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Long Term Supply of Osteocel(R) Plus Solidified Without Ownership of Processing Facility
Date:3/30/2009

f Osteocel Plus. AlloSource is one of the nation's largest tissue providers and has already started supplying Osteocel Plus. AlloSource has been working to scale up its production since last summer and NuVasive expects the AlloSource supply relationship to provide an efficient and consistent stream of supply. NuVasive will not assume ownership of the Osiris tissue processing facility.

NuVasive reiterates its previous guidance of $28 million in Osteocel Plus revenue in 2009 with no change in profitability targets. NuVasive notes that the transfer of processing will support its ability to meet or exceed 2009 Osteocel Plus sales goals and fuel anticipated revenue growth to $100 million and beyond.

About NuVasive

NuVasive is a medical device company focused on the design, development and marketing of products for the surgical treatment of spine disorders. The Company's product portfolio is focused on applications in the over $4.6 billion U.S. spine fusion market. The Company's current principal product offering includes a minimally disruptive surgical platform called Maximum Access Surgery, or MAS(R), as well as a growing offering of biologics, cervical and motion preservation products.

The MAS platform offers advantages for both patients and surgeons such as reduced surgery and hospitalization time and faster recovery. MAS combines three categories of current product offerings: NeuroVision(R) a proprietary software-driven nerve avoidance system; MaXcess(R) a unique split-blade design retraction system; and specialized implants, like SpheRx(R) and CoRoent(R), that collectively minimize soft tissue disruption during spine surgery while allowing maximum visualization and surgical reproducibility. NuVasive's product offering is also focused on cervical internal fixation products and its R&D pipeline emphasizes both MAS and motion preservation. NuVasive's Biologic product portfolio includes FormaGraft
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SOURCE NuVasive, Inc.
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