Navigation Links
Live-action films of worm sperm help researchers track critical fertility enzymes

SAN FRANCISCO, Nov. 1, 2011 -- Compared to most other cells in an organism, sperm undergo a radical transformation to become compact and mobile delivery systems for paternal DNA. Even though sperm looks and moves quite differently across species, SF State researcher Diana Chu and colleagues now say that there are at least a few key enzymes that are critical for sperm development and mobility in species as different as mice and nematode worms. The study by Chu, et al., was published today online by the journal Genetics.

These enzymes (called PP1 phosphatases) are multitaskers in the nematode, which Chu and the others discovered through unique live-action films of the enzymes at work. First, the enzymes help to separate chromosomes during sperm cell division. After that, they play a role in the development of the sperm's pseudopodsthe appendages that nematode sperm use to move. Pseudopods propel the sperm with a "treadmilling" motion, and the enzymes help disassemble the cell's inner skeleton in a way that pushes the treadmilling forward.

Sperm in mammals like miceand mendon't have pseudopods and don't move in the same way, but they still rely on the phosphatases for development and mobility. Further study of the phosphatases could someday shed light on some of the causes of human infertility, since the enzymes seem to be critical for sperm function.


Contact: Nan Broadbent
San Francisco State University

Page: 1

Related medicine news :

1. UI biologist finds one species of pathogen can produce two distinct biofilms
2. Announces Affordable Dental Plan Sponsorship Video by Sweet Tea Films' Tavin Dillard
3. Researchers find compound effective in destroying antibiotic-resistant biofilms
4. Sperm Moves Best for Moderate Exercisers: Study
5. Healthier Diet, Stronger Sperm?
6. Mouse Sperm Successfully Grown in Lab, Researchers Say
7. Can Crotch Length Predict Sperm Strength?
8. Sperm quality and counts worsening in Finland
9. Biologists discover control center for sperm production
10. Sperm-Producing Cells Coaxed to Produce Insulin
11. Plastics Chemical BPA Tied to Poor Sperm Quality
Post Your Comments:
Related Image:
Live-action films of worm sperm help researchers track critical fertility enzymes
(Date:6/26/2016)... ... , ... On June 10-11, 2016, A Forever Recovery, a holistic treatment center ... Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. This annual ... the world’s leading providers of cereal and other breakfast foods. Its residents often refer ...
(Date:6/25/2016)... ... 2016 , ... Experts from the American Institutes for Research ... June 26-28, 2016, at the Hynes Convention Center in Boston. , AIR experts ... planning, healthcare costs and patient and family engagement. , AIR researchers will be ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe ... from the David Geffen School of Medicine at UCLA. He trained in Internal Medicine ... his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events may ... to unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. To ... for healthy coping following a traumatic event. , Trauma sufferers tend to feel a ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all ... brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... 27, 2016 Jazz Pharmaceuticals plc (Nasdaq: ... the Hart-Scott-Rodino Antitrust Improvements Act of 1976, as amended ... Pharmaceuticals, Inc. ("Celator"; Nasdaq: CPXX ) expired ... Time). As previously announced on May 31, ... merger agreement under which Jazz Pharmaceuticals has commenced a ...
(Date:6/24/2016)... , June 24, 2016  Collagen Matrix, ... design, development and manufacturing of collagen and mineral ... announced today that Bill Messer has ... Marketing to further leverage the growing portfolio of ... devices. Bill joins the Collagen Matrix ...
(Date:6/24/2016)... 24, 2016 Research and ... "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" report ... In-Mold Electronics, Smart Skin, Structural Health Monitoring, ... Structural electronics involves electronic and/or electrical components ... replacing dumb structures such as vehicle bodies or ...
Breaking Medicine Technology: