Navigation Links
Living donors fare well following liver transplantation
Date:11/1/2012

Researchers in Japan report that health-related quality of life (HRQOL) for donors following living donor liver transplantation (LDLT) was better than the general Japanese population (the norm). This studyone of the largest to datefound that donors who developed two or more medical problems (co-morbidities) after donation had significantly decreased long-term HRQOL. Full findings are published in the November issue of Liver Transplantation, a journal of the American Association for the Study of Liver Diseases (AASLD).

The shortage of viable donor organs continues to be a critical issue for the transplant community. Livers, in particular, are in short supply, with the Organ Procurement and Transplantation Network (OPTN) reporting that in the U.S. more than 16,000 patients are currently on the waiting list. To ease the shortage of deceased donor organs, transplant specialists are turning to LDLTa widely accepted alternative approach, especially in Japan, where one study shows that close to 6,000 of these procedures were performed by December 2008.

"With LDLTs being performed at increasing rates, it is important to understand the long-term outcomes for living donors," explains lead study author Dr. Yasutsugu Takada with the Ehime University Graduate School of Medicine in Japan. "Our study is the largest to investigate living liver donors' quality of life and to determine potential risk factors following transplantation."

The team contacted 997 living donors who provided a piece of liver for transplantation, which were performed at Kyoto University Hospital between 1990 and 2004. Researchers mailed the 36-item short-form health survey to all donors and 578 (58%) responded. The survey responses are summarized by: the physical component summary, mental component summary, and role/social components by component. A norm-based scoring system was used to report survey results.

Findings indicate that norm-based HRQOL scores for the 367 left- and 211 right-lobe donors were better than the Japanese norm across all time periods. The median post-transplant follow-up period was nearly 7 years. Further analysis determined that decreased HRQOL scores, specifically lower mental health and social functioning, were significantly associated with age of donor, persistence of symptoms, emergence of additional diseases, or other consequences (additional hospital visits, continued work absence) following donation.

Dr. Takada concludes, "Kyoto University Hospital is one of the high volume transplant centers in Asia, as such, we are keenly aware of the necessity and responsibility to report donor long-term QOL. Our findings suggest that careful follow-up and counseling are necessary for donors at risk for poor quality of life."

In a related editorial, Drs. Leona Kim-Schluger and Sander Florman from The Mount Sinai Medical Center in New York highlight that the importance of the Takada et al study is the sheer size of the living donor cohort and the long-term follow-up of donors to evaluate HRQOL. They write, "We must strive to study and comprehend the motivations leading to donation, the financial and economic impact of donation, and learn to alleviate the fears pre and post donation, with the one goal of safely getting the living donors through the donor process medically, surgically, and psychologically."


'/>"/>

Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley
Source:Eurekalert

Related medicine news :

1. Single-port kidney removal through the belly button boosts living-donor satisfaction
2. Survival excellent following living donor liver transplantation for acute liver failure
3. State tax incentives do not appear to increase the rate of living organ donation
4. Older Americans Living Longer, But Becoming More Obese
5. Why living in the moment is impossible
6. Living Without Lies Might Make You Healthier
7. Autumn Birthday Ups Odds of Living to 100: Study
8. Tobacco use more prevalent among African-American adolescents living in public housing communities
9. 300,000 People in U.S. Living With Chagas Disease: Report
10. Mesothelioma Victims Center Now Offers Its Services to Chemical Plant or Power Plant Workers Living with Mesothelioma Including Naming the Best Mesothelioma Attorneys
11. Loneliness, Living Alone Might Shorten Life
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/13/2016)... ... 2016 , ... In its newly released Infusion Therapy Standards ... be used to ensure patient safety when placing an IV catheter. A key ... use of vein visualization technology in patients with difficult venous access or after ...
(Date:2/13/2016)... ... 2016 , ... In the early or “honeymoon” stage of a relationship, couples ... of their way to be romantic, and may exaggerate a strength or two in ... dating profile. , A recent study from Queendom.com , however, suggests that ...
(Date:2/12/2016)... ... February 12, 2016 , ... Mystic Buddha Publishing House presents ... SKies Buddha, the biography of Rama - Dr. Frederick Lenz. , According ... love of a Buddhist teacher for teaching and helping others. Valentine’s Day celebrates ...
(Date:2/12/2016)... (PRWEB) , ... February 12, 2016 , ... ... organization devoted exclusively to funding innovative lymphoma research and serving the lymphoma community ... hosted over 250 members of South Florida’s philanthropic community at its 10th anniversary ...
(Date:2/12/2016)... (PRWEB) , ... February 12, 2016 , ... Each year, ... will be held in Anaheim, CA at the Anaheim Convention Center. Almost 10,000 physical ... see new therapy products in action, learn more about their chosen field and network ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... 2016   Health 2.0 , the premiere showcase ... announced today " 10 Year Global Retrospective ", a ... the past ten years.   --> ... 2.0 has served as the preeminent thought-leader in the ... of technologies, companies, innovators, and patient-activists through an array ...
(Date:2/11/2016)...  NOIT™ Research LLC, a private, leading-edge autism research ... to assist needy families in obtaining one of its ... February 10, 2016 and March 31, 2016, the company ... NOIT is an auditory stimulus that plays a key ... Beth Shier , NOIT Research director. ...
(Date:2/11/2016)... WILMINGTON, N.C. , Feb. 11, 2016 /PRNewswire/ ... a leading provider of custom manufacturing and development ... announces expanded sterile fill-finish capabilities and capacity in ... Substantial growth in demand has driven several recent ... in 2001 it had one filling line with ...
Breaking Medicine Technology: