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Local Heart Doctors First in Nation to Announce Active Investigation of Red Wine (Resveratrol) Pills, Issue Consumer Precautions
Date:7/9/2009

h as dizziness, fatigue, headaches and sore Achilles tendons, which are the most commonly experienced.

Red wine pills commonly feature resveratrol, a molecule that has produced strikingly positive effects in animal studies. Resveratrol inhibits blood clots, reduces inflammation and favorably alters cholesterol, among its many beneficial properties.

Red wine molecules pre-condition the heart

Dr. Lebowitz says, in animals, resveratrol has been shown to produce what is called a pre-conditioning effect for the heart. Normally a protective enzyme called heme-oxygenase is rapidly produced following a heart attack to limit damage to heart muscle tissue caused by the release of iron. In animal studies, resveratrol has been shown to trigger the production of heme-oxygenase prior to a heart attack and therefore limit damage caused by the event, he says.

Dr. Lebowitz says the pre-conditioning effect is only achieved when proper doses of resveratrol are employed. Too little and there is no benefit, and too much resveratrol and the damage caused by a heart attack will be worsened. "This is why we want to guide our patients, rather than leave them to navigate in the use of these red wine dietary supplements on their own," he says.

Gene activation

Resveratrol is fast becoming a household word as it now widely extolled as a potential longevity molecule. Resveratrol and other small molecules found in red wine can enter living cells and influence genetic machinery. One widely studied gene pathway, activated by resveratrol, is the Sirtuin1 gene, known as a survival gene. The current idea is to develop pills that will mimic the effects of a calorie-restricted diet, which is known to double the lifespan of all living organisms.

Doctors at the Advanced Cardiology Institute have chosen to dispense red wine pills directly to patients to better monit
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SOURCE Advanced Cardiology Institute
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