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Losing Weight After Diabetes Diagnosis can Prevent Diabetes-Related Disease, Kaiser Permanente Study Finds
Date:8/11/2008

First Clinical Study to Show Benefits Remain Even If Patients Regain Weight

PORTLAND, Ore., Aug. 12 /PRNewswire/ -- People who lose weight soon after a diagnosis of type 2 diabetes have better control of their blood pressure and blood sugar, and are more likely to maintain that control even if they regain their weight, according to a Kaiser Permanente study published online in Diabetes Care, the American Diabetes Association journal.

This is the first clinical study to show that benefits remain even if patients regain their weight. The study followed more than 2,500 adults with type 2 diabetes for four years. Those who lost weight within an average of 18 months after diagnosis were up to twice as likely to achieve their blood pressure and blood sugar targets as those who didn't lose weight. Those benefits can prevent diabetes-related heart disease, blindness, nerve and kidney damage, and death.

"Our study shows that early weight loss can reduce the risk factors that so often lead to diabetes complications and death," says Dr. Adrianne Feldstein, MD, MS, the study's lead author, a practicing physician and an investigator at Kaiser Permanente's Center for Health Research in Portland, Ore. "We've known for a long time that weight loss is an important component in diabetes treatment and prevention. Now it appears there may be a critical window of opportunity following diagnosis in which some lasting gains can be achieved if people are willing to take immediate steps toward lifestyle changes."

More than 20 million Americans have type 2 diabetes and most of them are overweight or obese.

Funded by the National Institutes of Health, the four-year study conducted by Kaiser Permanente in Oregon and Washington followed 2,574 patients with type 2 diabetes between 1997 and 2002. Scientists followed the weight gain and loss patterns of these patients for three years, and then in the fourth year compared glucose control tests and blood pressur
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SOURCE Kaiser Permanente
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