Navigation Links
Low Vitamin D Linked to Deterioration in Certain Leukemia Patients
Date:11/12/2010

FRIDAY, Nov. 12 (HealthDay News) -- Patients with a certain type of leukemia who had insufficient vitamin D levels when their cancer was diagnosed saw their disease progress much faster and were two times more likely to die than those with adequate vitamin D levels, a new study finds.

Researchers also discovered that increasing vitamin D levels in patients was linked to longer survival times, even after controlling for other factors associated with leukemia progression.

This is an important finding for both patients and doctors, according to the researchers at the Mayo Clinic in Rochester, Minn. and the University of Iowa.

The disease -- chronic lymphocytic leukemia (CLL) -- is cancer of the white blood cells (lymphocytes) and mainly affects adults. Although CLL is often diagnosed at an early stage, the standard approach is to wait until patients develop symptoms before beginning chemotherapy, explained study author and hematologist Dr. Tait Shanafelt.

"This watch-and-wait approach is difficult for patients because they feel there is nothing they can do to help themselves," Shanafelt said in a Mayo news release. "It appears vitamin D levels may be a modifiable risk factor for leukemia progression. It is simple for patients to have their vitamin D levels checked by their physicians with a blood test. And if they are deficient, vitamin D supplements are widely available and have minimal side effects."

This study of 390 CLL patients found that 30 percent of them had insufficient vitamin D levels (less than 25 nanograms per milliliter) at the time of cancer diagnosis. After a median follow-up of three years, patients with insufficient vitamin D levels were 66 percent more likely to have disease progression and to require chemotherapy. They also had a twofold increased risk of death, compared to those with adequate vitamin D levels.

Similar findings were seen in a different group of CLL patients who were followed for 10 years, according to the researchers.

"This tells us that vitamin D insufficiency may be the first potentially modifiable risk factor associated with prognosis in newly diagnosed CLL," Shanafelt said.

The researchers are planning another study to see if reversing low vitamin D levels in patients will improve their prognosis.

The study appears online in the journal Blood.

More information

The Leukemia and Lymphoma Society has more about chronic lymphocytic leukemia.

-- Robert Preidt

SOURCE: Mayo Clinic, news release, Nov. 4, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Study Finds Vitamins E and C Dont Reduce Cataract Risk in Men
2. Vitamin D No Magic Bullet for Osteoarthritis
3. Vitamin E May Pose Slight Bleeding-Stroke Risk
4. Insufficient vitamin D levels in CLL patients linked to cancer progression and death
5. Genetics May Play Role in Vitamin E Levels
6. New clinical trial explores role of vitamin D in preventing esophageal cancer
7. Vigilance Against Skin Cancer May Lead to Lack of Vitamin D
8. Vitamin D deficiency linked to lung transplant rejection
9. Can Vitamin B12 Reduce Alzheimers Risk?
10. Vitamin D-ficiency common among orthopaedic surgery
11. Using cassava to address vitamin A deficiency
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Low Vitamin D Linked to Deterioration in Certain Leukemia Patients
(Date:6/25/2016)... , ... June 25, 2016 , ... First Choice ... States, named Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm ... Medical Director of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical ...
(Date:6/25/2016)... ... , ... Conventional wisdom preaches the benefits of moderation, whether it’s a matter ... bar too high can result in disappointment, perhaps even self-loathing. However, those who set ... , Research from PsychTests.com reveals that behind the tendency to set low ...
(Date:6/24/2016)... ... ... crisis. Her son James, eight, was out of control. Prone to extreme mood shifts and ... him, he couldn’t control his emotions,” remembers Marcy. “If there was a knife on ... say he was going to kill them. If we were driving on the freeway, ...
(Date:6/24/2016)... ... 2016 , ... Comfort Keepers® of San Diego, CA is excited to announce ... program to drive cancer patients to and from their cancer treatments. Comfort Keepers ... of life and ongoing independence. Getting to and from medical treatments is one ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... Living, is proud to recognize Dr. Barry M. Weintraub as a prominent plastic ... most beautiful women in the world, and the most handsome men, look naturally ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 2016 The Academy of Managed Care Pharmacy ... that would allow biopharmaceutical companies to more easily share ... formulary and coverage decisions, a move that addresses the ... The recommendations address restrictions in the sharing ... drug label, a prohibition that hinders decision makers from ...
(Date:6/24/2016)... 24, 2016   Pulmatrix, Inc ., (NASDAQ: ... inhaled drugs, announced today that it was added to ... its comprehensive set of U.S. and global equity ... an important milestone for Pulmatrix," said Chief Executive Officer ... of our progress in developing drugs for crucial unmet ...
(Date:6/23/2016)... Any dentist who has made an implant supported ... Many of them do not even offer this as a ... laboratory costs involved. And those who ARE able to offer ... high cost that the majority of today,s patients would not ... Zadeh , founder of Dental Evolutions Inc. and inventor of ...
Breaking Medicine Technology: