Navigation Links
Low and high vitamin D levels in older women associated with increased likelihood of frailty
Date:12/8/2010

Chevy Chase, MDA recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM) found that lower and higher vitamin D levels were associated with an increased likelihood of frailty in older women. Women with vitamin D levels between 20.0 and 29.9 ng/ml were at the lowest risk of frailty.

Vitamin D deficiency and frailty are common with aging. Dimensions of frailty, including weakness and slowness are potential outcomes of vitamin D deficiency and many experts have recommended measuring vitamin D levels in older adults and prescribing vitamin D supplementation if levels are less than 30 ng/ml to prevent adverse health outcomes. This new study however found a U-shaped relationship between vitamin D levels and frailty; older women with vitamin D levels higher than 30 ng/ml and those with levels lower than 20 ng/ml were more likely to be frail.

"Vitamin D supplementation has grown in popularity, yet the association between vitamin D status and risk of adverse health outcomes in older adults is uncertain," said Kristine Ensrud, MD, professor of medicine and epidemiology, Minneapolis VA Medical Center and the University of Minnesota and lead author of the study. "Our study did not find that higher vitamin D status was associated with lower subsequent risks of frailty or death. In fact, higher levels of vitamin D were associated with increased likelihood of frailty."

In this study, researchers measured vitamin D levels and assessed frailty status in a cohort of 6,307 women aged 69 and older. To determine whether lower vitamin D levels were associated with an increased risk of greater frailty status at a later date, 4,551 women classified as non-frail at baseline had frailty status reassessed an average of 4.5 years later. They found that older women with vitamin D levels less than 20 ng/ml and more than 30 ng/ml had higher odds of frailty at baseline. Lower vitamin D levels among non-frail women at baseline were associated with an increased risk of frailty or death at follow-up.

"Evidence is lacking to support use of vitamin D supplementation for prevention of frailty and other outcomes including cancer or all-cause mortality," said Ensrud. "Our results indicate that well-designed large randomized trials of sufficient duration are needed to accurately quantify health effects of vitamin D supplementation, including whether or not supplementation reduces the incidence or progression of frailty in older adults."


'/>"/>

Contact: Aaron Lohr
alohr@endo-society.org
240-482-1380
The Endocrine Society
Source:Eurekalert

Related medicine news :

1. IOF statement on new IOM dietary reference intakes for calcium and vitamin D
2. Vitamin D Guidelines Edge Upwards, But Most Americans Getting Enough: Report
3. CRN reacts to Institute of Medicine DRI recommendations for vitamin D
4. Vitamin D and calcium -- updated dietary reference intakes from IOM
5. Genes Influence Vitamin D Levels, But Only in Winter: Study
6. New drug targets vitamin D receptors in hormone resistant prostate cancers
7. Vitamin D Shortage Not Tied to Stroke Deaths in Blacks: Study
8. Low Vitamin D Linked to Deterioration in Certain Leukemia Patients
9. Study Finds Vitamins E and C Dont Reduce Cataract Risk in Men
10. Vitamin D No Magic Bullet for Osteoarthritis
11. Vitamin E May Pose Slight Bleeding-Stroke Risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/17/2017)... , ... January 17, 2017 , ... Gym Source, America’s ... a new showroom at South Dixie Hwy in Miami, FL. , “We are elated ... Source. “The new innovative in-store concept is designed to give clients a seamless and ...
(Date:1/17/2017)... ... January 17, 2017 , ... ... events, Dr. Carol Francis re-releases powerfully uplifting interview with medical expert and prolific ... everyone endure and pass through tough times, Dr. Bernie Siegel energizes listeners to ...
(Date:1/17/2017)... Florida (PRWEB) , ... January 17, 2017 , ... Kevin ... Producers of AsSeenOnTV.pro will be featuring DRTV campaigns regarding the topic of Beauty and ... become a better version of themselves. What better way to commit to these changes ...
(Date:1/17/2017)... ... January 17, 2017 , ... ... Palm Desert, is opening a new office in San Clemente, California this month. ... (dTMS) in Southern California, successfully treating individuals struggling with major depression. Depression impacts ...
(Date:1/17/2017)... ... January 17, 2017 , ... ... joined the Peoples Health network on Dec. 1, 2016. Peoples Health, a Metairie-based ... Medical Center is an exciting addition to our provider network, and the addition ...
Breaking Medicine News(10 mins):
(Date:1/18/2017)... 2017   Spotlight Innovation Inc. (OTCQB: ... in the second quarter of 2017, to launch ... to provide relief from chronic pain, is a ... was developed under a licensing agreement with Dr. ... from snake venom. Additionally, Caretta Therapeutics has signed ...
(Date:1/18/2017)... , Jan 18, 2017 Research and Markets ... Vomiting Drugs Market 2017-2021" report to their offering. ... The global CINV drugs ... 2017-2021. Global Thoracic Surgery Market 2017-2021, has been ... experts. The report covers the market landscape and its growth prospects ...
(Date:1/18/2017)... -- In China , we say Health ... of China,s Healthy Strategy originates. 2016 ... Economic and Social Development of the People,s Republic ... state council of the People,s Republic of China ... development plan, identifying medical devices as one of the main ...
Breaking Medicine Technology: