Navigation Links
Loss of Key Blood Cell Gene Tied to Anemia, Animal Research Suggests
Date:11/7/2012

WEDNESDAY, Nov. 7 (HealthDay News) -- Scientists have discovered a new gene, known as Atpif1, that enables the body to make hemoglobin -- the protein in red blood cells that is responsible for transporting oxygen in the blood.

In their study, researchers from Brigham and Women's Hospital in Boston revealed that loss of this critical blood cell gene seems to result in severe anemia or a lower than normal number of red blood cells or levels of hemoglobin. They said that the findings provide new insight into anemia and could lead to the development of improved treatments for the condition.

Using zebrafish, the researchers cloned the Atpif1 gene, which regulates the production of hemoglobin during the formation of red blood cells. They found the loss of this gene results in severe anemia.

After examining data on the human form of Atpif1, first study author Dhvanit Shah, of the hospital's division of hematology, and colleagues said the gene is essential for normal red blood cell differentiation. Any deficiency in this gene, they added, might play a role in certain human diseases.

Older people and women of childbearing age are at greater risk for anemia. Babies and children also are at risk for the condition due to iron deficiency from their diet or lead poisoning, the researchers said.

The study was published in the Nov. 7 online edition of the journal Nature.

More information

The U.S. National Library of Medicine has more about anemia.

-- Mary Elizabeth Dallas

SOURCE: Brigham and Women's Hospital, news release, Nov. 7, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. High Blood Pressure Often Missed in Young Adults: Study
2. Standard Dose of Blood Thinner May Not Be Best for All Patients
3. Daily Aspirin May Help Those at Risk for Recurrent Blood Clots
4. Higher Blood Pressure May Harm the Middle-Aged Brain, Study Finds
5. RI Hospital: Near-complete blood flow restoration critical for best outcomes in stroke
6. Automated calls help patients in under-developed countries manage blood pressure, U-M study finds
7. Routine blood test predicts prognosis in aggressive skin cancer
8. Fast-Food Breakfast Sandwiches May Slow Down Blood Flow: Study
9. New options for ease and accuracy in extraction of rare cells or separating blood
10. Year of Taking Risky Blood Thinners May Be Unnecessary After Stent Surgery
11. COPD patients experience poorer sleep quality and lower blood oxygen levels
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Loss of Key Blood Cell Gene Tied to Anemia, Animal Research Suggests
(Date:6/25/2016)... ... ... The temporary closing of Bruton Memorial Library on June 21 due to a possible lice ... overlooked aspect of head lice: the parasite’s ability to live away from a human host, ... a necessary one in the event that lice have simply gotten out of control. , ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as ... City area —Johnson is one of the first doctors to perform the treatment. ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Those who have ... these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as ... Michigan, has released tools for healthy coping following a traumatic event. , Trauma sufferers ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Global law ... magazine’s 2016 Legal Elite. The attorneys chosen by their peers for this recognition are ... , Seven Greenberg Traurig Shareholders received special honors as members of this year’s Legal ...
(Date:6/24/2016)... , ... June 24, 2016 , ... People across the ... Genome magazine’s Code Talker Award, an essay contest in which patients and their families ... to be presented at the 2016 National Society of Genetic Counselors (NSGC) Annual Education ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... -- Research and Markets has announced the addition ... report to their offering. ... The World Market for Companion Diagnostics covers the world ... in the report includes the following: , ... by Region (N. America, EU, ROW), 2015-2020 , World ...
(Date:6/24/2016)... 24, 2016   Pulmatrix, Inc ., (NASDAQ: ... inhaled drugs, announced today that it was added to ... its comprehensive set of U.S. and global equity ... an important milestone for Pulmatrix," said Chief Executive Officer ... of our progress in developing drugs for crucial unmet ...
(Date:6/24/2016)... , June 24, 2016  Arkis BioSciences, a ... invasive and more durable cerebrospinal fluid treatments, today ... The Series-A funding is led by Innova Memphis, ... and other private investors.  Arkis, new financing will ... and the market release of its in-licensed Endexo® ...
Breaking Medicine Technology: