Navigation Links
Long-Term Lead Exposure Linked to Heart Deaths
Date:9/8/2009

Current OSHA guidelines are probably inadequate, researchers say

TUESDAY, Sept. 8 (HealthDay News) -- Exposure to lead over a lifetime may increase the risk of dying from heart disease, new research shows.

Researchers analyzed lead concentrations in the blood and bones of 868 mostly white men from the Boston area who participated in a veterans' aging study.

The men, whose average age was 67 at the start of the study, had lead concentrations in their blood and the bones of the patella (kneecap) and tibia (shin) measured over a nine-year period. During the course of the study, 241 died.

Researchers found that men who had the highest concentrations of lead in their bones had a six times greater chance of dying from cardiovascular disease than men with the lowest concentrations.

Men with the highest levels of lead had a 2.5 times greater chance of dying from all causes than men with the lowest levels.

"Cumulative exposure to lead, even in an era when current exposures are low, represents an important predictor of cardiovascular death," said study author Marc Weisskopf, an assistant professor of environmental health and epidemiology at the Harvard School of Public Health in Boston. "The findings with bone lead are dramatic. It is the first time we have had a biomarker of cumulative exposure to lead, and the strong findings suggest that it is a more critical biomarker than blood lead."

The study appears in the Sept. 8 issue of Circulation.

Typically, lead exposure is measured through blood samples. For instance, the Occupational Safety and Health Administration (OSHA) and the National Health and Nutrition Examination Surveys use blood to measure lead.

But blood, because it has a half life of about 30 days, reveals recent exposure. To determine cumulative exposure, bone is the better method, according to the study.

Bone has a half life ranging from years to decades, including eight years in the knee cap and possibly decades in the shin. To determine bone lead concentration, researchers used a technique similar to a chest X-ray.

Researchers said the link to cardiovascular disease underscores the need for regulatory bodies and surveillance agencies to track potential sources of lead exposure.

"Researchers studying cardiovascular deaths worldwide have generally not considered lead as one of the risk factors that contributes to the risk of death from cardiovascular disease," Weisskopf said.

Overall, study participants had blood levels of lead that were slightly higher than the average of similar U.S. men.

While few if any participants in the study were occupationally exposed to lead, occupations such as construction and painting put men at higher risk.

The current OSHA standards, which are based on blood lead levels and permit up to 40 micrograms of lead per deciliter, are probably inadequate, Weisskopf said.

Before being banned in the mid-1990s, leaded gasoline was a major source of U.S. environmental lead exposure.

Current sources of exposure are chipping, flaking lead in paint in older homes, water pipes in older homes, lead in food and drinking water and hobbies that involve casting ammunition, toy soldiers, fishing weights, lead in solder for making stained glass and some ceramic glazes.

More information

The American Academy of Family Physicians has more on lead exposure.



--Jennifer Thomas



SOURCE: American Heart Association, news release, Sept. 8, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. LIVALO(R) Demonstrates Sustained, Long-Term Efficacy and Tolerability in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia
2. Long-term tamoxifen use increases risk of an aggressive, hard to treat type of second breast cancer
3. New research: Consumption of sugar substitutes assists in long-term weight control
4. Long-term exercise, healthy eating habits in young adults: U-M study
5. Attendance on Demand, Inc. Hosts Free Webinar Top 5 Tools to Control Labor Costs for Long-Term Healthcare Professionals 2:30pm EDT August 26, 2009
6. Long-Term Care Leader Joins 3 in 4 Need More Campaign to Promote LTC Protection for All
7. New Health Reform Campaign Will Support Long-Term Care for All, Because 3 in 4 Need More
8. MU expert offers tips for finding the best long-term care
9. LG Electronics Introduces New Flat-Panel HDTVs Designed Specifically for Long-Term Care Facilities
10. Long-term health and social outcomes for neuroblastoma survivors
11. Blood Transfusions Not Linked to Long-Term Problems
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Long-Term Lead Exposure Linked to Heart Deaths
(Date:5/5/2016)... ... , ... TransWipe Volume 3 is a set of 30 professional transition animations ... between two video clips to instantly add a unique transition to any Final Cut ... and orientation options. TransWipe Volume 3 is a Final Cut Pro X exclusive plugin. ...
(Date:5/5/2016)... (PRWEB) , ... May 05, 2016 , ... While the ... being paid to the impact our aging population has on communities and resources. Aging ... adults plan for and face age-related challenges. , Aging Life Care is a ...
(Date:5/5/2016)... , ... May 05, 2016 , ... ... overall select performance in the industry’s gold standard KLAS Performance Report, ... Epic Consulting report assessed organizations that specialize in consulting services for electronic health ...
(Date:5/5/2016)... , ... May 05, 2016 , ... ... long-acting injectables (LAIs), today announced a development collaboration with the Australian critical ... serious mental disorders such as schizophrenia. , LAI medicines can offer improved therapeutic ...
(Date:5/5/2016)... ... 05, 2016 , ... Textile Exchange is excited to announce the ... review. The stakeholder review is an important opportunity for interested parties to give input ... to the wool industry., The RWS is intended to be a global benchmark for ...
Breaking Medicine News(10 mins):
(Date:5/5/2016)... , May 6, 2016 ... of liver disorders along with rise in obesity ... drugs in the coming few years. The NASH ... last five years on account of rising number ... is a large, un-tapped market with no FDA ...
(Date:5/5/2016)... reported initial promising results in animal trials of its Zika vaccine candidates. ... ... ... ... analysis identified the highest gene Replikin Counts in Zika history back to 1946 (1). ...
(Date:5/5/2016)... May 5, 2016  Endo International plc (NASDAQ: ... that Brian Lortie , President, U.S. Branded ... position upon the appointment of a successor. Mr. ... U.S. Pharmaceuticals business with responsibility for all strategic, ... strategy and portfolio development, commercial operations, managed markets, ...
Breaking Medicine Technology: