Navigation Links
Low-protein diet slows Alzheimer's in mice
Date:2/14/2013

Mice with many of the pathologies of Alzheimer's Disease showed fewer signs of the disease when given a protein-restricted diet supplemented with specific amino acids every other week for four months.

Mice at advanced stages of the disease were put on the new diet. They showed improved cognitive abilities over their non-dieting peers when their memory was tested using mazes. In addition, fewer of their neurons contained abnormal levels of a damaged protein, called "tau," which accumulates in the brains of Alzheimer's patients.

Dietary protein is the major dietary regulator of a growth hormone known as IGF-1, which has been associated with aging and diseases in mice and several diseases in older adults.

Upcoming studies by USC Professor Valter Longo, the study's corresponding author, will attempt to determine whether humans respond similarly while simultaneously examining the effects of dietary restrictions on cancer, diabetes and cardiac disease.

"We had previously shown that humans deficient in Growth Hormone receptor and IGF-I displayed reduced incidence of cancer and diabetes. Although the new study is in mice, it raises the possibility that low protein intake and low IGF-I may also protect from age-dependent neurodegeneration," said Longo, who directs the Longevity Institute of the USC Davis School of Gerontology and has a joint appointment the USC Dornsife College of Letters, Arts and Sciences.

Longo worked with Pinchas Cohen, dean of the USC Davis School, as well as USC graduate students Edoardo Parrella, Tom Maxim, Lu Zhang, Junxiang Wan and Min Wei; Francesca Maialetti of the Istituto Superiore di Sanit in Rome; and Luigi Fontana of Washington University in St. Louis.

"Alzheimer's Disease and other forms of neurodegeneration are a major burden on society, and it is a rising priority for this nation to develop new approaches for preventing and treating these conditions, since the frequencies of these
'/>"/>

Contact: Robert Perkins
perkinsr@usc.edu
213-740-9226
University of Southern California
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. Oxygen Therapy Slows Type 1 Diabetes in Mice, Study Says
2. Infection With 2 HIV Strains Slows Disease Progression
3. Mild HIV type slows development of AIDS and makes new preventive treatments possible
4. Mesothelioma drug slows disease progression in patients with an inactive NF2 gene
5. Active lifestyle boosts brain structure and slows Alzheimer’s disease
6. Newly approved oral medication slows rheumatoid arthritis joint damage
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2013)... On a Saturday morning last summer, MSgt. ... watching “The Bourne Legacy” at the White Flint Mall movie ... a typical activity to many couples, it is a pure ... from their everyday reality has become possible through the Military ... | VA. , Life changed for the DesLauriers family on ...
(Date:5/22/2013)... The Muscular Dystrophy Association scored a huge ... annual Charlotte Muscle Team event held May 21 by ... with muscle disease. , "The Charlotte community really ... families,” said MDA Divisional Director Theresa Miller. “From the ... "Buddy" to make their night extra special, to the ...
(Date:5/22/2013)... WEDNESDAY, May 22 (HealthDay News) -- People who endure ... attempt suicide, whether or not they also suffer from ... study. "Clinicians who are seeing patients with certain ... risk of suicide," said study co-author Mark Ilgen, of ... Evaluation Center in Ann Arbor, Mich. "Although undoubtedly ...
(Date:5/22/2013)... Diversity Focus and Handicap This Productions announce ... promotes awareness that physical disabilities do not stop people ... be held Friday, June 14th at 7:30 p.m. at ... Handicap This! can be purchased at http://www.diversityfocus.org . ... to which their mind is handicap accessible. Mike ...
(Date:5/22/2013)... Researchers in genomic health disparities from the University ... University School of Medicine have teamed up to hold ... Eliminate Health Disparities in Genomic Medicine." The theme ... nonprofits, business and government to reduce these disparities. , ... United States, individuals within underserved groups continue to be ...
Breaking Medicine News(10 mins):Health News:Military Family Finds Respite with Easter Seals 2Health News:Military Family Finds Respite with Easter Seals 3Health News:Charlotte Muscle Team Event Raises $300,000 in the Fight Against Muscle Disease 2Health News:Migraine, Chronic Back Pain Tied to Higher Suicide Risk 2Health News:Migraine, Chronic Back Pain Tied to Higher Suicide Risk 3Health News:Handicap This! Comes to Marion, Iowa 2Health News:Why We Can't Wait: Conference to Eliminate Health Disparities in Genomic Medicine 2
... collaboration to address the lack of medical devices designed ... Hospital Medical Center (CCH) in Ohio and Ben-Gurion University ... is to improve health outcomes for children by ensuring ... physiological differences and medical needs. "The project combines ...
... by University of Minnesota researchers could put a stop ... by the bacterium Clostridium difficile . CIPAC Limited, ... to work with the university to advance the technology ... preparations. C. difficile affects several million ...
... found in grocery store produce aisles, shows promise as a ... following a new study at the University of Missouri. MU ... that is stimulated by progestin, a synthetic hormone given to ... the first study to show that apigenin, which can be ...
... , TUESDAY, May 15 (HealthDay News) -- Black and Hispanic ... colorectal polyps, a new study finds. Researchers analyzed data ... older who had a first-time colonoscopy screening at New York-Presbyterian ... and 2010. None of the patients had signs or symptoms ...
... (HealthDay News) -- The lives of more than 740,000 people ... by the U.S. President,s Emergency Plan for AIDS Relief, a ... death from all causes by 16 percent to 20 percent ... found. The researchers said this is the first study to ...
... who undergo radical surgery for prostate cancer may expect ... teaching hospitals with residency programs, and better still if ... new study by Henry Ford Hospital. The study, ... patients throughout the U.S., also found that those with ...
Cached Medicine News:Health News:Ben-Gurion U. and Cincinnati Children's Hospital to develop pediatric-specific medical technologies 2Health News:University of Minnesota startup to treat challenging bacterial infection 2Health News:Breast cancer effectively treated with chemical found in celery, parsley by MU researchers 2Health News:Blacks, Hispanics Have Higher Colon Polyp Risk Than Previously Thought 2Health News:Fewer prostate cancer surgery complications found in teaching hospitals with fellowship programs 2
(Date:5/22/2013)... , May 22, 2013 STEPh, Inc., a ... the launch of their web site ( http://www.stephreports.com ... About STEPh Reports STEPh ... Each STEPh Report assesses the competitive ... projected launch year, company, and specific key issues.  STEPh ...
(Date:5/22/2013)... May 22, 2013   Upsher-Smith Laboratories, ... of its global Phase III clinical trial ... program for the management of epilepsy in ... USL255 is specifically engineered to provide convenient ... blood levels observed with currently available treatment ...
(Date:5/22/2013)... N.J. , May 22, 2013 MEDIFIRST ... opportunity to update shareholders about some recent company developments. ... expand its avenues of communication with shareholders. Integrating social ... launched a Facebook page and will post updates on ... Twitter hashtag is #medifirstusa. Says CEO ...
Breaking Medicine Technology:Scientific and Technical Evaluation of Pharmaceuticals, Inc. [STEPh, Inc.], Launches New Competitive Intelligence Web Site 2Upsher-Smith Successfully Completes Phase III Study Of USL255 (Extended-Release Topiramate) For Adjunctive Treatment Of Epilepsy In Patients With Refractory Partial-Onset Seizures 2Upsher-Smith Successfully Completes Phase III Study Of USL255 (Extended-Release Topiramate) For Adjunctive Treatment Of Epilepsy In Patients With Refractory Partial-Onset Seizures 3Upsher-Smith Successfully Completes Phase III Study Of USL255 (Extended-Release Topiramate) For Adjunctive Treatment Of Epilepsy In Patients With Refractory Partial-Onset Seizures 4Medifirst Solutions, Inc. Announces Update To Shareholders 2
... 30 Transgenomic, Inc. (OTC,Bulletin Board: TBIO), a ... National Cancer Institute had approved a proposal to,perform ... in,the NCI 60 cancer cell line panel., ... warning,signal in several different types of cancer. This ...
... Spherix Incorporated,(Nasdaq: SPEX ) announced today that it ... manufacturer of bulk pharmaceutical ingredients,to supply a portion of ... of the unique sugar as a treatment for Type ... Practice) production batches,of D- tagatose for the Spherix New ...
Cached Medicine Technology:Transgenomic Establishes Collaboration With the National Cancer Institute to Investigate Mitochondrial Genome and Associated Nuclear Genes in Cancer Cell Lines 2Transgenomic Establishes Collaboration With the National Cancer Institute to Investigate Mitochondrial Genome and Associated Nuclear Genes in Cancer Cell Lines 3Spherix D-tagatose to be Supplied by Inalco SpA 2
Stab incision blades color coded for simple and accurate identification...
Smooth, round edges allow for safe manipulation within the eye. 1.1mm wide gradually tapers to .50 mm wide. 45, 1.1mm wide, gradually tapers to .50mm wide....
... has two perforations which enable ... various single or bilateral configurations ... drape has two perforations which ... to various single or bilateral ...
30, 6.0mm from end...
Medicine Products: