Navigation Links
Long-term antibiotic treatment for Q fever causes weight gain
Date:4/14/2014

Scientists have unearthed still more evidence that antibiotics can contribute to obesity. Research published ahead of print in the journal Antimicrobial Agents and Chemotherapy suggests that patients on long-term antibiotic treatment gained weight and had significant changes in their gut microbiota.

The study, led by Didier Raoult, of Aix-Marseille University, Marseille, France, followed 48 patients who were being treated long-term with doxycycline and hydroxychloroquine for Q fever, and 34 control subjects. Nearly one quarter of the treated patients gained anywhere from two to 13 kg (five to 30 lbs), while none of the controls exhibited weight gain. Patients typically received treatment for 18 months.

"Doxycycline and hydroxychloroquine treatment exhibited a reproducible effect on the community structure of the gastrointestinal microbiota, with treated patients presenting significantly lower concentrations of beneficial bacteria, Bacteroidetes, Firmicutes, and Lactobacilli," says coauthor Angelakis Emmanouil, of Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), CNRS, Marseille.

"Reproducible" refers to the fact that the same effect is seen in all the treated patients with weight gain. That strengthens the connection between the diminished numbers of bacterial species and the weight gain.

The finding that one in four patients had weight gain suggests that particular subgroups of patients treated for Q fever are vulnerable to weight gain. In research published last year, Raoult and others showed that the vulnerable subgroups could be predicted by the composition of their gut microbiota prior to antibiotic treatment.

The investigators conclude that their results highlight the need for reduced calorie diets for patients undergoing long-term antibiotic treatment, especially with doxycycline.

Q fever causes endocarditis, an infectious inflammation of the inner lining
'/>"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Vaccine yielded encouraging long-term survival rates in certain patients with NSCLC
2. Long-term neuropsychological impairment is common in acute lung injury survivors
3. Supporting LGB children may influence their long-term health, BU study finds
4. Optimal care of bariatric surgery patients vital for long-term health and well-being
5. Many Primary Care Docs Dont Know Long-Term Effects of Chemo: Survey
6. Study says children exposed to tobacco smoke face long-term respiratory problems
7. More Research Points to Long-Term Ills With Bone Drugs
8. Long-term ICS use reduces pleural effusion in patients with CAP
9. Group B streptococcal meningitis has long-term effects on childrens developmental outcomes
10. Long-Term Salty Diets Tied Again to High Blood Pressure
11. Long-term cancer survivors struggle to keep regular work hours
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2015)... (PRWEB) May 04, 2015 San ... cutting ceremony at their brand new, 13,700 square foot ... The new building will not only provide fertility treatment ... will also offer community and educational events to a ... facility is located next door to their current Carmel ...
(Date:5/4/2015)... New West Medicare is excited to announce they ... outpatient advanced imaging services for its members. Care to ... are provided the right test at the right time ... West Medicare’s physicians and hospitals, Care to Care will ... and provide an objective basis for informed evidence-based clinical ...
(Date:5/4/2015)... May 04, 2015 Dr. Richard Champagne, ... been chosen to receive the America’s Best Dentist Award, ... Champagne’s selection as a top dentist is a reflection ... continuing education and his compassion for his patients. , ... who exemplify excellence in their field. These nominees are ...
(Date:5/4/2015)... Gettysburg, Pennsylvania (PRWEB) May 04, 2015 ... bicycle and hand cycle ride in the last decade ... after riding 110 miles in two days from the ... national non-profit saw 581 registered disabled and able-bodied participants ... Face of America recognizes and honors the commitment and ...
(Date:5/4/2015)... Food Cost Calculator ” was featured on NewsWatch as part ... latest and coolest applications on the market for iOS, Android, ... expert, conducted the app review and shared with viewers how ... food costs. , The restaurant industry is a vital cornerstone ... estimated 1.8 trillion dollar impact on the US economy. But ...
Breaking Medicine News(10 mins):Health News:San Diego Fertility Center Hosted a Ribbon Cutting Ceremony at Its New, Expanded Facility 2Health News:San Diego Fertility Center Hosted a Ribbon Cutting Ceremony at Its New, Expanded Facility 3Health News:New West Medicare Partners with Care to Care, LLC to Manage Advanced Imaging Services 2Health News:New Jersey Dentist Dr. Richard Champagne Nominated for America’s Best Dentist Award 2Health News:Gettysburg Welcomes Arriving Face of America Riders with Gala Celebration 2Health News:Gettysburg Welcomes Arriving Face of America Riders with Gala Celebration 3Health News:Gettysburg Welcomes Arriving Face of America Riders with Gala Celebration 4Health News:An Application to Manage a Successful Restaurant Was Featured on NewsWatch Television 2
... HALL, N.C., EXTON, Pa. and SAN DIEGO, Nov. ... southeastern US,provider of oncology equipment sales and service, ... alliance with Radiology Oncology Systems, Inc.,(ROS), an oncology ... Acceletronics, Inc., a US provider of oncology equipment ...
... Charged with Illegally Distributing over 12 Million Narcotic ... United States,Attorney Matt M. Dummermuth announced today that ... distribute controlled substances through an,Internet pharmacy and with ... in an Indictment filed today in United States ...
... Calif., Nov. 8 InteKrin Therapeutics, Inc.,a privately-held ... commercialization of novel drugs for the treatment of,diabetes ... M.D. has joined the company as Chief Medical ... senior management team and will be,responsible for the ...
... NEW YORK, Nov. 8 Wolf Popper LLP has ... MDT ) and,certain of its officers and directors ... Minnesota, on behalf of investors who purchased,Medtronic common stock ... 15, 2007 (the "Class Period"). This is the first ...
... (Unaudited) ... For the three months ended For the six months ended ... 2007 2006 ... $3,069,762 $2,315,781 $7,940,405 $7,836,896, Gross profit ...
... for Continued Efforts on $1 Billion ... Life Sciences Legislation Future of Biotechnology Featured: RNA, Nanomedicine, ... 2007 Editor,s Note: Reporters can listening to company presentations at, http://massbio.org/events/mass_opps/press.php ... available on Friday on the ...
Cached Medicine News:Health News:RS&A, Inc. Announces It Has Joined Radiology Oncology Systems, Inc. (ROS) and Acceletronics, Inc. in a Strategic Alliance to Better Serve Its Customers in the Southeastern US 2Health News:RS&A, Inc. Announces It Has Joined Radiology Oncology Systems, Inc. (ROS) and Acceletronics, Inc. in a Strategic Alliance to Better Serve Its Customers in the Southeastern US 3Health News:$40 Million Forfeiture Sought in Nation-Wide Internet Pharmacy Case 2Health News:InteKrin Therapeutics, Inc. Appoints Former Amgen Clinical Development Executive Chief Medical Officer 2Health News:InteKrin Therapeutics, Inc. Appoints Former Amgen Clinical Development Executive Chief Medical Officer 3Health News:Wolf Popper Announces Filing of Securities Class Action Lawsuit Against Medtronic Inc. - MDT 2Health News:Wolf Popper Announces Filing of Securities Class Action Lawsuit Against Medtronic Inc. - MDT 3Health News:MagStar Technologies, Inc. Announces Third Quarter 2007 Results 2Health News:MagStar Technologies, Inc. Announces Third Quarter 2007 Results 3Health News:Biotech Company Builder Papadopoulos Says Investment in Innovation Needed to Advance Drug Pipeline at Massachusetts Biotechnology Council's Ninth Annual MASS Opportunities Investment Conference 2Health News:Biotech Company Builder Papadopoulos Says Investment in Innovation Needed to Advance Drug Pipeline at Massachusetts Biotechnology Council's Ninth Annual MASS Opportunities Investment Conference 3Health News:Biotech Company Builder Papadopoulos Says Investment in Innovation Needed to Advance Drug Pipeline at Massachusetts Biotechnology Council's Ninth Annual MASS Opportunities Investment Conference 4
(Date:5/4/2015)... CARLSBAD, Calif. , May 4, 2015  Isis ... an exclusive license agreement with Bayer HealthCare (Bayer) to ... of thrombosis. Under the terms of the agreement, Isis ... near-term payments, including an immediate $100 million up-front payment ... program following a Phase 2 study in patients with ...
(Date:5/4/2015)... NEW YORK , May 4, 2015  FireflySci Inc., the newest member of the ... months after launch, they have turned the cuvette industry on its head by offering scientists amazing ... http://photos.prnewswire.com/prnh/20150501/213243LOGO Photo - http://photos.prnewswire.com/prnh/20150501/213244 ... ... ...
(Date:5/4/2015)... 2015 Intarcia Therapeutics, Inc. ... into the newly created role of Chief ... pharmaceutical executive with world-class experience – most recently ... service at industry leaders such as Pfizer and ... range of therapeutic areas, including: cardiovascular, metabolic, oncology, ...
Breaking Medicine Technology:Isis Pharmaceuticals Licenses ISIS-FXI Rx to Bayer to Develop and Commercialize for the Prevention of Thrombosis 2Isis Pharmaceuticals Licenses ISIS-FXI Rx to Bayer to Develop and Commercialize for the Prevention of Thrombosis 3Isis Pharmaceuticals Licenses ISIS-FXI Rx to Bayer to Develop and Commercialize for the Prevention of Thrombosis 4Isis Pharmaceuticals Licenses ISIS-FXI Rx to Bayer to Develop and Commercialize for the Prevention of Thrombosis 5New Cuvette Manufacturer Delivers Fast, Easy Solutions for Even the Hardest Cuvette Experiments 2New Cuvette Manufacturer Delivers Fast, Easy Solutions for Even the Hardest Cuvette Experiments 3Intarcia Names Top Commercial Expert Michael Williams As COO; Will Chair Commercial Committee And Lead ITCA 650 Launch In U.S. 2Intarcia Names Top Commercial Expert Michael Williams As COO; Will Chair Commercial Committee And Lead ITCA 650 Launch In U.S. 3Intarcia Names Top Commercial Expert Michael Williams As COO; Will Chair Commercial Committee And Lead ITCA 650 Launch In U.S. 4
Latex agglutination slide test for the qualitative and semi-quantitative in vitro determination of CRP in serum....
For the quantitative in vitro determination of Apolipoprotein A-1 in human serum....
For the quantitative determination of apolipoprotein B (apo B) in serum and plasma....
The GGT method used on the Dimension clinical chemistry system is an in vitro diagnostic test intended for the quantitative determination of g-glutamyl transferase activity in serum and plasma...
Medicine Products: