Navigation Links
Low potassium linked to high blood pressure
Date:11/8/2008

As a risk factor for high blood pressure, low levels of potassium in the diet may be as important as high levels of sodiumespecially among African Americans, according to research being presented at the American Society of Nephrology's 41st Annual Meeting and Scientific Exposition in Philadelphia, Pennsylvania.

"There has been a lot of publicity about lowering salt or sodium in the diet in order to lower blood pressure, but not enough on increasing dietary potassium," comments lead author Susan Hedayati, MD, of the University of Texas Southwestern Medical Center in Dallas, Texas, and the Dallas VA Medical Center. The new study suggests that low potassium may be a particularly important contributor to high blood pressure among African Americans, and also identifies a gene that may influence potassium's effects on blood pressure.

The researchers analyzed data on approximately 3,300 subjects from the Dallas Heart Study, about half of whom were African American. The results showed that the amount of potassium in urine samples was strongly related to blood pressure. "The lower the potassium in the urine, hence the lower the potassium in the diet, the higher the blood pressure," says Dr. Hedayati. "This effect was even stronger than the effect of sodium on blood pressure."

The relationship between low potassium and high blood pressure remained significant even when age, race, and other cardiovascular risk factorsincluding high cholesterol, diabetes, and smokingwere taken into account.

Previous studies, including the landmark "Dietary Approaches to Stop Hypertension" study (DASH), have linked potassium deficiency to high blood pressure. The new results support this conclusion, and provide important new data on the relationship between potassium and blood pressure in a sample that was 50% African American. "Our study included a high percentage of African-Americans, who are known to consume the lowest amounts of potassium in the diet," according to Dr. Hedayati.

Research performed in the laboratory of Dr. Chou-Long Huang, a co-author of this study, has found evidence that a specific gene, called WNK1, may be responsible for potassium's effects on blood pressure. "We are currently doing more research to test how low potassium in the diet affects blood pressure through the activity of this gene," adds Dr. Hedayati.

The conclusions are limited by the fact that people in the Dallas Heart Study weren't following any specific diet. The researchers are currently performing a study in which participants are on fixed potassium diets while measuring the activity of the WNK1 gene to see if WNK1 is responsible for this phenomenon.

Meanwhile, they urge efforts to increase the amount of potassium in the diet, as well as lowering sodium. "High-potassium foods include fruits such as bananas and citrus fruits and vegetables," says Dr, Hedayati. "Consuming a larger amount of these foods in the diet may lower blood pressure."


'/>"/>

Contact: Shari Leventhal
sleventhal@asn-online.org
American Society of Nephrology
Source:Eurekalert

Related medicine news :

1. A drug-sensitive traffic cop tells potassium channels to get lost
2. Watson Receives FDA Approval of Potassium Chloride Extended-Release Capsules
3. Unilever Unveils Promise(R) SuperShots(R) for Blood Pressure, the First Functional Shot to Increase Daily Potassium Intake to Help Reduce the Risk of High Blood Pressure
4. Pot bellies linked to early signs of cardiovascular disease
5. Diet high in meat, fat and refined grains linked to risk for colon cancer recurrence, death
6. Immune deficiency linked to a type of eye cancer
7. Drop in breast cancer incidence linked to hormone use, not mammograms
8. Clinical depression linked to abnormal emotional brain circuits
9. Air pollution linked to cardiovascular risk indices in healthy young adults
10. High pollution linked to poor lung function growth in children in Mexico City
11. Early Weight Loss in Women Linked to Dementia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... The American Board of ... its next President and Chief Executive Officer, succeeding Dr. James C. Puffer upon his ... July 1, 2018 until Dr. Puffer’s retirement at the end of 2018. Upon assuming ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with clinical associate professor ... prevention of cardiovascular diseases during the 15th Annual Women’s Health Conference. The ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Many families have ... many long-term care insurance companies have a waiver for care if the client has ... period, when the family pays for care, is often waived, so the benefits from ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual ... in Milford, NJ. This free event, sponsored by Global Healthcare Management’s CEO, Jon ... fun run is geared towards children of all ages; it is a non-competitive, non-timed ...
(Date:10/13/2017)... , ... October 13, 2017 , ... ... and Agile Software Development, has been awarded a contract by the Center for ... Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies in a ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... West Pharmaceutical Services, Inc. (NYSE: ... drug administration, today announced that it will release third-quarter ... October 26, 2017, and will follow with a conference ... 9:00 a.m. Eastern Time. To participate on the call, ... ID is 94093362. ...
(Date:10/10/2017)... Oct. 10, 2017  NDS received FDA 510(k) clearance in May ... battery-powered display stand specifically designed for endoscopy environments. An innovative secondary ... a clinical solution to support the improvement of patient outcomes, procedural ... ... ...
(Date:10/4/2017)... Mass. , Oct. 4, 2017  According to the Centers for ... the end of October . PhysicianOne Urgent Care is helping communities across ... Westchester, NY , by offering no-cost* flu shots through the ... as mandated by certain health insurance regulations. ... The best time to get a flu shot is by the ...
Breaking Medicine Technology: