Navigation Links
Long-Term Use of Antibiotic May Help Those With COPD
Date:5/21/2013

TUESDAY, May 21 (HealthDay News) -- Thousands of Americans, many of them smokers or ex-smokers, suffer from the lung condition known as chronic obstructive pulmonary disease (COPD). Now a new study finds that patients placed on the common antibiotic azithromycin may be able to cut down on hospitalizations due to flare-ups of the disease.

"Given that exacerbations of COPD can be life-threatening, prevention of such events is critical," said Victoria Richards, assistant professor of medical science at Quinnipiac University in Hamden, Conn. Use of the antibiotic might also cut down on the need for doctor's office visits and boost patients' quality of life, said Richards, who was not involved in the study.

The research was presented Tuesday at the annual meeting of the American Thoracic Society in Philadelphia.

COPD is a progressive disease involving bronchitis and emphysema, often tied to smoking, that makes it hard for patients to breathe.

In the new study, researchers compared how patients fared on a 12-month regimen of the drug versus patients who were given a dummy medication.

"COPD patients who have been hospitalized for a respiratory event are at particularly high risk for re-hospitalization," study lead author Dr. Fernando Martinez said in a meeting news release.

"We wanted to examine whether chronic azithromycin therapy might provide a benefit in these patients," said Martinez, who is director of pulmonary diagnostic services at the University of Michigan Health System, in Ann Arbor.

To assess treatment effectiveness, the researchers looked at data from a prior study conducted by the COPD Clinical Research Network.

Patients in that study had either suffered a so-called "acute exacerbation" of COPD in the year leading up to the study or were using supplemental oxygen at the beginning of the study.

For one year the patients randomly were assigned to receive either a daily dose of 250 milligrams of azithromycin or a placebo.

The result: Compared with the placebo group, patients taking the antibiotic were able to benefit from longer gaps between hospitalizations.

"We found that there was a significant delay from the first respiratory-related hospitalization to the next one among those treated with azithromycin," Martinez said. He said the finding also held for re-hospitalizations that were due to any cause, not just respiratory issues.

One expert said the findings warrant further investigation, but pointed out that the history of antibiotic use in people with respiratory disease has had its ups and downs.

"A number of years ago, it was reported that Ketak, an antibiotic in the erythromycin family, was helpful in reducing exacerbations in asthma," said Dr. Len Horovitz, a pulmonary specialist at Lenox Hill Hospital in New York City. "[However], there were other problems with this antibiotic, and it was discontinued."

He called the new findings with azithromycin "promising," but added a caveat: "It was recently found that azithromycin is contraindicated in patients with cardiac arrhythmia, which [can] occur in COPD, so these factors must be viewed with caution."

For his part, Martinez said more research will need to be done to confirm the findings, and experts note that findings presented at medical meetings are typically considered preliminary until published in a peer-reviewed journal.

More information

Find out more about COPD at the U.S. National Heart, Lung, and Blood Institute.

-- Alan Mozes

SOURCES: Victoria Richards, Ph.D., assistant professor, medical sciences, Frank H. Netter M.D. School of Medicine, Quinnipiac University, Hamden, Conn; Len Horovitz, M.D., pulmonary specialist, Lenox Hill Hospital, New York City; news release, American Thoracic Society annual meeting, Philadelphia


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Long-term outcomes in patients with advanced coronary artery disease are better than expected
2. Erectile Dysfunction Tied to Long-Term Narcotic Use in Men
3. Long-term use of prescription painkillers for back pain linked to erectile dysfunction in men
4. BMA Affordable Assisted Living Community to Host Informational Program on Long-Term Care Insurance
5. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Offers New Unlimited Support To Dieters, Making the Transfer to Long-term Improved Health Easier
6. A "FAST" Response to Stroke Can Reduce Long-Term Damage
7. Chickenpox Shot Provides Long-Term Protection, Study Finds
8. Varicella vaccine has long-term effectiveness against chicken pox
9. New mechanism for long-term memory formation discovered
10. False-Positive Mammograms Can Trigger Long-Term Distress
11. Breast Cancer Radiation Has Long-Term Heart Effects: Study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Long-Term Use of Antibiotic May Help Those With COPD
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits ... terms of the latter, setting the bar too high can result in disappointment, perhaps ... slow progress toward their goal. , Research from PsychTests.com reveals that ...
(Date:6/24/2016)... Michigan (PRWEB) , ... June 24, 2016 , ... June ... about the dangers associated with chronic pain and the benefits of holistic treatments, ... individuals who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is ...
(Date:6/24/2016)... ... ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida attorneys are recognized ... this recognition are considered among the top 2 percent of lawyers practicing within the ... this year’s Legal Elite Hall of Fame: Miami Shareholders Mark D. Bloom, Burt ...
(Date:6/24/2016)... ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, ... minimum wage raise to $12 an hour by 2020 and then adjusting it yearly to ... value of the minimum wage, assure the wage floor does not erode again, and make ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute ... Dr. Barry M. Weintraub as a prominent plastic surgeon and the network’s newest ... world, and the most handsome men, look naturally attractive. Plastic surgery should be ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... Research and Markets has announced the addition of the ... report to their offering. ... failure, it replaces the function of kidneys by removing the ... the treatment helps to keep the patient body,s electrolytes such ... Increasing number of ESRD patients & substantial healthcare expenditure on ...
(Date:6/23/2016)... June 23, 2016  In a startling report released today, ... residents by lacking a comprehensive, proven plan to eliminate prescription opioid ... ranking of how states are tackling the worst drug crisis in ... states – Kentucky , New Mexico ... . Of the 28 failing states, three – ...
(Date:6/23/2016)... LOS ANGELES , June 23, 2016 /PRNewswire/ ... (NASDAQ: CAPR ), a biotechnology company ... first-in-class therapeutics, today announced that patient enrollment in ... progrEssion in Duchenne) has exceeded 50% of its ... its enrollment in the third quarter of 2016, ...
Breaking Medicine Technology: