Navigation Links
Low-dose aspirin does not appear to reduce risk of CV events in patients with diabetes
Date:11/9/2008

and suggest the need to conduct additional studies of aspirin for primary prevention of cardiovascular disease in diabetic patients."

(JAMA. 2008;300 [18]: 2134-2141. Available pre-embargo to the media at www.jamamedia.org.)

Editor's Note: This study was supported by the Ministry of Health, Labour and Welfare of Japan. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Editorial: Aspirin For Primary Prevention Still an Open Question for Patients with Diabetes

"The use of aspirin for primary prevention of cardiovascular events in individuals with diabetes is widely recommended by existing guidelines, but the evidence supporting its efficacy is surprisingly scarce," writes Antonio Nicolucci, M.D., from Consorzio Mario Negri Sud, Italy, in an accompanying editorial.

"The lack of precision and the low statistical power in the JPAD trial are the consequence of the substantially lower than expected event rate in the trial population." Dr. Nicolucci writes that the study population had a very low baseline risk of cardiovascular events and questions whether the results can be generalized to other populations with substantially higher cardiovascular risks.

"The issue of aspirin therapy for patients with diabetes is an example of how, in the presence of a long-lasting uncertainty, scientific organizations or governmental bodies should provide the foundation for answering this question by promoting pragmatic, large-scale clinical trials. Considering all diabetic patients with no history of cardiovascular disease (except those with documented contraindications or perceived indications) as candidates for randomized clinical trials would represent a major contribution to the credibility of scientific methods in guiding practice."

(JA
'/>"/>

Contact: Hisao Ogawa, M.D., Ph.D.
ogawah@kumamoto-u.ac.jp
JAMA and Archives Journals
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. AUDIO from Medialink and Bayer: Lifesaving Benefits of Low-Dose Aspirin Therapy Maintained with Naproxen Sodium
2. Bayer Marketing Two Unapproved Aspirin Products: FDA
3. New CHARISMA Outcome Study Results Validate Aspirin Effect
4. Breakthrough Testing for Patients on Aspirin Therapy for Preventing Heart Attacks
5. Statement From Bayer(R) Aspirin Regarding the American Medical Associations New Aspirin Policy Resolution
6. Aspirin at Bedtime Lowers Blood Pressure
7. Anti-Clotting Drug as Good as Aspirin at Stopping Second Stroke
8. Daily Aspirin May Reduce Breast Cancer Risk
9. Daily aspirin may reduce risk of common type of breast cancer
10. Aspirin-like compounds increase insulin secretion in otherwise healthy obese people
11. Will botox be the aspirin of the 21st century?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/14/2014)... 2014 According to the Boost Your Bust book ... women who want to learn how to increase the size of ... of 7 chapters including:, , Chapter 1 – ... Chapter 2 – How Natural Breast Enlargement Works , ... Bigger , Chapter 4 – The Groundwork , ...
(Date:7/14/2014)... Vaginal Mesh lawsuit claims continue to mount ... manufacturers in the U.S. District Court, Southern District of ... complaints are pending against pelvic mesh manufacturers that include ... No. 2325), and C.R. Bard, Inc., (MDL No. 2187). ... lawsuit claims pending, according to statistics from the U.S. ...
(Date:7/14/2014)... that promote mental activity, and moderate physical activity ... development of Alzheimer,s disease and dementia in later ... the Alzheimer,s Association International Conference 2014 (AAIC 2014) ... 2014 also showed that sleep problems especially ... may increase dementia risk in veterans. Additionally, in ...
(Date:7/14/2014)... (PRWEB) July 14, 2014 Love Digits ... iTunes, called Love Digits. The App brings ancient astrology ... alike to quantify their compatibility using a five-star rating ... two people can instantaneously test their compatibility for love ... measures. , The app’s five-star rating system generates a ...
(Date:7/14/2014)... Summer is the best season of the ... beach, swimming and other outdoor adventures. The promotional product experts ... and healthy all summer long. The promo product gurus at ... must-have custom imprinted products everyone must have on hand this ... sunblock. Sunscreen helps protect skin from harmful UV ...
Breaking Medicine News(10 mins):Health News:Boost Your Bust Book Review Exposes Jenny Bolton's Breast Enhancement Guide – Vkool.com 2Health News:Boost Your Bust Book Review Exposes Jenny Bolton's Breast Enhancement Guide – Vkool.com 3Health News:Nearly 60,000 Vaginal Mesh Lawsuit Claims Filed Against Seven Different Pelvic Mesh Manufacturers 2Health News:Nearly 60,000 Vaginal Mesh Lawsuit Claims Filed Against Seven Different Pelvic Mesh Manufacturers 3Health News:Nearly 60,000 Vaginal Mesh Lawsuit Claims Filed Against Seven Different Pelvic Mesh Manufacturers 4Health News:Nearly 60,000 Vaginal Mesh Lawsuit Claims Filed Against Seven Different Pelvic Mesh Manufacturers 5Health News:Potential Alzheimer's disease risk factor and risk reduction strategies become clearer 2Health News:Potential Alzheimer's disease risk factor and risk reduction strategies become clearer 3Health News:Potential Alzheimer's disease risk factor and risk reduction strategies become clearer 4Health News:Potential Alzheimer's disease risk factor and risk reduction strategies become clearer 5Health News:Potential Alzheimer's disease risk factor and risk reduction strategies become clearer 6Health News:Love Digits, Numerical Approach to Modern Love, Now Available on iTunes 2Health News:Love Digits, Numerical Approach to Modern Love, Now Available on iTunes 3Health News:Why These Three Summer Essentials from 4AllPromos Can Improve Summer 2
... BROOK, Ill. Radiologists who interpret a high volume of ... determining which suspicious lesions are not malignant, according to a ... of Radiology . "Contrary to our expectations, we ... study,s lead author, Diana S.M. Buist, Ph.D., M.P.H., senior investigator ...
... errors isn,t quite as new as it seems. A Johns ... the turn of the last century, has turned up copious ... suggestions for preventing those mistakes in the future. Authors ... Surgery , suggest that such open documentation may have played ...
... MONDAY, Feb. 21 (HealthDay News) -- Implementing practical, environmentally ... could reduce health-care costs without compromising patient safety, says ... facilities are a major source of waste products, producing ... 4 billion pounds a year. Nearly 70 percent of ...
... By Serena Gordon HealthDay Reporter , MONDAY, Feb. ... in northern climates aren,t imaging that their misery is lasting ... for people living in some northern U.S. states, the length ... weeks, and for people living in some areas of Canada, ...
... , MONDAY, Feb. 21 (HealthDay News) -- Seniors who ... researchers say. The study from Rush University in Chicago ... no type of disability at the start of the study ... provided information about their social activities, such as going out ...
... million grant from the National Institutes of Health (NIH) ... biomarkers that may be linked to the development and ... in children. Nationwide Children,s is home to the only ... with an NIH-sponsored clinical study. A hemangioma is ...
Cached Medicine News:Health News:Higher volume reduces false positives in screening mammography 2Health News:Famed neurosurgeon's century-old notes reveal 'modern' style admission of medical error 2Health News:Going 'Green' May Cut Hospital Costs 2Health News:Climate Change Extending Ragweed Season in Colder Climes: Study 2Health News:Climate Change Extending Ragweed Season in Colder Climes: Study 3Health News:Busy Social Life May Stave Off Disability in Elderly 2Health News:$1.9 million NIH grant supports research in the most common soft tissue tumor in children 2
(Date:7/11/2014)... , July 11, 2014 Neurelis, Inc. ... ("Biotie") to end the option held by Biotie to ... further development of NRL-1 (intranasal diazepam) for pediatric and ... Over the past year, Biotie has advanced the ... preparation for the pivotal clinical work required for NDA ...
(Date:7/10/2014)... NEWS, Virginia , 11. Juli ... Hersteller von Kameras für die molekulare ... (MBI/BSGI), hat heute die CE-Zulassung für ... dem CE-Zeichen kann Dilon das Produkt ... Vertriebsbereich auf den Großteil der europäischen ...
(Date:7/10/2014)... 2014  Breg, Inc., a premier provider of ... FreeRunner™ knee brace with new innovations to help ... return to active lifestyles.  FreeRunner,s patent-pending design acts ... support when patients need it most, and the ... Patellofemoral issues are the most common cause ...
Breaking Medicine Technology:Neurelis Regains Rights to Intranasal Diazepam Program 2Neurelis Regains Rights to Intranasal Diazepam Program 3Dilon erhält CE-Zulassung für sein Navigator-Gamma-Sondensystem 2Breg Introduces Knee Brace to Help Runners with Patellofemoral Pain Syndrome 2
... privately-held therapeutic device company, today announced that DEKRA and Health ... Matrix for clinical use and sale in Europe and Canada. ... resistant, and absorbable putty designed to rapidly stop bleeding when ... cut bone is a problem in many operative procedures including ...
... announces that a new market research report is available ... Deals Analysis 2011 http://www.reportlinker.com/p0180789/Medical-Equipment-Annual-Deals-Analysis-2011.html ... Summary GlobalData,s "Medical Equipment ... of data and trend analysis on mergers and acquisitions ...
Cached Medicine Technology:ORTHOCON® Receives CE Mark and Health Canada Medical Device License for HEMASORB® 2Reportlinker Adds Medical Equipment Annual Deals Analysis 2011 2Reportlinker Adds Medical Equipment Annual Deals Analysis 2011 3Reportlinker Adds Medical Equipment Annual Deals Analysis 2011 4Reportlinker Adds Medical Equipment Annual Deals Analysis 2011 5Reportlinker Adds Medical Equipment Annual Deals Analysis 2011 6Reportlinker Adds Medical Equipment Annual Deals Analysis 2011 7Reportlinker Adds Medical Equipment Annual Deals Analysis 2011 8Reportlinker Adds Medical Equipment Annual Deals Analysis 2011 9Reportlinker Adds Medical Equipment Annual Deals Analysis 2011 10Reportlinker Adds Medical Equipment Annual Deals Analysis 2011 11Reportlinker Adds Medical Equipment Annual Deals Analysis 2011 12Reportlinker Adds Medical Equipment Annual Deals Analysis 2011 13Reportlinker Adds Medical Equipment Annual Deals Analysis 2011 14Reportlinker Adds Medical Equipment Annual Deals Analysis 2011 15Reportlinker Adds Medical Equipment Annual Deals Analysis 2011 16
... complete line of enteric disease ... and monoclonal/polyclonal antibody-based ELISA tests ... pathogens in fecal specimens. Our ... difficile, Entamoeba histolytica, Giardia, Cryptosporidium ...
... II test is also available with Inverness ... greatly reduces the hands-on time required to ... testing. The Fecal-Quik-Prep device is a unique ... amount of hands-on time required to prepare ...
... for autoimmune testing feature single-well ANA screen ... specific reflex tests including dsDNA, and 6 ... SS-B (La), Scl-70 and Jo-1. In addition, ... line of products for Cardiolipins (IgA, IgG, ...
... Our ELISA products for autoimmune testing ... ELISAs, as well as specific reflex tests ... Sm, Sm/RNP, SS-A (Ro), SS-B (La), Scl-70 ... family includes a full line of products ...
Medicine Products: