Navigation Links
Long-term calcium-channel blocker use for hypertension associated with higher breast cancer risk
Date:8/5/2013

Long-term use of a calcium-channel blocker to treat hypertension (high blood pressure) is associated with higher breast cancer risk, according to a report published by JAMA Internal Medicine, a JAMA Network publication.

Antihypertensive medications are the most commonly prescribed class of drugs in the United States and in 2010 totaled an estimated 678 million filled prescriptions, Christopher I. Li, M.D., Ph.D., of the Fred Hutchinson Cancer Research Center, Seattle, and colleagues write in the study background.

"Evidence regarding the relationship between different types of antihypertensives and breast cancer risk is sparse and inconsistent, and prior studies have lacked the capacity to assess impacts of long-term use," the study notes.

The population-based study in the three-county Seattle-Puget Sound metropolitan area included women ages 55 to 74 years: 880 of the women had invasive ductal breast cancer, 1,027 had invasive lobular breast cancer and 856 of them had no cancer and served as the control group. Researchers measured the risk of breast cancer and examined the recency and duration of use of antihypertensive medications.

According to the results, current use of calcium-channel blockers for 10 or more years was associated with higher risks of ductal breast cancer (odds ratio [OR], 2.4) and lobular breast cancer (OR, 2.6). The relationship did not vary much based on the type of calcium-channel blockers used (short-acting vs. long-acting or dihydropyridines vs. non-dihydropyridines). Other antihypertensive medications - diuretics, β-blockers and angiotensin II antagonists were not associated with increased breast cancer risk, the results indicate.

"While some studies have suggested a positive association between calcium-channel blocker use and breast cancer risk, this is the first study to observe that long-term current use of calcium-channel blockers in particular are associated with breast cancer risk. Additional research is needed to confirm this finding and to evaluate potential underlying biological mechanisms," the study concludes.


'/>"/>

Contact: Kristen Woodward
kwoodwar@fhcrc.org
206-667-5095
The JAMA Network Journals
Source:Eurekalert

Related medicine news :

1. Therapy for severe vasculitis shows long-term effectiveness
2. Fertility therapy not associated with long-term cardiovascular disease
3. Increased Risk of Heart Disease Associated With Long-Term Obesity Article Published by Health News Wires
4. Baseball players enjoy successful long-term results after elbow surgery
5. Health info exchange: Short-term growth, but long-term concerns
6. Long-term cannabis use may blunt the brains motivation system
7. Non-Compliance With the Affordable Care Act (ACA) Remains a Risk for Long-Term Care Facilities
8. Long-term study reports deep brain stimulation effective for most common hereditary dystonia
9. Long-term apremilast demonstrates continued efficacy in patients with psoriatic arthritis
10. No increased risk of infection for long-term sex partners of people with HPV-related oral cancers
11. Integrated stroke care system results in fewer deaths, discharges to long-term care facilities
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/7/2016)... ... 07, 2016 , ... “Fred Rides a Train” allows readers to tag along ... “Fred Rides a Train” is the creation of published author, Janet Morrison, who has ... in Michigan. The "Fred, the Dog" series is her first attempt at writing for ...
(Date:12/7/2016)... ... December 07, 2016 , ... The Business ... Summit in Reston, VA on March 21-22, 2017. This premier event features business ... experiences from a cross-section of industries such as financial services, insurance, healthcare, manufacturing, ...
(Date:12/7/2016)... CA (PRWEB) , ... December 07, 2016 , ... NuevaCare, ... Francisco Peninsula region, is proud to announce new city-specific pages as part of its ... for the elderly, they often look, first, for local agencies serving their city. The ...
(Date:12/6/2016)... ... December 06, 2016 , ... People with Parkinson’s disease and ... a type of MRI, according to a study appearing online in the journal ... system characterized by tremors or trembling and stiffness in the limbs, impaired balance ...
(Date:12/6/2016)... Los Angeles, CA (PRWEB) , ... December 06, ... ... to suffer from erectile dysfunction because of a higher risk of serious health ... article on Star2.com. Dr. Peiman Soleymani of Beverly Hills Periodontics & ...
Breaking Medicine News(10 mins):
(Date:12/6/2016)... , Dec. 6, 2016  "Blood Tests ... cancers announced ....." The Diagnostic, Monitoring and ... in cancer diagnostics is occurring using in vitro ... new company with impressive backing, has announced a ... technology is moving faster than the market. New ...
(Date:12/6/2016)... 6, 2016 The pen needles market is ... USD 1.65 billion in 2016, growing at a CAGR ... 2021. Over the years, the pen needles market ... to the growing demand for safety injections in the ... of safety pen needles with an aim to reduce ...
(Date:12/6/2016)... Dec. 6, 2016  BTL Aesthetics today announced ... its BTL Vanquish ME device was effectively redesigned ... to the targeted tissue. The result: Significantly better ... with BTL Vanquish ME versus BTL Vanquish. ... network and their patients with the most highly-advanced ...
Breaking Medicine Technology: