Navigation Links
Low Doses of Red Wine Chemical May Fight Diabetes
Date:10/2/2007

Resveratrol has already been shown to offer heart benefits

TUESDAY, Oct. 2 (HealthDay News) -- Chinese researchers have outlined the molecular chain of activity that makes resveratrol, a chemical found in the skin of red grapes and in red wine, a promising candidate for treatment of diabetes and other conditions.

The study focused on how resveratrol improved the sensitivity of mice to insulin, an effect that could lead to new treatments for type 2 diabetes, in which human cells lose their sensitivity to insulin.

And U.S. experts said the chemical's effect on a number of different tissues could eventually lead to such dreamed-of medications as an effective diet pill.

The study, by researchers at the Chinese Academy of Sciences in Shanghai, showed that resveratrol activates an enzyme called SIRT1. This enzyme, in turn, suppresses the activity of a molecule called PTP1B, which ordinarily works to decrease insulin activity. SIRT1 levels were reduced in the animals' insulin-resistant cells. Increasing SIRT1 activity with resveratrol improved insulin sensitivity by acting on PTP1B.

The study is published in the October issue of Cell Metabolism.

"When you suppress PTP1B, insulin activity improves," said Young-Bum Kim, an assistant professor of medicine at Beth Israel Deaconess Medical Center in Boston, one author of an accompanying editorial in the journal.

"SIRT1 has a variety of functions in the body," Kim said. "Now we can move on to other tissues, such as the brain. It is possible that regulating the hypothalamus with SIRT1 can prevent diet-induced obesity."

That is clearly a long-term goal, said Janice M. Zabolotny, an instructor in medicine at Beth Israel Deaconess, and the other author of the editorial.

"But it can make animals want less food and lower body weight," she said. "By activating SIRT1, you could block the expression of PTP1B and get the same hopef
'/>"/>

Copyright©2007 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Low doses of chemotherapy good for children
2. Lower doses of oral contraceptives helpful in treating acne
3. India To Procure 1 Million Doses Of Tamiflu
4. Small Doses Of Radiation Can Help Certain Lung Cancer Patients
5. Polyphenols in Green Tea Cause Liver Damage At High Doses
6. Pre-eclampsia Pronounced With Intake of Vitamins in Large Doses
7. Stronger Doses Fewer Administration for Breast Cancer
8. High Doses Of Common Pain killers Can Double The Chances Of Heart attack
9. Two doses of chickenpox vaccine more effective
10. Even Normal Doses Of Tylenol Could Damage Liver
11. Allergic Individuals Should Carry Two Doses Of EpiPen Says Quebec Coroner
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2014)... of flatulence and have a reputation for being highly toxic, ... is now being being found to offer potential health benefits ... attacks and dementia. A new compound (AP39), designed and made ... future therapies, by targeting delivery of very small amounts of ... , Scientists in Exeter have already found that the ...
(Date:7/9/2014)... A retrospective study conducted by researchers at Tufts University ... adults with intellectual and developmental disabilities, the likelihood of ... dental care increased. The findings, published in the July/August ... help improve interventions designed to address the oral health ... reviewed the dental records of 107 patients at one ...
(Date:7/9/2014)... , , , , ... , , , AUDIO: , ... approximately 30cm from the bullet... , , Click here for ... , , , , , ... , , , , , University of Southampton researchers, with assistance from the Ministry of ...
(Date:7/9/2014)... School of Medicine of the University of Southern ... specific component of the immune system are completely ... infection. The discovery suggests that blocking this immune ... autoimmune and hyper-inflammatory diseases such as rheumatoid arthritis ... published online on June 23 in The ...
(Date:7/8/2014)... The Department of Defense,s Defense Advanced Research Projects ... up to $2.5 million to develop an implantable ... stimulate neurons within the brain to help restore ... research builds on the understanding that memory is ... of the brain encode information, store it and ...
Breaking Medicine News(10 mins):Health News:Rotten egg gas holds key to healthcare therapies 2Health News:Adults with special needs see gains, challenges with long term oral care 2Health News:Adults with special needs see gains, challenges with long term oral care 3Health News:Fit for the frontline? New study identifies the hearing requirements of British soldiers 2Health News:Fit for the frontline? New study identifies the hearing requirements of British soldiers 3Health News:Fit for the frontline? New study identifies the hearing requirements of British soldiers 4Health News:Fit for the frontline? New study identifies the hearing requirements of British soldiers 5Health News:Fit for the frontline? New study identifies the hearing requirements of British soldiers 6Health News:Fit for the frontline? New study identifies the hearing requirements of British soldiers 7Health News:DARPA selects Lawrence Livermore to develop world's first neural device to restore memory 2Health News:DARPA selects Lawrence Livermore to develop world's first neural device to restore memory 3
... When patients choose to leave the hospital before the ... of inadequately treated medical conditions and the need for ... issue of Mayo Clinic Proceedings . Additionally, the ... predictors and potential interventions to help manage and improve ...
... in the international journal Chest , by Neil ... disease (COPD) who breathed a mix of 60% helium ... to exercise longer and harder than those who breathed ... significant because research has shown that patients who perform ...
... 2009Chemicals present in cranberriesand not the acidity of cranberry ... the cells that line the urinary tract, as documented ... Food , a peer-reviewed journal published by Mary Ann ... free online at www.liebertpub.com/jmf , Urinary tract ...
... Provide Information on Medicare Advantage Special Needs Plans, ... March 9 A series of free seminars ... illness maintain a healthy lifestyle and learn about ... unique needs will be offered during March at ...
... continued growthATLANTA, March 9 Reveille Software(TM) ... grown to 275 customers and expanded its ... itself for continued market growth in helping ... performance management.Reveille,s solution, Reveille Experience and Performance ...
... study show continued, significant relief of depressive symptoms, ... hospitalization and death among ESRD patientsLAWRENCE, Mass., March ... NXTM ), a leading manufacturer of innovative dialysis ... its ongoing FREEDOM study, which show that the ...
Cached Medicine News:Health News:Patients being discharged against medical advice 2Health News:Helium helps lung patients breathe easier 2Health News:New research reveals how cranberry products prevent urinary tract infections 2Health News:Seminars Offered to Missouri Seniors With Diabetes and Other Chronic Illnesses 2Health News:Reveille Software Reaches Customer Milestone and Expands Executive Team 2Health News:Reveille Software Reaches Customer Milestone and Expands Executive Team 3Health News:NxStage Reports Sustained Reduction in Clinical Depressive Symptoms for Daily Home Hemodialysis Patients After One Year 2Health News:NxStage Reports Sustained Reduction in Clinical Depressive Symptoms for Daily Home Hemodialysis Patients After One Year 3Health News:NxStage Reports Sustained Reduction in Clinical Depressive Symptoms for Daily Home Hemodialysis Patients After One Year 4
(Date:1/15/2014)...  According to Millennium Research Group (MRG), the global ... the United States and European transcatheter ... moderately through 2022, with embolization particles representing one ... in drug-eluting beads (DEBs) and radioembolization spheres in ...
(Date:1/15/2014)... NEW YORK , Jan. 15, ... new market research report is available ... Global Markets and Technologies for ... on Routes of Administration ...
(Date:1/14/2014)... HAMILTON, N.J. , Jan. 14, 2014 InformEx, ... buyers and sellers of high-value chemistry, will hold the 30 ... Miami Beach Convention Center from January 21-24. ... than 3,500 attendees from top pharmaceutical, fine chemical and specialty ...
Breaking Medicine Technology:US and European Transcatheter Embolization and Occlusion Device Market to Surpass $1.6 Billion by 2022 2US and European Transcatheter Embolization and Occlusion Device Market to Surpass $1.6 Billion by 2022 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 2Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 4Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 5Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 6Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 7Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 8Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 9Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 10Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 11Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 12Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 13Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 14Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 15Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 16Media Advisory: InformEx 2014 Events & Speaker Lineup for 30th Edition Conference in Miami Beach 2
... BD (Becton, Dickinson and Company) (NYSE: BDX ... of its third fiscal quarter 2011 earnings conference call on ... will issue a press release detailing the quarter,s earnings earlier ... along with related slides, will be accessible through BD,s website ...
... Va., July 8, 2011 The Amerigroup Foundation recently ... the Rx Partnership to benefit the Rockbridge Area Free ... organization that works to provide uninsured Virginians with access ... broker to access and distribute free bulk prescription medications ...
Cached Medicine Technology:Amerigroup Foundation Presents Grant to Rx Partnership 2
... An APTT-based assay for the detection ... poor anticoagulant response to activated protein C ... an estimation of the anticoagulant function in ... risk associated with inherited and acquired APC ...
Inquire...
Each Uro-Safe® vinyl leg bag is hand-tested for defects through each phase of the manufacturing process and packaged individually in a sterile, easy, peel-open pouch with two latex leg straps....
... valve is enclosed in a ... the valve from being accidentally ... or reclining positions. The valve ... free ensuring uninterrupted flow and ...
Medicine Products: