Navigation Links
Looping genes may hold a key to understanding breast cancer
Date:4/9/2008

Another piece of the puzzle that is breast cancer has been found by University of Queensland researchers.

Dr Melissa Brown, from UQ's School of Molecular and Microbial Sciences, and her team have discovered how a particular gene associated with breast cancer behaves, which may lead to better testing for the debilitating disease.

Dr Brown and Dr Juliet French at UQ, together with their colleagues at The University of Oxford, studied the BRCA1 gene and found that it exists in a looped formation.

Our studies suggest that BRCA1 looks a bit like a bow when the gene is switched off, and that part of this bow' disappears when the gene is switched on, Dr Brown said.

Interestingly, the shape of the bow changes in different breast cancer cells, raising the possibility that this gene looping may contribute to the cancer process.

She said ongoing studies would identify the specific DNA sequences and DNA binding molecules involved in BRCA1 gene looping.

The status of these sequences in a larger cohort of breast cancer patients will also be determined, she said.

This information may lead to more sensitive pre-symptomatic testing for breast cancer and the identification of new therapeutic targets.


'/>"/>

Contact: Andrew Dunne
communications@uq.edu.au
61-733-652-802
Research Australia
Source:Eurekalert

Page: 1

Related medicine news :

1. Pathway links inflammation, angiogenesis and breast cancer
2. Traffic Fumes Plus Genes Boosts Kids Asthma Risk
3. New Database to Help Speed Search for Bipolar Disorder Genes
4. Is Perfect Pitch All in the Genes?
5. Discovery suggests location of genes for breast density, a strong risk factor for breast cancer
6. Genes Boost Risk for Rheumatoid Arthritis, Lupus
7. The genes involved in rheumatoid arthritis identified
8. If you think cancer genes are simple, you dont know JAK
9. Test for lung cancer looks for discomforting quiet among protective genes
10. Hushed Genes Might Mean Higher Lung Cancer Risk
11. EURYI project to understand how the brain wires during embryogenesis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2015)... Sheltering Arms announced that it has acquired ... Mother Hale Learning Center meets a tremendous need in ... Arms will begin operating the site immediately and all ... center. , Opened in 2006, the Mother Hale Learning ... years, many of whom come from high-need backgrounds. Guided ...
(Date:5/4/2015)... MT (PRWEB) May 04, 2015 New ... with Care to Care, LLC to manage outpatient advanced ... help New West Medicare ensure its members are provided ... unnecessary radiation. , Working closely with New West Medicare’s ... promoting the safe use of advanced imaging and provide ...
(Date:5/4/2015)... Elisabeth Rosenthal’s article* on “balance ... showed the healthcare fraternity as well as patients ... downside of balance billing. In definition, balance billing ... a patient for the difference between what the ... the provider chooses to charge. Rosenthal’s article talks ...
(Date:5/4/2015)... 2015 In response to the ... Task Force (USPSTF), Strategic Radiology® (SR®) fully aligns ... Obstetricians and Gynecologists (ACOG), the American College Of ... Cancer Society (ACS), American College of Radiology (ACR), ... recommend regular screening mammography for women beginning at ...
(Date:5/4/2015)... World T.E.A.M. Sports’ best-attended Face of ... last decade arrived in this historic Civil War community ... from the Pentagon in Arlington, Virginia. The annual ride ... able-bodied participants work together to successfully complete the journey. ... commitment and sacrifices by military veterans in their defensive ...
Breaking Medicine News(10 mins):Health News:Sheltering Arms Acquires the Mother Hale Learning Center 2Health News:New West Medicare Partners with Care to Care, LLC to Manage Advanced Imaging Services 2Health News:Out of Network Balance Billing Without Being Viewed as Fraud 2Health News:Out of Network Balance Billing Without Being Viewed as Fraud 3Health News:Strategic Radiology® Takes Unified Stance Against New USPSTF Guidelines 2Health News:Strategic Radiology® Takes Unified Stance Against New USPSTF Guidelines 3Health News:Strategic Radiology® Takes Unified Stance Against New USPSTF Guidelines 4Health News:Strategic Radiology® Takes Unified Stance Against New USPSTF Guidelines 5Health News:Gettysburg Welcomes Arriving Face of America Riders with Gala Celebration 2Health News:Gettysburg Welcomes Arriving Face of America Riders with Gala Celebration 3Health News:Gettysburg Welcomes Arriving Face of America Riders with Gala Celebration 4
... a product containing the drug estazolam, which might make the ... // ,Estazolam belongs to benzodiazepines class of drugs, ... it may have a number of side effects like loss ... not legal to sell it in Canada. ,Hence, try ...
... There has been a major outbreak of pneumonia in the ... // ,The outbreak in the Downtown Eastside has ... month. ,In a November 30 memo, David Butcher, ... staff that the Vancouver outbreak was severely limiting the availability ...
... become an integral part of the cocktail of drugs consumed by ... ice are marijuana, ketamine, heroin and other illicit drugs. ,Ice ... when they have report to work. ,After excessive stimulation by ... which they usually smoke ice to get over it. ,Paul ...
... taken from primary tumor biopsies is highly associated with ... to researchers who// say this protein profile could help ... is likely to metastasize. ,In the December ... of one unidentified protein and under-expression of another is ...
... by team of senior scientists warns that many tests of drugs ... prototype medicine will work on humans. ,The British Medical ... have found that animal studies agreed with human trials in just ... that the high-profile London drug trial that left six men ill ...
... Health urges people with history of unprotected sex to ... local HIV transmission.// The announcement being the first case ... officials, on Thursday uncovered two clusters of HIV infections, ... samples by government scientists. They said that both the ...
Cached Medicine News:Health News:Researchers Find Two Biomarkers With Potential to Predict Breast Cancer Spread 2Health News:Researchers Find Two Biomarkers With Potential to Predict Breast Cancer Spread 3Health News:Researchers Find Two Biomarkers With Potential to Predict Breast Cancer Spread 4Health News:Many Drug Tests on Animals are Badly Flawed, a Study Warns 2
(Date:5/4/2015)... 2015 Unchained Labs, a refreshingly new biologic ... PEGS conference and launches the UNit — the first ... The Essential Protein Engineering Summit takes place in ... The UNit lets drug discovery researchers look at more ... Its 7 applications, 144 sample a day throughput and ...
(Date:5/4/2015)... , May 4, 2015 The Pharmacy ... Survey, which confirmed that pharmacy has shifted toward a ... active pharmacists and managers, there is an incredible opportunity ... in the next decade. In a ... site, Essential Insights , Eden Sulzer, director ...
(Date:5/4/2015)... 4, 2015  Verus Healthcare, Inc. recently completed its ... Care Club in 2012.  Since that original acquisition, the ... medical equipment (DME) industry by 1,000%.  Verus Healthcare now ... supply needs and processes nearly 14,000 new orders per ... years ago, the systems and processes weren,t in place ...
Breaking Medicine Technology:Unchained Labs Lets the UNit Loose 2Cardinal Health Expert Discusses Latest Research On Gender Gap In Pharmacy 2Cardinal Health Expert Discusses Latest Research On Gender Gap In Pharmacy 3Verus Healthcare Celebrates 1,000% Growth on Third Anniversary 2
... Cyberonics, Inc. (Nasdaq: CYBX ) today announced ... Browne, Chief Financial Officer, will present at the 22nd Annual ... November 30, 2010 at 1:30 PM ET.  The conference session ... will be presented.  Piper Jaffray will host a webcast of ...
... /PRNewswire-FirstCall/ -- AVANIR ... the pricing of an underwritten public offering of 20,000,000 shares ... per share.  The offering is expected to close on or ... addition, AVANIR has granted the underwriters a 30-day option to ...
Cached Medicine Technology:Cyberonics to Present at 22nd Annual Piper Jaffray Health Care Conference 2AVANIR Pharmaceuticals Announces Pricing of Public Offering of Common Stock 2AVANIR Pharmaceuticals Announces Pricing of Public Offering of Common Stock 3
The Biopro All Poly cup is a uniquely designed UHMWPE acetabular cup....
The Plasmacup SC satisfies two important requirements: high primary stability and a low friction bearing surface....
The cementless biomEx cup can be used with both cemented and cementless femoral stems....
The Secur-Fit cups incorporate enhancements derived from years of clinical, radiographic, and implant retrieval observations....
Medicine Products: