Navigation Links
Low Vitamin D Could Raise Death Risk
Date:6/23/2008

Study is among the first to show such an effect from a nutrient, experts say

MONDAY, June 23 (HealthDay News) -- People with heart disease and low levels of vitamin D may be at increased risk of dying from all causes and particularly from cardiovascular disease, a new study suggests.

Some 50 percent to 60 percent of older people in North America and the rest of the world have insufficient levels of vitamin D. The same is true for younger people. Low levels of vitamin D -- which can be sourced from sunlight exposure or supplements -- have been associated with falls, fractures, cancer, immune dysfunction, cardiovascular disease, and high blood pressure, researchers report. Now, a new study links insufficient vitamin D with the risk of dying.

"This is a very important study that shows low vitamin D, and low vitamin D hormone levels, are associated with cardiovascular mortality and mortality itself in a population of patients with coronary heart disease," said Robert U. Simpson, a professor in the department of pharmacology at the University of Michigan School of Medicine. He was not involved in the study.

"This study supports the current interest in raising the minimum daily requirement for vitamin D and encouraging greater surveillance of vitamin D status in the general population and specifically heart disease patients," Simpson said.

The report was published in the June 23 edition of the Archives of Internal Medicine.

In the study, Dr. Harald Dobnig, from the Medical University of Graz in Austria, and colleagues collected data on vitamin D levels among almost 3,300 patients undergoing angiography.

After more than seven years of follow-up, 737 patients had died, 463 of them from cardiovascular disease.

Dobnig's team found that death rates from any cause, and from cardiovascular disease, were higher among people with the lowest levels of vitamin D.

"Apart from the proved effects that vitamin D has on bone metabolism and neuromuscular function, appropriate serum levels are associated with a decrease in mortality," the researchers wrote.

"Although not proved, it seems possible that at least part of this effect may be due to lowering of a risk profile promoting atherosclerosis and preventing cardiovascular end points," they concluded.

Dr. Gregg C. Fonarow, a professor of cardiology at the University of California, Los Angeles, noted that similar observations with low vitamin E and beta carotene levels and cardiovascular mortality were not confirmed when vitamin supplementation was tested in clinical trials.

"Prospective randomized clinical trials of vitamin D supplementation demonstrating a reduction in cardiovascular mortality are absolutely needed before any treatment recommendations can be made," Fonarow said. "The few clinical trials of vitamin D supplementation conducted to date have been quite disappointing."

Vitamin D also appears to play a role in preventing heart failure, another study finds.

In a study, published online in Journal of Cardiovascular Pharmacology, University of Michigan pharmacologist Simpson showed that vitamin D could prevent heart failure from developing in rats.

After 13 weeks, Simpson's team found that rats prone to heart failure that received vitamin D supplements had significantly lower signs of heart failure compared with similar rats not given the nutrient.

The hearts of the treated rats weighed less and worked less well during each beat. However, blood pressure was maintained indicating that there was no reduction in heart function, according to the report.

More information

For on vitamin D, visit MedlinePlus.



SOURCES: Robert U. Simpson, Ph.D., professor, department of pharmacology, University of Michigan School of Medicine, Ann Arbor; Gregg C. Fonarow, M.D., professor, cardiology, University of California, Los Angeles; June 23, 2008, Archives of Internal Medicine; online issue, Journal of Cardiovascular Pharmacology


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Study shines more light on benefit of vitamin D in fighting cancer
2. Vitamin Es lack of heart benefit linked to dosage
3. Fat transforms vitamin C from good cop into bad cop
4. Vitamin C Plus Fat Might Spur Cancer
5. How vitamin C stops the big C
6. Vitamin D Supplements May Lengthen Life
7. Joint Juice Launches New Ready-to-Drink Glucosamine & Vitamin-Enhanced Dietary Supplement Water Nationwide
8. Vitamin Relief Brings Needed Nutrition to School District Resurrecting After Katrina
9. Excessive Multivitamin Use May Raise Risk for Prostate Cancer, from Harvard Mens Health Watch
10. As Winter Approaches, Risk for Vitamin D Deficiency Increases
11. Vitamin D Wont Help Prevent Most Cancers
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Low Vitamin D Could Raise Death Risk
(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder of ... ElderCounsel, a national organization of elder law and special needs planning attorneys. “Membership in ... It also provides a forum to network with elder law attorneys nationwide,” said Somekh. ...
(Date:10/13/2017)... LUIS OBISPO, Calif. (PRWEB) , ... October 13, 2017 , ... ... Alzheimer’s or dementia. However, many long-term care insurance companies have a waiver for care ... is the 90-day elimination period, when the family pays for care, is often waived, ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network ... advocate for action towards gender equality at their inaugural Summit in New York City ... and reached a social audience of over 3 million. To watch the Mobilize Women ...
(Date:10/13/2017)... ... 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh, ... and least understood books in the Holy Scriptures, Revelation. The Book of Revelation paints ... for centuries. Many have tossed it off as mere rubbish, but Yisrayl Hawkins says ...
(Date:10/13/2017)... ... October 13, 2017 , ... Coveros, a leader in ... awarded a contract by the Center for Medicare and Medicaid Services (CMS). The ... enterprise use of Agile methodologies in a consistent and high value manner across ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... , Oct. 11, 2017  Hill-Rom Holdings, Inc. ... Aspen Surgical facility in Las Piedras, Puerto ... scalpels and blades. ... that the facility sustained minor structural damage, temporary loss ... Maria. Repairs have been completed, manufacturing operations have resumed, ...
(Date:10/7/2017)... , Oct. 6, 2017   Provista, a ... than $100 billion in purchasing power, today announced a ... information. The Newsroom is the online home ... trends, infographics, expert bios, news releases, slideshows and events. ... to a wealth of resources at their fingertips, viewers ...
(Date:10/4/2017)... 2017  According to the Centers for Disease Control and Prevention (CDC), ... PhysicianOne Urgent Care is helping communities across Massachusetts , ... by offering no-cost* flu shots through the end of the month. ... insurance regulations. ... get a flu shot is by the end of October, according to ...
Breaking Medicine Technology: