Navigation Links
Long-Term Statin Use Best Way to Cut Cardiovascular Deaths
Date:1/12/2010

Emphasis needed on getting patients to keep taking their meds, researchers say

TUESDAY, Jan. 12 (HealthDay News) -- A 50 percent increase in patients adhering to long-term treatment with cholesterol-lowering statins could prevent twice as many deaths from heart attack and stroke, British researchers say.

It's estimated that only about half of patients prescribed statins to prevent cardiovascular disease are still taking them five years later, according to background information in the analysis.

The researchers reviewed published studies on the sustained use of statins by patients to calculate an assumed average of their capacity to continue treatment over 10 years. The team then used cholesterol and blood pressure data from more than 38,000 patients in Australia to calculate the likelihood of developing cardiovascular disease and the advantages of preventive strategies.

The study authors then calculated patient risk scores according to three scenarios: using the current U.K. National Institute for Health and Clinical Excellence (NICE) guidelines, which recommend that anyone with a 20 percent or greater risk of heart attack or stroke over the next 10 years be prescribed a statin; increased adherence to statin treatment; and lowering the threshold for starting on statins to increase the number of patients taking the drugs.

On the basis of risk factors among the Australian patients, the researchers calculated that 5,390 new cases of cardiovascular disease and 710 related deaths would occur over 10 years. They also determined that 24 percent of patients would be eligible for statin treatment under NICE guidelines. If half (4,563) of those patients fully complied with statin treatment, an estimated 174 cases of cardiovascular disease and 70 deaths would be prevented.

Expanding treatment criteria to allow for 6,991 patients to take statins over the long term would prevent an additional 70 cases of cardiovascular disease and 18 deaths. Improving long-term statin compliance among 6,971 patients would prevent an additional 91 cases of cardiovascular disease and stave off 37 related deaths -- about twice as many as expanding treatment criteria to increase the number of patients eligible to take the drugs.

It's no surprise that focusing on patients most at risk should yield more impressive results, said Dr. Amir Shroufi, who is currently at the Cambridge Institute of Public Health in the United Kingdom, and colleagues.

"However, the magnitude of the difference is notable. And it serves to emphasize the need to find more effective means of increasing adherence -- especially over the long term," the study authors wrote.

The study was released online Jan. 12 in advance of publication in an upcoming print issue of the Journal of Epidemiology and Community Health.

More information

The U.S. Food and Drug Administration has more about statins.



-- Robert Preidt



SOURCE: BMJ Journals, news release, Jan. 11, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Smoking may strongly increase long-term risk of eye disease
2. Long-Term Fatigue Plagues Cancer Survivors
3. Dont Ignore Tough or Long-Term Stomach Pain
4. Shaking may cause brain damage and serious long-term effects to infants
5. Sexual function affected by stem cell transplant according to long-term study
6. Smoking can harm the long-term effects of some oral surgery procedures
7. Childhood Obesity Epidemic a Long-Term Challenge
8. Conseco to Host Follow-Up Long-Term Care Conference Call
9. New Report Finds Information Technology Essential But Not Sufficient in Long-Term Care
10. No Link Between Amateur Boxing, Long-Term Brain Damage
11. No strong evidence linking amateur boxing with long-term brain injury
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/22/2017)... ... April 22, 2017 , ... Ecommerce sales have grown ... estimated to be $394.9 billion. The consequences of rapid innovation and growth are ... limits of technology, it is every business and individual’s job to give something back ...
(Date:4/22/2017)... ... 22, 2017 , ... PharmacyChecker.com released its first International Prescription ... 70% when buying medication online from Canadian pharmacies verified in the PharmacyChecker Verification ... countries. The report (chart below) compares U.S. and foreign prices for 20 of ...
(Date:4/22/2017)... , ... April 22, 2017 , ... The San Juan Capistrano summer camp ... parenting report outlining the need for summer camps to provide physical activities for all campers. ... Physical Activity In Summer Camps , With an increase in specialty camps that focus on ...
(Date:4/21/2017)... ... ... broad access to life-saving drugs and rewarding the innovators who develop those drugs often ... , That was the message from Dana Goldman, PhD, Leonard D. Schaeffer Chair and ... who served as the keynote speaker for Western University of Health Sciences’ Ray Symposium ...
(Date:4/21/2017)... (PRWEB) , ... April 21, 2017 , ... ... professor Christopher Salas-Wright finds that youth violence is declining—and at noteworthy rates. Between ... relative proportion of young people involved in violence in the United States. The ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... Research and Markets has announced the addition of the ... Outlook, Growth Trends, Key Players, Competitive Strategies and Forecasts, 2014 ... ... US$ 7,167.6 Mn in 2015, and is expected to reach ... 5.6% from 2016 to 2024. The global ...
(Date:4/20/2017)... Research and Markets has announced the ... Market Analysis By Service (Manufacturing, Research), By Country, (Brazil, Mexico, ... report to their offering. ... The Latin American pharmaceutical contract manufacturing services market ... Low drug registration cost in Latin American countries and ...
(Date:4/19/2017)... The Mobile X-Ray product segment is the most ... the forecast period Mobile X-Ray segment is the ... X-Ray devices market, which is estimated to be valued at ... CAGR of 7% over the forecast period. Mobile X-Ray segment ... US$ 100 Mn in 2017 over 2016. The segment,s revenue ...
Breaking Medicine Technology: