Navigation Links
Low ghrelin - Reducing appetite at the cost of increased stress?
Date:9/13/2012

Philadelphia, PA, September 13, 2012 Ghrelin is a hormone released by the lining of the stomach that promotes feeding behavior. Decreasing ghrelin levels could potentially help combat obesity -- in fact, a vaccine that lowers ghrelin levels in order to reduce appetite is being studied as a treatment for obesity.

However, many people eat as a way to relieve stress. If low ghrelin levels increase stress, its effectiveness as a treatment for obesity may be reduced. In the current issue of Biological Psychiatry, researchers led by Dr. Zane Andrews of Monash University in Australia show that mice with no ghrelin are more anxious after stress, but that administration of endogenous ghrelin prevents the over-anxious response.

Previous studies have indicated that ghrelin can be either anxiety-causing or anxiety-relieving. This new set of studies now reveals that this dual role in anxiety behavior is context-dependent. Under non-stressed conditions, normal mice show mild anxiety relative to mice without ghrelin. Under acute stress, normal mice mount an appropriate ghrelin response to stress and are less anxious than no-ghrelin mice. In other words, stress-induced ghrelin release targets the body's stress system to stimulate a hormonal response that will combat the stress.

Ghrelin promotes the drive for food intake and maintains blood glucose during negative energy balance as well as subserving the rewarding nature of food. "We postulate that, under conditions of acute stress, ghrelin limits excessive anxious behavior by promoting the feeling of reward to ensure appropriate food-seeking behavior and maintain energy homeostasis. Consistent with this idea, studies from Jeff Zigman and colleagues showed that elevated ghrelin during calorie restriction produced anxiolytic responses in a test of anxious behavior," said Andrews.

"We hypothesize that ghrelin suppresses anxiety under acutely stressful conditions to encourage food seekin
'/>"/>

Contact: Rhiannon Bugno
Biol.Psych@utsouthwestern.edu
214-648-0880
Elsevier
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Reducing the side effects of treatment for prostate cancer
2. Timing of antibiotics important in reducing infections after C-section
3. Reducing Ozone Limits Would Save Lives, Report States
4. A nursing program shows promise for reducing deaths from chronic illnesses
5. HPV Vaccine Reducing Infections, Even Among Unvaccinated: Study
6. Kitchen exhaust fans vary in effectiveness in reducing indoor air pollution
7. No Progress in Reducing U.S. Motorcycle Deaths: Report
8. Reducing off-label use of antipsychotic medications may save money
9. Reducing post-traumatic stress after ICU
10. Researchers determine vitamin D blood level for reducing major medical risks in older adults
11. Experimental Drug Suppresses Appetite in Mice: Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/30/2014)... at least 2 years old to be covered by ... guidance exists other than the general recommendation by national ... least the first six months. , So what ... that motivated researchers at the University at Buffalo School ... patterns of American infants at 6 months and 12 ...
(Date:10/30/2014)... Timothy, InstaKNOT’s 4-year-old CEO, ... showing that you are never too young to give ... Tracey and Carl at the 2013 Santa Arriving By ... Beach Chamber of Commerce. Tracey gave Timothy a special ... wear his real fireman’s hat, and extending an offer ...
(Date:10/30/2014)... Five months after their expansion, the ... new branding and a website to accompany their recent ... Mepham’s promotion to name partner earlier this year, Hodgkinson ... Mepham’s name and better reflect their combined litigation expertise. ... decision to implement new branding reflects Hodgkinson Street Mepham’s ...
(Date:10/30/2014)... Reinberg HealthDay Reporter , WEDNESDAY, ... men with prostate cancer who also have certain heart problems ... a new study suggests. , , The therapy in question is ... to reduce levels of male hormones to prevent the growth ... current research, this hormone therapy was linked to triple the ...
(Date:10/30/2014)... Dr. Joseph Furlin MD, a certified obstetrician and gynecologist, has ... GYN in Melrose Park, IL and OB GYN ... about each of the care services and practice areas that ... and Spanish. The navigation of the website is easy ... Dr. Furlin’s patients with important information regarding his care methods ...
Breaking Medicine News(10 mins):Health News:What do American babies eat? A lot depends on Mom's socioeconomic background 2Health News:What do American babies eat? A lot depends on Mom's socioeconomic background 3Health News:4-year-old InstaKNOT CEO Honors Local Firefighters with Community Support 2Health News:4-year-old InstaKNOT CEO Honors Local Firefighters with Community Support 3Health News:4-year-old InstaKNOT CEO Honors Local Firefighters with Community Support 4Health News:Hodgkinson Street Mepham Rebrands 2Health News:Hormone Therapy May Up Heart-Related Deaths in Some Prostate Cancer Patients 2Health News:Hormone Therapy May Up Heart-Related Deaths in Some Prostate Cancer Patients 3Health News:Dr. Joseph Furlin Launches New Website with Information about Care Services 2
... Aug. 25 HealthWarehouse.com, Inc. (OTC Bulletin Board: HEWA) a ... for the second quarter ended June 30, 2009. The company ... in prescription sales and pharmacy transfers. Gross margins increased 7.8% ... $396,271. , , "Consumers are increasingly switching ...
... FT. WASHINGTON, Pa., Aug. 25 The makers of ZYRTEC(R) ... announced the availability of two new allergy solutions to help ... Children,s ZYRTEC(R) PERFECT MEASURE(R) and ZYRTEC(R) Itchy Eye Drops are ... products. The company also announced the launch of AllergyCast, ...
... , CHICAGO, Aug. 25 Health care costs are ... according to Aon Consulting, the global human capital consulting organization of ... (NYSE: AOC ). , , ... more than 60 leading health care insurers, representing more than 100 million ...
... food has been detected in unusually high levels in ... condition pre-eclampsia. These results are important because they ... pre-eclampsia and may help scientists to understand the cause ... at the University of Leeds took blood samples from ...
... polyps, sessile serrated polyps (also called sessile serrated adenomas), ... polyps share molecular features with a subgroup of colon ... be precursors of cancer through a hyperplastic polyp to ... arise in the proximal colon. Sessile serrated polyps may ...
... that connective tissue growth factor (CCN2) plays a ... systems. Fibrosis is a scarring condition that is ... cell function and can cause organ dysfunction and ... liver is the activation of hepatic stellate cells ...
Cached Medicine News:Health News:HealthWarehouse.com, Inc. Announces Second Quarter Financial Results; Revenues Increase Significantly Over Second Quarter 2008 2Health News:HealthWarehouse.com, Inc. Announces Second Quarter Financial Results; Revenues Increase Significantly Over Second Quarter 2008 3Health News:Just in Time for Allergy Season, ZYRTEC(R) Provides New Solutions for Adults and Children 2Health News:Just in Time for Allergy Season, ZYRTEC(R) Provides New Solutions for Adults and Children 3Health News:Just in Time for Allergy Season, ZYRTEC(R) Provides New Solutions for Adults and Children 4Health News:Employers Face 10.5 Percent Health Care Cost Increases, Says Aon Consulting 2Health News:Employers Face 10.5 Percent Health Care Cost Increases, Says Aon Consulting 3Health News:Employers Face 10.5 Percent Health Care Cost Increases, Says Aon Consulting 4Health News:Employers Face 10.5 Percent Health Care Cost Increases, Says Aon Consulting 5Health News:Employers Face 10.5 Percent Health Care Cost Increases, Says Aon Consulting 6Health News:New link between pre-eclampsia and diet 2Health News:Reinterpretation of proximal colon polyps called hyperplastic in 2001 2
(Date:10/30/2014)... , Oct. 30, 2014 Today Eli Lilly ... of its long-standing technology transfer program to increase the ... in 2003, the effort included Lilly donating manufacturing technology ... China , India ... South Africa – all MDR-TB ,hot spots., ...
(Date:10/27/2014)... 27, 2014 Research and Markets has ... 2014-2018" report to their offering. H1N1 ... a variant of the swine H1N1 virus, known as H1N1v ... nose, throat, and lungs. H1N1 virus is an RNA virus ... animal species such as humans, swine, birds, seals, and horses. ...
(Date:10/27/2014)... EAST TAUNTON, Mass. , Oct. 27, 2014 /PRNewswire/ ... the $15 billion global hip and knee replacement device market, ... and knee replacement technology at the American Association of ... the Sheraton Dallas Hotel in Dallas, Texas ... is a Bronze corporate partner of the organization. ...
Breaking Medicine Technology:Lilly Shares Insights from Decade-Long Technology Transfer Experience 2Lilly Shares Insights from Decade-Long Technology Transfer Experience 3Lilly Shares Insights from Decade-Long Technology Transfer Experience 4Global H1N1 Vaccines Market 2014-2018: Key Vendors are AstraZeneca, GlaxoSmithKline, Novartis and Sanofi Pasteur 2Global H1N1 Vaccines Market 2014-2018: Key Vendors are AstraZeneca, GlaxoSmithKline, Novartis and Sanofi Pasteur 3OMNIlife science to Exhibit at American Association of Hip and Knee Surgeons 24th Annual Meeting in Dallas November 6-9 2OMNIlife science to Exhibit at American Association of Hip and Knee Surgeons 24th Annual Meeting in Dallas November 6-9 3
... Bulletin Board: GOVX ) announced today the publication ... its HIV/AIDS vaccine products. The article, titled "Phase 1 Safety ... Vaccines Expressing HIV-1 Virus-like Particles," will appear in the March ... Diseases . A PDF of the article is available at ...
... Inc., a leader in room temperature biostability technology, ... (IQT). IQT is the independent, strategic investment firm ... mission of the U.S. Intelligence Community. ... pioneered recent innovations in ambient storage of biological ...
Cached Medicine Technology:GeoVax Announces Publication of Phase 1 Clinical Trial in The Journal of Infectious Diseases 2GeoVax Announces Publication of Phase 1 Clinical Trial in The Journal of Infectious Diseases 3GeoVax Announces Publication of Phase 1 Clinical Trial in The Journal of Infectious Diseases 4Biomatrica Secures Strategic Investment from IQT 2Biomatrica Secures Strategic Investment from IQT 3
Span Diagnostics Limited...
Malaria (P. fal.) Ag Rapid Test...
OptiMAL is a malaria test, for diagnosis and therapy control of an infection by Plasmodium species (Malaria)....
... The NOW® Malaria Test is a field or ... Malaria infection. It is intended for the detection ... and an antigen that is common to all ... (P.f.), Plasmodium vivax (P.v.), Plasmodium ...
Medicine Products: