Navigation Links
Low Blood Sodium Predicts Mortality in PAH Patients

Routine measurement could be a vital indicator for treating narrowing of lung arteries

FRIDAY, June 20 (HealthDay News) -- New research shows that people with chronically high blood pressure in the blood vessels of the lungs and low serum sodium levels have a very high mortality rate.

Low blood sodium -- called hyponatremia, or HN -- is a known indicator of advanced left heart failure, but the new study from the University of Pennsylvania researchers now connects it with right heart failure in patients with pulmonary arterial hypertension (PAH).

PAH, a syndrome marked by narrowing of the arteries in the lungs, causes the right ventricle of the heart to work harder to pump blood into the lungs for reoxygenation.

"This is the first study to show the powerful prognostic significance of low blood sodium in these patients," lead author Dr. Paul R. Forfia, a medical director of the Pulmonary Hypertension Program at the Hospital of the University of Pennsylvania, said in a prepared statement.

The findings, published in a June issue of American Journal of Respiratory and Critical Care Medicine, are important, because serum sodium is a routine lab measurement that could now be a vital indicator in PAH patients.

In a study of PAH patients, 85 percent in the group with HN died during a two-year follow-up period, compared with just 19 percent of the group without HN. The median survival time was less than nine months. All the patients with sodium concentration levels right around the low-end of the minimum recommended level died, while all those at least slightly above the minimum lived.

The two groups in the study were similar in age, sex, ethnicity and body mass index, but those with HN had significantly poorer kidney function and three times the likelihood of lower extremity edema along with echocardiogram indications of significantly worse right heart function. During two years of follow up, hospitalization for HN patients occurred twice as often, mostly for right heart failure.

"Thus, serum sodium has important implications regarding right heart dysfunction, clinical right heart failure, and patient outcome, and should not be overlooked in the clinical assessment of patients with PAH," Forfia said.

More information

The National Heart, Lung, and Blood Institute has more about pulmonary arterial hypertension.

-- Kevin McKeever

SOURCE: American Thoracic Society, news release, June 13, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Specific antagonism lowers blood pressure
2. Restricting Blood Flow May Help Heart Bypass Patients
3. FDA Updates Prescription Guidelines for Blood Thinner
4. Doctors Often Miss High Blood Pressure in Kids
5. Back to School Means Return of School Blood Drives
6. Blood-flow detector software show promise in preventing brain damage
7. FDA Approves New Roche West Nile Virus Blood Screening Test
8. Australian-led international study shows blood pressure drugs cut death rate in type 2 diabetes
9. Laser blasts viruses in blood
10. Study Demonstrates Marteks Algal DHA Oil Improves Blood Triglyceride Lipid Levels
11. LifeMasters Provides Tips for Maintaining a Healthy Blood Cholesterol Level
Post Your Comments:
(Date:6/27/2016)... ... June 27, 2016 , ... ... patient payment industry today announced its strategic partnership with Connance, a healthcare ... , The two companies’ proven, proprietary technology combine to provide health systems, ...
(Date:6/26/2016)... ... 26, 2016 , ... Pixel Film Studios Released ProSlice Levels, a Media Slicing ... their videos a whole new perspective by using the title layers in ProSlice ... , ProSlice Levels contains over 30 Different presets to choose from. FCPX ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery services, can ... Surgery and to Dr. Russell Peckham for medical and surgical dermatology. , Dr. Dorsey ... cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was under ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as ... City area —Johnson is one of the first doctors to perform the treatment. ...
(Date:6/24/2016)... , ... June 24, 2016 , ... June 19, 2016 ... dangers associated with chronic pain and the benefits of holistic treatments, Serenity Recovery ... are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Research and Markets has announced the ... to 2022" report to their offering. ... patients with kidney failure, it replaces the function of kidneys ... blood and thus the treatment helps to keep the patient ... Increasing number of ESRD patients & substantial ...
(Date:6/23/2016)... 2016 Roche (SIX: RO, ROG; OTCQX: RHHBY) ... Elecsys BRAHMS PCT (procalcitonin) assay as a dedicated testing ... With this clearance, Roche is the first IVD company ... for sepsis risk assessment and management. PCT ... PCT levels in blood can aid clinicians in assessing ...
(Date:6/23/2016)... , June 23, 2016 Bracket , ... launch its next generation clinical outcomes platform, Bracket eCOA (SM) ... held on June 26 – 30, 2016 in ... first electronic Clinical Outcome Assessment product of its kind to ... #715. Bracket eCOA 6.0 is a flexible platform ...
Breaking Medicine Technology: