Navigation Links
Living donors fare well following liver transplantation

Researchers in Japan report that health-related quality of life (HRQOL) for donors following living donor liver transplantation (LDLT) was better than the general Japanese population (the norm). This studyone of the largest to datefound that donors who developed two or more medical problems (co-morbidities) after donation had significantly decreased long-term HRQOL. Full findings are published in the November issue of Liver Transplantation, a journal of the American Association for the Study of Liver Diseases (AASLD).

The shortage of viable donor organs continues to be a critical issue for the transplant community. Livers, in particular, are in short supply, with the Organ Procurement and Transplantation Network (OPTN) reporting that in the U.S. more than 16,000 patients are currently on the waiting list. To ease the shortage of deceased donor organs, transplant specialists are turning to LDLTa widely accepted alternative approach, especially in Japan, where one study shows that close to 6,000 of these procedures were performed by December 2008.

"With LDLTs being performed at increasing rates, it is important to understand the long-term outcomes for living donors," explains lead study author Dr. Yasutsugu Takada with the Ehime University Graduate School of Medicine in Japan. "Our study is the largest to investigate living liver donors' quality of life and to determine potential risk factors following transplantation."

The team contacted 997 living donors who provided a piece of liver for transplantation, which were performed at Kyoto University Hospital between 1990 and 2004. Researchers mailed the 36-item short-form health survey to all donors and 578 (58%) responded. The survey responses are summarized by: the physical component summary, mental component summary, and role/social components by component. A norm-based scoring system was used to report survey results.

Findings indicate that norm-based HRQOL scores for the 367 left- and 211 right-lobe donors were better than the Japanese norm across all time periods. The median post-transplant follow-up period was nearly 7 years. Further analysis determined that decreased HRQOL scores, specifically lower mental health and social functioning, were significantly associated with age of donor, persistence of symptoms, emergence of additional diseases, or other consequences (additional hospital visits, continued work absence) following donation.

Dr. Takada concludes, "Kyoto University Hospital is one of the high volume transplant centers in Asia, as such, we are keenly aware of the necessity and responsibility to report donor long-term QOL. Our findings suggest that careful follow-up and counseling are necessary for donors at risk for poor quality of life."

In a related editorial, Drs. Leona Kim-Schluger and Sander Florman from The Mount Sinai Medical Center in New York highlight that the importance of the Takada et al study is the sheer size of the living donor cohort and the long-term follow-up of donors to evaluate HRQOL. They write, "We must strive to study and comprehend the motivations leading to donation, the financial and economic impact of donation, and learn to alleviate the fears pre and post donation, with the one goal of safely getting the living donors through the donor process medically, surgically, and psychologically."


Contact: Dawn Peters

Related medicine news :

1. Single-port kidney removal through the belly button boosts living-donor satisfaction
2. Survival excellent following living donor liver transplantation for acute liver failure
3. State tax incentives do not appear to increase the rate of living organ donation
4. Older Americans Living Longer, But Becoming More Obese
5. Why living in the moment is impossible
6. Living Without Lies Might Make You Healthier
7. Autumn Birthday Ups Odds of Living to 100: Study
8. Tobacco use more prevalent among African-American adolescents living in public housing communities
9. 300,000 People in U.S. Living With Chagas Disease: Report
10. Mesothelioma Victims Center Now Offers Its Services to Chemical Plant or Power Plant Workers Living with Mesothelioma Including Naming the Best Mesothelioma Attorneys
11. Loneliness, Living Alone Might Shorten Life
Post Your Comments:
(Date:12/1/2015)... (PRWEB) , ... December 01, 2015 , ... ... limb amputations in the United States. Podiatrists are well aware that psychology-based patient ... therapeutic behaviors) are often catastrophic contributors to diseases of the diabetic foot. ...
(Date:12/1/2015)... ... December 01, 2015 , ... Visage accelerates mobile ... wholly owned subsidiary of Pro Medicus Ltd. (ASX: PME), has announced they are ... of North America (RSNA) 2015 annual meeting through December 3 in Chicago, Illinois, ...
(Date:12/1/2015)... ... December 01, 2015 , ... Lutronic, a leading innovator of aesthetic and medical ... the devices for sale in the United States. Clarity is a Superior Dual ... Nd:YAG lasers, into a single platform that is easy to own and operate. ...
(Date:12/1/2015)... Atlanta, GA (PRWEB) , ... December 01, 2015 ... ... manufacturing, supports SACC-GA and SACC-USA through membership and leadership since 2008. ... and Chair for SACC-USA . Gary has spent a significant amount of ...
(Date:12/1/2015)... Charlotte, NC (PRWEB) , ... December 01, 2015 ... ... NHS Foundation Trust on receiving the 2015 HSJ Acute Sector Innovation Award on ... of improving the patient care experience, and propose exciting enhancements to the medical ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... and TELTOW, Germany , December ... (SMI) , a leading global manufacturer of eye and ... has included SMI remote eye trackers as a ... healthcare providers assess concussions, eye sight, and medical and ... -oem technology is part of SMI,s mass-market-ready eye tracking ...
(Date:12/1/2015)... , Dec. 01, 2015 ... the "Drug Delivery Technology Market 2015 - ... --> ) has announced the ... 2015 - Forecast to 2020" report to ... ( ) has announced the addition of ...
(Date:12/1/2015)... ALISO VIEJO, Calif. , Dec. 1, 2015 ... on the prevalence of symptoms for pseudobulbar affect ... uncontrollable outbursts of laughing and/or crying resulting from ... the use of antipsychotic medications in nursing home ... of Geriatric Psychiatry. The study showed that almost ...
Breaking Medicine Technology: