Navigation Links
Liver Cancer Patients May Get Hope
Date:10/7/2009

Finding could help identify patients who will benefit from interferon therapy, researchers say

WEDNESDAY, Oct. 7 (HealthDay News) -- A short strand of RNA (microRNA) may help doctors identify liver cancer patients who would benefit from treatment with interferon, say U.S. and Chinese researchers.

"Interferon is an experimental therapeutic agent that has been used for many years to treat cancer patients, but with modest benefit," study first author Junfang Ji, of the liver carcinogenesis section at the U.S. National Cancer Institute's Center for Cancer Research, said in a news release.

"Our findings are exciting because we are rediscovering a drug that may have great potential for patients with a particular genomic profile," added senior author Xin Wei Wang, chief of the liver carcinogenesis section. "Being able to treat patients with an existing drug based on a tumor's genomic profile should improve its efficacy and reduce the cost of treatment."

The study of 241 liver cancer patients found that those with low levels of a microRNA called miR-26 lived about four years less than those with higher expression levels of the microRNA.

A separate analysis of liver tumor samples from 135 patients who had had surgery revealed that those with low levels of miR-26 benefitted from receiving adjuvant interferon therapy. Patients who received interferon lived at least 7.7 years longer than those who didn't receive the drug. Interferon didn't benefit patients with normal levels of miR-26.

The findings suggest that checking miR-26 levels in liver tumors may help determine patient prognosis and identify patients who might benefit from interferon treatment in order to prevent disease relapse, the researchers said.

The study appears in the Oct. 8 issue of the New England Journal of Medicine.

More information

The American Cancer Society has more about liver cancer treatment.



-- Robert Preidt



SOURCE: U.S. National Cancer Institute, news release, Oct. 7, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Advanced Age No Bar to Liver Transplant
2. Researchers Find Better Way to Deliver Blood Thinner
3. Federal research plan to determine nanotech risks fails to deliver
4. Liver cancer marker could yield blood test for early detection
5. Blood Marker Might Help Spot Early Liver Cancer
6. Natural Protein Could Help Spot, Treat Liver Cancer
7. Diet Change Can Curb Fatty Liver Disease
8. US FDA Fast Tracks PI-88 for the Treatment of Post Resection Liver Cancer
9. The American Liver Foundation Appoints Rick Smith, a Twenty-Year Veteran of The MS Society, as Chief Executive Officer
10. Re-plumbing liver helps beat cancer
11. Free Prescription Drug Program Uses Internet to Deliver Cards - Offers Assistance to Uninsured
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... Viejo, California (PRWEB) , ... June 25, 2016 , ... ... to fit their specific project," said Christina Austin - CEO of Pixel Film Studios. ... fully customizable and all within Final Cut Pro X . Simply select a ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as a method ... —Johnson is one of the first doctors to perform the treatment. Orthobiologics are ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... A recent ... that most people are unfamiliar with. The article goes on to state that individuals ... also many of these less common operations such as calf and cheek reduction. The ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was ... his family verbally and physically. , “When something upset him, he couldn’t control his emotions,” ... He would throw rocks at my other children and say he was going to kill ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. ... accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas of orthodontics, ... and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 ... the "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural ... Structural electronics involves electronic and/or ... protective structures, replacing dumb structures such as vehicle ...
(Date:6/24/2016)... June 24, 2016 Dehaier Medical Systems Ltd. ... which develops, markets and sells medical devices and wearable ... signed a strategic cooperation agreement with Hongyuan Supply Chain ... Chain") on June 20, 2016, to develop Dehaier,s new ... cooperation agreement, Dehaier will leverage Hongyuan Supply Chain,s sales ...
(Date:6/24/2016)... Research and Markets has announced the addition of the ... to their offering. ... World Market for Companion Diagnostics covers the world market for ... report includes the following: , World IVD ... (N. America, EU, ROW), 2015-2020 , World IVD Companion ...
Breaking Medicine Technology: