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Low Blood Sugar Events Increase Dementia Risk in Elderly Patients With Type 2 Diabetes, Kaiser Permanente Study Finds
Date:4/14/2009

es not benefit all patients and may cause harm to some, especially to patients with more longstanding diabetes, with previous cardiovascular disease, and possibly to those with a history of severe hypoglycemia, Selby said. For these patients, the harms of tight glycemic control, in the form of cardiovascular disease and death, may outweigh any possible benefits, he added.

In view of these three trials, recent recommendations from the American Heart Association and the American College of Cardiology have urged that treatment be individualized and that caution be exercised to prevent severe hypoglycemia. The guidelines further emphasize the critical importance of blood pressure control, lipid or cholesterol control, smoking cessation, and use of aspirin, said Selby.

Additional researchers on the Kaiser Permanente study include: Andrew Karter, Ph.D., and Charles P. Quesenberry Jr., Ph.D., both with the Kaiser Permanente Division of Research; and Kristine Yaffe, MD, with geriatric psychiatry at the UCSF-affiliated Veterans Affairs Medical Center.

About the Kaiser Permanente Division of Research (http://www.dor.kaiser.org/)

The Kaiser Permanente Division of Research conducts, publishes, and disseminates epidemiologic and health services research to improve the health and medical care of Kaiser Permanente members and the society at large. It seeks to understand the determinants of illness and well-being and to improve the quality and cost-effectiveness of health care. Currently, DOR's 400-plus staff is working on more than 250 epidemiological and health services research projects.

About Kaiser Permanente Research

Kaiser Permanente's eight research centers comprise one of the largest research programs in the United States and engage i
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SOURCE Kaiser Permanente
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