Navigation Links
Lloyd Wright's Alternative Medicine Has One of its Hepatitis C Viral Inhibitors Given Boost as Scripps Study Peptides Effectiveness
Date:11/18/2009

packaging of the HCV RNA genome.

The Core of the Matter
Core, the most conserved protein among all HCV genotypes, plays several essential roles in the viral cycle in the host cell; studies have suggested that these core-core or core-other protein interactions can modulate various functions including signaling, apoptosis or programmed cell death, lipid metabolism, and gene transcription.

The core protein is particularly important in the assembly of the hepatitis C nucleocapsid, an essential step in the formation of infectious viral particles; the nucleocapsid is the viral genome protected by a protein coat – the capsid. This core protein plays an essential role in the HCV cycle during assembly and release of the infectious virus, as well as disassembly of viral particles upon entering host cells.

Looking closely at the core interaction with itself, Strosberg developed several novel quantitative assays or tests for monitoring these protein-protein interactions with the specific goal of identifying inhibitors of the core dimerization, which would block virus production.

"People have been dreaming about inhibiting protein-protein interactions, as a new El Dorado for finding novel drug targets," says Strosberg, "but few conclusive studies have emerged, except in the virus-host area."

Inhibition of HCV Production
The new research, however, led to the discovery of two peptides that inhibited HCV production by 68 percent and 63 percent, respectively; a third related peptide showed 50 percent inhibition. When added to HCV-infected cells, each of the three peptides blocked release but not replication of infectious virus; viral RNA levels were reduced by seven fold. Strosberg notes that the efficacy of small molecules like these can often be improved over initial levels.

"After we'd finished our work, we learned that Frank Chisari – one of the leading experts on HCV who work
'/>"/>

Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved  

Page: 1 2 3 4 5

Related medicine news :

1. Lloyd Wright's Alternative Medicine Marketing Only Blueberry Extract with 45% of Hepatitis C Inhibitor Proanthocyanidin
2. Lloydspharmacy Reveals Hayfever Misery to Hit One in Two People by 2060
3. Darwins Kim Lloyd to Speak on Panel at American Hospital Association Solutions Roundtable, June 3, 2009
4. Lloyd I. Miller III Announces Voting Intentions for United American Healthcares Annual Meeting
5. Ricky Tomlinson Joins Lloydspharmacy Against Coronary Heart Disease
6. InterCure Secures Nationwide Distribution Agreement With Lloyds Pharmacy Group
7. Delaware Hospice Honors President and CEO Susan D. Lloyd, MSN, RN
8. When East meets West: Why consumers turn to alternative medicine
9. Alternative to Warfarin May Cut Risk of Bleeding
10. Stem Cells May Offer Alternative to Lung Transplants
11. SleepApneaUSA.net Announced An Immediate Alternative Sleep Apnea Solution In Response To The NTSB's Sleep Apnea Testing Recommendations
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Lloyd Wright's Alternative Medicine Has One of its Hepatitis C Viral Inhibitors Given Boost as Scripps Study Peptides Effectiveness
(Date:12/17/2014)... -- Expectant parents should leave prenatal picture-taking to medical ... Use of ultrasound imaging and heartbeat monitors to get ... agency warns. "Although there is a lack ... and heartbeat monitors, prudent use of these devices by ... FDA biomedical engineer, said in an agency news release. ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, ... America, and work commitment is a big reason why, new ... said Dr. Mathias Basner, an assistant professor of sleep and ... of Medicine. A time-use survey of nearly 125,000 Americans, ... main activity exchanged for sleep. Short sleepers -- those who ...
(Date:12/15/2014)... 15, 2014 South Florida’s leading urgent care ... can be a daze of hassle, hustle, and bustle that ... decking halls, to burns when making special meals and heartburn ... can happen at any time. To prevent this season of ... made a list of helpful and healthful holiday tips to ...
(Date:12/15/2014)... News) -- Expert pilots process visual information more efficiently ... better decisions during landings, a new study shows. ... pilots to master, and 36 percent of all airplane ... final approach and landing. Researchers monitored the brain ... pilots while they were at the controls of a ...
(Date:12/15/2014)... 15, 2014 At the leading, long-established ... AutismOne and Focus Autism will welcome ... research on the effects of toxins to children’s health, ... information. , Luminaries such as Dr. Lucija Tomljenovic ... with esteemed, credentialed colleagues of the United States to ...
Breaking Medicine News(10 mins):Health News:FDA Warns Against Fetal 'Keepsake' Videos 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3Health News:Study Shows Why Expert Pilots Are Experts 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 3
... survivors are living longer and there is an urgent ... health-related quality of life and need for psychosocial services, ... Adolescent and Young Adult Oncology ( JAYAO ), ... JAYAO is the Official Journal of the ...
... beach on the minds of millions of winter-weary people, ... to determine when levels of disease-causing bacteria in beach ... who dig or play in the sand. The report ... . Tomoyuki Shibata and Helena M. Solo-Gabriele explain ...
... ALERT: Additional video resources, including excerpts from an interview with ... on the Mayo Clinic News Blog . JACKSONVILLE, ... of the first health care institutions in the United States to ... (GERD) . The condition, also known as acid reflux disease ...
... April 11, 2012 -- Approximately 200,000 people in the ... to achieve significant weight loss. Recent reports indicating that ... type 2 diabetes than medication alone is likely to ... weight, diabetes, and other comorbid conditions, healthcare providers caring ...
... Regular walking can help reduce fatigue in some pancreatic cancer ... white men and women aged 66 or 67 who underwent ... before they were discharged from the hospital. One group ... a walking or exercise routine. The other group was told ...
... HealthDay Reporter , TUESDAY, April 10 (HealthDay News) ... before radiation doses were lowered, may be at greater risk ... of the brain, a new study suggests. The research ... about 1 percent of people. It,s also possible that dental ...
Cached Medicine News:Health News:Unique approach needed to accurately assess health of young adult cancer survivors 2Health News:Mayo Clinic offers newly approved treatment for acid reflux disease 2Health News:Short Walks May Ease Fatigue in Pancreatic Cancer Patients 2Health News:Dental X-Rays May Be Linked to Benign Brain Tumors 2Health News:Dental X-Rays May Be Linked to Benign Brain Tumors 3
(Date:12/17/2014)... RALEIGH, N.C. , Dec. 17, 2014 ... and Integrated Clinical Trial Services, LLC (ICTS), two ... clinical trials announce that they have formed a ... (i-CTMS). i-CTMS will provide a broad range of ... and medical device companies. i-CTMS will ...
(Date:12/15/2014)... , Dec. 12, 2014 Research and Markets ... of the "Electrocardiogram (ECG) Devices - Global Trends, ... http://photos.prnewswire.com/prnh/20130307/600769 ... US$330 million by 2016. The North America ... global market share while Europe ...
(Date:12/15/2014)... Israel , Dec. 15, 2014  Immune ... announced today that its Board of Directors has elected Mr. ... Teper who continues as Chief Executive Officer of Immune. ... Directors since 2013. Immune,s new Chairman, Mr. ... interest of shareholders and to continue to support the strategic ...
Breaking Medicine Technology:Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 2Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 3Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 2Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 3Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 4Immune Pharmaceuticals Elects Daniel Kazado as New Chairman of the Board. 2Immune Pharmaceuticals Elects Daniel Kazado as New Chairman of the Board. 3Immune Pharmaceuticals Elects Daniel Kazado as New Chairman of the Board. 4
... Kaiser Permanente Hawaii has received the inaugural Pharmacy ... Permanente,s achievement of a 5-star rating on the PQA ... Centers for Medicare and Medicaid Services (CMS) Star Rating ... because it uses publicly available quality data from CMS," ...
... June 2, 2011 Mylan Inc. (Nasdaq: ... Inc. has received final approval from the U.S. Food ... Application (ANDA) for Venlafaxine Hydrochloride (HCl) Extended-release (ER) Capsules, ... (base), the generic version of Wyeth,s Effexor XR® Capsules, ...
Cached Medicine Technology:PQA Recognizes Kaiser Permanente Hawaii for Excellence in Medication Safety 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: