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Low doses of arsenic cause cancer in male mice
Date:7/8/2014

ften occurs in excess in the drinking water of millions of people worldwide, and has been previously shown to be a human carcinogen.

In the study, more than half of the male offspring mice developed significant increases in benign and malignant lung tumors at the two lower doses (50 ppb and 500 ppb). Female offspring also developed benign tumors at the lower concentrations. Interestingly, the researchers did not find significant increases in lung tumors in either sex at the highest dose (5,000 ppb).

"Although this is only one study, it adds to a growing body of evidence showing adverse health effects from very low exposures to arsenic, raising the possibility that no level of arsenic appears to be safe," said Linda Birnbaum, Ph.D, director of the National Institute of Environmental Health Sciences (NIEHS) and NTP.


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Contact: Robin Mackar
rmackar@niehs.nih.gov
919-541-0073
NIH/National Institute of Environmental Health Sciences
Source:Eurekalert  

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