to ... The test is used as ... of Dengue viral infection and ...
RapidStrep A test is a qualitative test that detects group A,streptococcal antigen. The test is a rapid, in vitro assay. It is,intended for professional use to help diagnose Strep A,infection i...
The IntraStent DoubleStrut Biliary Stent represents a completely new direction in stent design. The combination of parallel struts and unique cell geometry provide unparalleled performance....
Inquire...
Medicine Products: