Navigation Links
Low levels of serum bilirubin spell higher lung cancer risk for male smokers
Date:4/7/2013

WASHINGTON, D.C. Elevated levels of bilirubin in the blood get attention in the clinic because they often indicate that something has gone wrong with the liver. Now researchers have found that male smokers with low levels of the yellow-tinged chemical are at higher risk for lung cancer and dying from the disease.

A team led by researchers at The University of Texas MD Anderson Cancer Center reported its findings in a late-breaking abstract at the AACR Annual Meeting 2013 in Washington, D.C.

"Our study indicates male smokers with low levels of bilirubin are a high-risk group that can be targeted with smoking cessation help, low-dose spiral CT screening of their lungs and other preventive measures," said senior author Xifeng Wu, M.D., Ph.D., professor and chair of MD Anderson's Department of Epidemiology and the Betty B. Marcus Chair in Cancer Prevention.

Lung cancer usually is diagnosed at a late stage, when tumors are inoperable and treatments largely ineffective. The overall five-year survival rate is 15 percent, but it falls to 5 percent for stage 3 lung cancer patients and 1 percent for those with stage 4 disease.

Spiral CT scans catch cancer early, biomarker could reduce false positives

The National Lung Screening Trial found that low-dose spiral computed tomography screening reduces mortality among heavy smokers by 20 percent. However, 95 percent of growths found by spiral CT are false positives, a barrier to large-scale screening.

"Validated biomarkers are urgently needed to improve risk prediction for lung cancer and to reduce false positives, shifting the balance toward more effective and efficient CT screening for cancer detection," Wu said.

The researchers started with an objective analysis of levels of metabolites substances produced during metabolism. Bilirubin is produced during the breakdown of old blood cells.

They analyzed 60 samples divided into three groups known as "trio
'/>"/>

Contact: Scott Merville
smerville@mdanderson.org
713-792-0661
University of Texas M. D. Anderson Cancer Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Despite Big Progress, Many Kids Have High Lead Levels in Blood
2. Vitamin D Levels in Pregnancy May Not Affect Kids Future Bone Health
3. Blood levels of fat cell hormone may predict severity of migraines
4. Metal-on-Metal Hip Implants: Bernstein Liebhard LLP Comments on New Study Finding Increased Metal Ion Levels May Predict Problems with Metal-on-Metal Hip Replacements
5. Cholesterol Levels May Vary By Season
6. Higher Indoor Humidity Levels Might Slow Flus Spread
7. Foods Might Serve Up High Levels of Chemicals Found in Plastics
8. Higher levels of several toxic metals found in children with autism
9. Doctors Health Press Reports on Study: Heart-Healthy Linoleic Acid Levels Decrease with Age
10. UCLA study finds endocrine disorder is most common cause of elevated calcium levels
11. Some cheeses exceed contaminant levels recommended by EU
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... Ireland (PRWEB) July 26, 2014 ... quality legal help to people who have suffered ... the launch of both their new company, and ... article on the new website explained, http://www.personalinjurysolicitorsireland.com/personal-injury-claims ... law. The focus of the company is always ...
(Date:7/25/2014)... CA (PRWEB) July 25, 2014 In recent ... about, and eager to reverse the symptoms associated with age-related ... the media at large, a new case study ... real benefits of testosterone therapy using bioidentical hormones. , ... 38-year-old father from Seattle who found himself beginning to feel ...
(Date:7/25/2014)... 2014 A federal judge has denied ... DePuy Pinnacle hip lawsuits ( http://www.depuypinnacle-lawsuit.com/ ) selected ... to go before a jury on September 1, 2014, ... July 18th, U.S. District Judge Ed Kinkeade of the ... claims may proceed to trial against Johnson & Johnson, ...
(Date:7/25/2014)... York, NY (PRWEB) July 25, 2014 ... ticket prices across the board for the Guinness International ... FC and Olympiacos FC at Soldier Field on ... also offering their customer appreciation promo/coupon/offer code SOCCER-2014 for ... an amazing year for diehard soccer fans in North ...
(Date:7/25/2014)... of America (GSA) the nation,s largest ... has chosen Heather M. Young, PhD, RN, ... the 2014 recipient of the Doris Schwartz Gerontological ... by GSA,s Health Sciences Section, is given to ... outstanding and sustained contribution to gerontological nursing research. ...
Breaking Medicine News(10 mins):Health News:PersonalInjurySolicitorsIreland.com Announces the Launch of their New Company and Website 2Health News:New Case Study Highlights Effectiveness of Testosterone Therapy in Fighting Weight Gain and Fatigue 2Health News:New Case Study Highlights Effectiveness of Testosterone Therapy in Fighting Weight Gain and Fatigue 3Health News:First Federal DePuy Pinnacle Hip Lawsuits Headed for Trial, As Judge Denies Defense Motions For Dismissal, Summary Judgment, Bernstein Liebhard LLP Reports 2Health News:First Federal DePuy Pinnacle Hip Lawsuits Headed for Trial, As Judge Denies Defense Motions For Dismissal, Summary Judgment, Bernstein Liebhard LLP Reports 3Health News:First Federal DePuy Pinnacle Hip Lawsuits Headed for Trial, As Judge Denies Defense Motions For Dismissal, Summary Judgment, Bernstein Liebhard LLP Reports 4Health News:Liverpool FC vs. Olympiacos FC Tickets Soldier Field: Ticket Down Slashes Ticket Prices for Guinness International Champions Cup in Chicago on Sunday, July 27th 2Health News:Young earns GSA's 2014 Doris Schwartz Gerontological Nursing Research Award 2
... HealthDay Reporter , WEDNESDAY, Oct. 5 (HealthDay ... early stage ,breast cancer using Herceptin and chemotherapy, while ... drug known as an anthracycline, improves survival while posing ... tested three different regimens, one of which did not ...
... CHAPEL HILL, N.C. -- Cam Patterson, MD, MBA, division ... at Chapel Hill School of Medicine has been named ... Association Judah Folkman Award in Vascular Biology. The ... at mid-career (within fifteen years of their first faculty ...
... HealthDay Reporter , WEDNESDAY, Oct. 5 (HealthDay ... can safely undergo MRIs to screen for cancer and ... a new study finds. Those procedures include only ... or later or defibrillators manufactured in 2000 or later, ...
... By Jenifer Goodwin HealthDay Reporter , WEDNESDAY, ... mice whose symptoms closely mimic autism in humans. ... the mice in this study come closer to mirroring ... in humans, said senior study author Matthew Anderson, an ...
... WEDNESDAY, Oct. 5 (HealthDay News) -- A new oral drug ... rates and disability progression, according to the results of a ... one of the few oral drugs that treat this type ... for many MS patients, researchers said. "Basically, these ...
... Amanda Gardner HealthDay Reporter , WEDNESDAY, Oct. 5 ... listeria first linked to tainted cantaloupes has risen to 18, ... 20 states, the U.S. Centers for Disease Control and Prevention ... the cantaloupes in question were recalled Sept. 14, more cases ...
Cached Medicine News:Health News:Drug Combo Might Fight Aggressive Breast Cancer More Safely 2Health News:Drug Combo Might Fight Aggressive Breast Cancer More Safely 3Health News:MRI Safe With More Recent Defibrillators, Pacemakers: Study 2Health News:MRI Safe With More Recent Defibrillators, Pacemakers: Study 3Health News:Scientists Engineer Mice That Have Autism 2Health News:Scientists Engineer Mice That Have Autism 3Health News:Experimental MS Drug Shows Promise 2Health News:Experimental MS Drug Shows Promise 3Health News:18 Deaths From Cantaloupe-Linked Listeria Outbreak: CDC 2Health News:18 Deaths From Cantaloupe-Linked Listeria Outbreak: CDC 3
(Date:7/24/2014)... and MARSEILLE, France , July 24, ... global license from University of Tokyo enables development of ... gene panels, for blood cancers  Mutations of ... favorable prognosis for patients with bone marrow disorders known ... developing companion diagnostics to guide treatment with new anti-cancer ...
(Date:7/24/2014)... 2014  IRIDEX Corporation (NASDAQ: IRIX ) ... 2014 financial results after the market closes on ... release, the Company will host a conference call with ... on Thursday, July 31, 2014 to ... developments. Interested parties may access the live ...
(Date:7/24/2014)... 24, 2014  IGI Laboratories, Inc. (NYSE MKT: IG), a ... announced its financial results for the second quarter ended June ... , Total revenues of $6.5 million in the second quarter ... in 2013 , Total revenues of $13.3 million for ... 78% over the same period in 2013 , Total ...
Breaking Medicine Technology:QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline 2QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline 3QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline 4QIAGEN Adds Promising Genomic Biomarkers for Assessing Prognosis in Treatment of Blood Cancers to Personalized Healthcare Pipeline 5IGI Laboratories Announces Second Quarter 2014 Results 2IGI Laboratories Announces Second Quarter 2014 Results 3IGI Laboratories Announces Second Quarter 2014 Results 4IGI Laboratories Announces Second Quarter 2014 Results 5IGI Laboratories Announces Second Quarter 2014 Results 6IGI Laboratories Announces Second Quarter 2014 Results 7
... Sept. 12, 2011 The National Association of ... that facilitates cooperation between law enforcement, healthcare professionals, ... prevention and investigation of drug diversion – today ... survey by the Substance Abuse and Mental Health ...
... HAYWARD, Calif., Sept. 12, 2011 Intarcia Therapeutics, ... abstracts on ITCA 650 (DUROS® subcutaneous continuous delivery ... diabetes at the 47th Annual Meeting of the ... Lisbon, Portugal.  All three presentations are scheduled for ...
Cached Medicine Technology:Intarcia Announces Presentations of Three Clinical Abstracts at the 47th Annual Meeting of the European Association for the Study of Diabetes 2Intarcia Announces Presentations of Three Clinical Abstracts at the 47th Annual Meeting of the European Association for the Study of Diabetes 3Intarcia Announces Presentations of Three Clinical Abstracts at the 47th Annual Meeting of the European Association for the Study of Diabetes 4
Inquire...
... work area that will help protect your ... irradiate the work area prior to use, ... be amplified. Containment features reduce the chance ... acrylic windows for a clear view, an ...
... x 24in(h). Designed to protect against ... The PCR Workstation irradiates the workspace prior ... airborne contamination by limiting exposure of experimental ... two fluorescent lights, one UV light, 12 ...
... Electropolished stainless steel ... mounts dampen vibration to ... as isolating vibration-producing equipment ... low-profile design allows for ...
Medicine Products: