Navigation Links
Liver Cancer Patients May Get Hope
Date:10/7/2009

Finding could help identify patients who will benefit from interferon therapy, researchers say

WEDNESDAY, Oct. 7 (HealthDay News) -- A short strand of RNA (microRNA) may help doctors identify liver cancer patients who would benefit from treatment with interferon, say U.S. and Chinese researchers.

"Interferon is an experimental therapeutic agent that has been used for many years to treat cancer patients, but with modest benefit," study first author Junfang Ji, of the liver carcinogenesis section at the U.S. National Cancer Institute's Center for Cancer Research, said in a news release.

"Our findings are exciting because we are rediscovering a drug that may have great potential for patients with a particular genomic profile," added senior author Xin Wei Wang, chief of the liver carcinogenesis section. "Being able to treat patients with an existing drug based on a tumor's genomic profile should improve its efficacy and reduce the cost of treatment."

The study of 241 liver cancer patients found that those with low levels of a microRNA called miR-26 lived about four years less than those with higher expression levels of the microRNA.

A separate analysis of liver tumor samples from 135 patients who had had surgery revealed that those with low levels of miR-26 benefitted from receiving adjuvant interferon therapy. Patients who received interferon lived at least 7.7 years longer than those who didn't receive the drug. Interferon didn't benefit patients with normal levels of miR-26.

The findings suggest that checking miR-26 levels in liver tumors may help determine patient prognosis and identify patients who might benefit from interferon treatment in order to prevent disease relapse, the researchers said.

The study appears in the Oct. 8 issue of the New England Journal of Medicine.

More information

The American Cancer Society has more about liver cancer treatment.



-- Robert Preidt



SOURCE: U.S. National Cancer Institute, news release, Oct. 7, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Advanced Age No Bar to Liver Transplant
2. Researchers Find Better Way to Deliver Blood Thinner
3. Federal research plan to determine nanotech risks fails to deliver
4. Liver cancer marker could yield blood test for early detection
5. Blood Marker Might Help Spot Early Liver Cancer
6. Natural Protein Could Help Spot, Treat Liver Cancer
7. Diet Change Can Curb Fatty Liver Disease
8. US FDA Fast Tracks PI-88 for the Treatment of Post Resection Liver Cancer
9. The American Liver Foundation Appoints Rick Smith, a Twenty-Year Veteran of The MS Society, as Chief Executive Officer
10. Re-plumbing liver helps beat cancer
11. Free Prescription Drug Program Uses Internet to Deliver Cards - Offers Assistance to Uninsured
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... WI (PRWEB) , ... October 13, 2017 , ... As ... in medicine known as “patient engagement.” The patient is doing more than filling out ... partners. , “There is an increasing emphasis in health care and research on ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with clinical associate ... primary prevention of cardiovascular diseases during the 15th Annual Women’s Health Conference. ...
(Date:10/13/2017)... ... 13, 2017 , ... Ellevate Network, the leading network for professional women, brought ... gender equality at their inaugural Summit in New York City in June. The event ... audience of over 3 million. To watch the Mobilize Women video, click here ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains ... possible to save lost souls in the Philippines. “The Journey: From the Mountains to ... dedicated teacher of the Bible. She has taught all ages and currently teaches a ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company has ... today’s consumer and regulatory authorities worldwide. From Children’s to Adults 50+, every formula ... the highest standard. , These products are also: Gluten Free, Non-GMO, Vegan, ...
Breaking Medicine News(10 mins):
(Date:10/7/2017)... IRVING, Texas , Oct. 6, 2017   ... industry with more than $100 billion in purchasing power, ... industry news and information. The Newsroom is ... chain and industry trends, infographics, expert bios, news releases, ... Besides having access to a wealth of resources at ...
(Date:10/4/2017)... , Oct. 4, 2017  According to the Centers for Disease Control ... of October . PhysicianOne Urgent Care is helping communities across ... NY , by offering no-cost* flu shots through the end of ... by certain health insurance regulations. ... best time to get a flu shot is by the end of ...
(Date:10/2/2017)... 2, 2017  Eli Lilly and Company (NYSE: ... the third quarter of 2017 on Tuesday, October 24, ... that day with the investment community and media to ... conference call will begin at 9 a.m. Eastern time. ... live webcast of the conference call through a link ...
Breaking Medicine Technology: