Navigation Links
Low levels of natural antibodies behind stroke
Date:2/12/2010

The chances of suffering a stroke are linked to the presence of a certain type of antibody in the immune system, a new study from Karolinska Institutet shows. The researchers hope to be able to develop a vaccine that can mobilise the body's own defence against arteriosclerosis and stroke.

The research group, which was led by Professor Johan Frostegrd, has previously demonstrated that high levels of a certain type of antibody (anti-PC) in the immune defence are linked to a reduced risk of arteriosclerosis, a common cause of thrombosis and myocardial infarction.

In the present study, the researchers focused exclusively on stroke a blood clot in the brain and compared 227 individuals who had suffered stroke over a 13-year period with 445 sex and age-matched controls. After controlling for other risk factors (age, sex, smoking habits, cholesterol levels, diabetes, BMI and blood pressure), they were able to show that low levels (below 30 per cent of average) of PC antibodies correlated with a higher risk of stroke, which in women meant an almost three-fold increase.

The researchers have now advanced the hypothesis that low levels of natural PC antibodies, which can be a condition of a poor immune system contribute to the development of arteriosclerosis and its consequences, which include stroke.

"We're now examining the possibility of developing new immunological treatments for arteriosclerosis and stroke, either in the form of a vaccine to stimulate the immune defence or immunisation through the injection of antibodies," says Professor Frostegrd.


'/>"/>

Contact: Press Officer Katarina Sternudd
katarina.sternudd@ki.se
46-852-483-895
Karolinska Institutet
Source:Eurekalert

Page: 1

Related medicine news :

1. Dopamine Levels in Brain May Determine Social Status
2. Tests Show Top Tuna Brands Have High Mercury Levels
3. Protein Levels in Urine Help Predict Kidney Function
4. QuickMedial Praises New Study Linking High Cholesterol Levels to Increased Risk for Developing Alzheimer's Disease or Vascular Dementia
5. Low vitamin D levels associated with greater risk of relapse in childhood-onset multiple sclerosis
6. Low Vitamin D Levels are Associated With Greater Risk of Relapse in Childhood-Onset Multiple Sclerosis
7. Very Low Levels of Lead Harm Kids Kidneys: Study
8. Yoga reduces cytokine levels known to promote inflammation
9. Low Thyroid Levels May Up Need for Assisted Delivery
10. High Lipoprotein Levels Can Cause Heart Disease
11. Could Omega-3s Boost Blood Fat Levels?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2017)... ... May 24, 2017 , ... The CFOs included on ... health systems in the nation and help their organizations navigate the challenges in ... been instrumental in developing successful hospital and health system strategy. , Becker's Hospital ...
(Date:5/23/2017)... ... May 23, 2017 , ... Axiad IDS , a ... CIO Applications magazine has named the company a “Top 25 Cybersecurity Companies 2017.” ... Cloud to help organizations simply and proactively address potential cybersecurity threats before they happen. ...
(Date:5/23/2017)... , ... May 23, 2017 , ... ... technology and a 2017 Best in KLAS category winner, has named Daniel P. ... to extend and enhance its technology platform and product offerings,” says Justin Neece, ...
(Date:5/23/2017)... ... May 23, 2017 , ... ... patients on peri-implantitis in Las Vegas, NV, and the importance of ... gum disease consultation and leading care for peri-implantitis, with or without a referral. ...
(Date:5/23/2017)... ... ... New patients with symptoms of gum disease in San Diego, ... treatments from the doctors at Art of Dentistry, without first receiving a referral. Drs. ... of receiving qualified treatment in order to avoid systemic health effects associated with untreated ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)... CSSi, the global leader in patient recruitment, ... is proud to announce the launch of its newly ... both enriched content and a customized layout that provides ... already well-established position as the top global patient recruitment ... months of hard work, we are delighted to officially ...
(Date:5/9/2017)... WASHINGTON , May 9, 2017  Demonstrating ... the board of directors for the Pharmaceutical Research ... criteria for membership. Biopharmaceutical companies will now have ... in order to be eligible to join PhRMA. ... criteria, the board is sending a clear message ...
(Date:5/9/2017)... May 9, 2017  Semler Scientific, Inc. (OTCQB: ... solutions to improve the clinical effectiveness and efficiency ... the first quarter ended March 31, 2017. ... our customers to identify when preventive care options ... events like heart attacks or strokes occur," said ...
Breaking Medicine Technology: