Navigation Links
Loss of Key Blood Cell Gene Tied to Anemia, Animal Research Suggests
Date:11/7/2012

WEDNESDAY, Nov. 7 (HealthDay News) -- Scientists have discovered a new gene, known as Atpif1, that enables the body to make hemoglobin -- the protein in red blood cells that is responsible for transporting oxygen in the blood.

In their study, researchers from Brigham and Women's Hospital in Boston revealed that loss of this critical blood cell gene seems to result in severe anemia or a lower than normal number of red blood cells or levels of hemoglobin. They said that the findings provide new insight into anemia and could lead to the development of improved treatments for the condition.

Using zebrafish, the researchers cloned the Atpif1 gene, which regulates the production of hemoglobin during the formation of red blood cells. They found the loss of this gene results in severe anemia.

After examining data on the human form of Atpif1, first study author Dhvanit Shah, of the hospital's division of hematology, and colleagues said the gene is essential for normal red blood cell differentiation. Any deficiency in this gene, they added, might play a role in certain human diseases.

Older people and women of childbearing age are at greater risk for anemia. Babies and children also are at risk for the condition due to iron deficiency from their diet or lead poisoning, the researchers said.

The study was published in the Nov. 7 online edition of the journal Nature.

More information

The U.S. National Library of Medicine has more about anemia.

-- Mary Elizabeth Dallas

SOURCE: Brigham and Women's Hospital, news release, Nov. 7, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. High Blood Pressure Often Missed in Young Adults: Study
2. Standard Dose of Blood Thinner May Not Be Best for All Patients
3. Daily Aspirin May Help Those at Risk for Recurrent Blood Clots
4. Higher Blood Pressure May Harm the Middle-Aged Brain, Study Finds
5. RI Hospital: Near-complete blood flow restoration critical for best outcomes in stroke
6. Automated calls help patients in under-developed countries manage blood pressure, U-M study finds
7. Routine blood test predicts prognosis in aggressive skin cancer
8. Fast-Food Breakfast Sandwiches May Slow Down Blood Flow: Study
9. New options for ease and accuracy in extraction of rare cells or separating blood
10. Year of Taking Risky Blood Thinners May Be Unnecessary After Stent Surgery
11. COPD patients experience poorer sleep quality and lower blood oxygen levels
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Loss of Key Blood Cell Gene Tied to Anemia, Animal Research Suggests
(Date:9/30/2014)... Visit Pam and Steve’s quiet home in the ... a loving couple facing the most monumental challenge of ... Steve was diagnosed with ALS – more commonly known ... the couple’s second wedding anniversary. Pam is now ... “Care, Support & ALS,” that’s part of the ...
(Date:9/30/2014)... (PRWEB) September 30, 2014 A highlight ... Optics (AMO) at the American Academy of Ophthalmology meeting ... LASIK surgeon Jeffrey Martin, MD on the ... is the Managing Partner of North Shore Eye Care ... SUNY Stony Brook. , This year’s 118th Annual American ...
(Date:9/30/2014)... News) -- Herceptin is the best drug treatment for ... remain the standard of care for that type of ... trial. HER2-positive breast cancers tend to be more ... the Mayo Clinic. For the study, more than ... or Tykerb (lapatinib) in addition to standard chemotherapy. ...
(Date:9/30/2014)... September 30, 2014 The St. Louis ... SLUCare Physician Group, comprised of more than 500 physicians, ... number of initiatives. With the recent addition of ... strengthening its market footprint to better respond to the ... , SLPA is a physician-led clinically integrated network (CIN) ...
(Date:9/30/2014)... Francisco, California (PRWEB) September 30, 2014 ... expected to reach USD 8,020.1 million by 2020, ... Research, Inc. Growing demand for personalized medicine and ... diagnostic technologies are expected to be key factors ... Moreover, the growing global base of geriatric population ...
Breaking Medicine News(10 mins):Health News:Hospice Provides Care and Support to Patients and Family Caregivers with ALS 2Health News:Global Laser Technology Leader Selects Jeffrey Martin, MD To Address Colleagues During International Symposium In Chicago 2014 2Health News:Global Laser Technology Leader Selects Jeffrey Martin, MD To Address Colleagues During International Symposium In Chicago 2014 3Health News:St. Louis Physician Alliance Expands Network and Market Footprint with Recent Addition of SLUCare Physician Group 2Health News:Global Molecular Diagnostics Market Is Expected To Be Worth $8,020.1 million by 2020: Grand View Research, Inc. 2Health News:Global Molecular Diagnostics Market Is Expected To Be Worth $8,020.1 million by 2020: Grand View Research, Inc. 3Health News:Global Molecular Diagnostics Market Is Expected To Be Worth $8,020.1 million by 2020: Grand View Research, Inc. 4Health News:Global Molecular Diagnostics Market Is Expected To Be Worth $8,020.1 million by 2020: Grand View Research, Inc. 5Health News:Global Molecular Diagnostics Market Is Expected To Be Worth $8,020.1 million by 2020: Grand View Research, Inc. 6
... has invited best-selling author and noted physician Abraham Verghese to ... and Human Values at 7:30 p.m., Monday, Oct. 24 at ... Indian-American immigrant to the United States, Dr. Verghese,s varied professional ... India studies program at UH," said Lois Zamora, chair of ...
... Phase III trial of RTS,S*, published online today in the ... malaria vaccine candidate to provide young African children with significant ... and tolerability profile. The results were announced today at the ... in Seattle, Washington. Half the world,s population is at ...
... HealthDay Reporter , MONDAY, Oct. 17 (HealthDay ... conventional Pap tests as a cervical cancer screening tool ... The U.S. Preventive Services Task Force ... researchers are now seeking to fine-tune these guidelines. The ...
... (IAN Project) launches a national survey to study the ... (ASD). Bullying, a pervasive problem among youth, has attracted ... lasting, and sometimes tragic, effects on children and teenagers ... be especially vulnerable targets due to their social deficits ...
... (HealthDay News) -- Experts at the American Academy of Pediatrics ... for sudden infant death syndrome (SIDS). Those are two ... SIDS guidelines. Since 1992, when the AAP recommended that ... SIDS has declined sharply in the United States, according to ...
... Cypress, CA, October 18, 2011 Technology has radically ... this more evident than in the field of gynecologic ... teaching minimally invasive treatment for women,s health problems, will ... tools among the hundreds of postgraduate courses and practice ...
Cached Medicine News:Health News:Dr. Abraham Verghese to give John P. McGovern Lecture on Oct. 24 2Health News:Malaria vaccine candidate, RTS,S reduces the risk of malaria by half in African children 2Health News:Malaria vaccine candidate, RTS,S reduces the risk of malaria by half in African children 3Health News:Pap Test Still Best for Cervical Cancer Screening, Experts Say 2Health News:Pap Test Still Best for Cervical Cancer Screening, Experts Say 3Health News:National survey will measure how bullying impacts children with autism 2Health News:Breast-Feeding, Vaccinations Lower SIDS Risk, Experts Say 2Health News:Innovations in minimally invasive surgery and education are highlights of 40th AAGL Global Congress 2Health News:Innovations in minimally invasive surgery and education are highlights of 40th AAGL Global Congress 3Health News:Innovations in minimally invasive surgery and education are highlights of 40th AAGL Global Congress 4
(Date:9/30/2014)... Inc. ( www.synapsebiomedical.com ) announced today it has ... its NeuRx DPS® System for ALS patients.  The ... requirement was implanted over a month and a ... is the only medical device approved by the ... device that obtained approval at the end of ...
(Date:9/30/2014)... Netherlands , Sept. 30, 2014  eHealth, ... phone storage and access of this information, has ... Slot , however, that has not translated into ... http://photos.prnewswire.com/prnh/20140929/149122 Photo - http://photos.prnewswire.com/prnh/20140929/149123 ... the past few years developing MWD® Health Manager ...
(Date:9/30/2014)... 30, 2014 It is evident from the industry ... not performing upto expectations due to the lack of promotional ... the intake of omega-3 fatty acids. Among omega-3 ingredient sources ... oil, attributed to the large vegetarian population in ... fatty acid (PUFAs) ingredients is in growth stage of its ...
Breaking Medicine Technology:Synapse Biomedical Announces the Early Completion of Enrollment in the FDA Post Approval Study for ALS Patients 2Synapse Biomedical Announces the Early Completion of Enrollment in the FDA Post Approval Study for ALS Patients 3MWD Challenges the Big eHealth Players With New Software for Your Smartphone 2Omega-3 Polyunsaturated Fatty Acids (PUFAs) - An Indian Market Overview 2
... FRANCISCO, Oct. 29 Medivation, Inc. (Nasdaq: MDVN ... webcast with management to discuss third quarter 2010 financial results ... at 4:30 p.m. Eastern Time. A press release for the ... markets close on November 5, 2010. Interested ...
... N.Y., Oct. 29 Henry Schein, Inc. (Nasdaq: ... to office-based practitioners, today reported record financial results for the ... the third quarter of 2010 were $1.9 billion, an increase ... consists of 16.4% growth in local currencies and a decline ...
Cached Medicine Technology:Henry Schein Reports Record Third Quarter Results 2Henry Schein Reports Record Third Quarter Results 3Henry Schein Reports Record Third Quarter Results 4Henry Schein Reports Record Third Quarter Results 5Henry Schein Reports Record Third Quarter Results 6Henry Schein Reports Record Third Quarter Results 7Henry Schein Reports Record Third Quarter Results 8Henry Schein Reports Record Third Quarter Results 9Henry Schein Reports Record Third Quarter Results 10Henry Schein Reports Record Third Quarter Results 11
Each handle is designed to fit a specific trephine size. For use in performing free-hand uniform donor buttons....
Each handle is designed to fit a specific trephine size....
Each handle is designed to fit a specific trephine size....
Each handle is designed to fit a specific trephine size....
Medicine Products: