Navigation Links
Liver Cancer Patients May Get Hope

Finding could help identify patients who will benefit from interferon therapy, researchers say

WEDNESDAY, Oct. 7 (HealthDay News) -- A short strand of RNA (microRNA) may help doctors identify liver cancer patients who would benefit from treatment with interferon, say U.S. and Chinese researchers.

"Interferon is an experimental therapeutic agent that has been used for many years to treat cancer patients, but with modest benefit," study first author Junfang Ji, of the liver carcinogenesis section at the U.S. National Cancer Institute's Center for Cancer Research, said in a news release.

"Our findings are exciting because we are rediscovering a drug that may have great potential for patients with a particular genomic profile," added senior author Xin Wei Wang, chief of the liver carcinogenesis section. "Being able to treat patients with an existing drug based on a tumor's genomic profile should improve its efficacy and reduce the cost of treatment."

The study of 241 liver cancer patients found that those with low levels of a microRNA called miR-26 lived about four years less than those with higher expression levels of the microRNA.

A separate analysis of liver tumor samples from 135 patients who had had surgery revealed that those with low levels of miR-26 benefitted from receiving adjuvant interferon therapy. Patients who received interferon lived at least 7.7 years longer than those who didn't receive the drug. Interferon didn't benefit patients with normal levels of miR-26.

The findings suggest that checking miR-26 levels in liver tumors may help determine patient prognosis and identify patients who might benefit from interferon treatment in order to prevent disease relapse, the researchers said.

The study appears in the Oct. 8 issue of the New England Journal of Medicine.

More information

The American Cancer Society has more about liver cancer treatment.

-- Robert Preidt

SOURCE: U.S. National Cancer Institute, news release, Oct. 7, 2009

Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Advanced Age No Bar to Liver Transplant
2. Researchers Find Better Way to Deliver Blood Thinner
3. Federal research plan to determine nanotech risks fails to deliver
4. Liver cancer marker could yield blood test for early detection
5. Blood Marker Might Help Spot Early Liver Cancer
6. Natural Protein Could Help Spot, Treat Liver Cancer
7. Diet Change Can Curb Fatty Liver Disease
8. US FDA Fast Tracks PI-88 for the Treatment of Post Resection Liver Cancer
9. The American Liver Foundation Appoints Rick Smith, a Twenty-Year Veteran of The MS Society, as Chief Executive Officer
10. Re-plumbing liver helps beat cancer
11. Free Prescription Drug Program Uses Internet to Deliver Cards - Offers Assistance to Uninsured
Post Your Comments:
(Date:10/13/2015)... ... October 13, 2015 , ... Sir Grout of Greater Boston donated an expansive, ... of Ronald McDonald House Charities® (RMHC®). This donation was made in an effort to ... Boston since its inception. , “We believe strongly in the Ronald McDonald House Charities, ...
(Date:10/13/2015)... ... October 13, 2015 , ... ... platform, ENGAGE, at HIMSS’s Patient Engagement Summit . HealthAware is a technology ... innovative health programs and interventions via mobile devices that provide a framework for ...
(Date:10/13/2015)... ... October 13, 2015 , ... ... of IBM software products, introduced a new company, RightSensor™ LLC, an Internet of ... communications capability. RightSensor™ provides a fully-managed approach for customers requiring sensor hardware ...
(Date:10/13/2015)... NY (PRWEB) , ... October 13, 2015 , ... NavaFit ... app helps individuals find others to train with, participate in local fitness & ... Store and Google Play. , “As high medical costs drive us to get more ...
(Date:10/13/2015)... ... October 13, 2015 , ... Nordic ... unique health needs of new moms. Postnatal Omega-3, which has been named ... utilizes Nordic Naturals’ exclusive, new, ultra-concentrated omega-3 oil. This breakthrough oil combines ...
Breaking Medicine News(10 mins):
(Date:10/13/2015)... , Oct. 13, 2015 According ... (NCPA) Digest , sponsored by Cardinal Health ... medication and more diversified pharmacy revenue streams are ... pharmacies. NCPA Digest affirms ... and particularly those in underserved inner city and ...
(Date:10/13/2015)... PITTSBURGH , Oct. 13, 2015  Data Science Automation ... the opening of a new branch office in the ... of DSA,s presence in Europe . The ... the increasing demand for local support of customers in the ... , Ph.D., DSA,s UK Branch Manager. "We have had tremendous ...
(Date:10/13/2015)... , Oct. 13, 2015  Nanomedical Diagnostics, ... use in research and diagnostics, announces the completion ... million led by Serra Ventures. ... is providing low-cost, easy-to-use monitoring and diagnostic platforms ... decisions. The funding round will enable the company ...
Breaking Medicine Technology: