Navigation Links
Little evidence to support TB interventions in real-world, low-resource settings
Date:12/18/2012

There is little evidence from real world situations in low-and-middle income countries to support the effectiveness and financial value of five interventions* recommended by the World Health Organization (WHO) to control tuberculosis, which may be a reason why these interventions have not been implemented in many countries, according to a study by international experts published in this week's PLOS Medicine.

Over the past few years, WHO has recommended that countries implement several interventions to help control the spread of tuberculosis through measures to improve prevention, diagnosis, and treatment. The authors led by Frank Cobelens from the Amsterdam Institute of Global Health and Development in the Netherlands reviewed 208 appropriate studies to investigate the evidence for the effectiveness of each of these interventions and also for additional information on the setting and conditions of implemented interventions, which might be useful to other countries.

The authors found that there were very few real-world studies reporting on the effectiveness of interventions in program settings (rather than in optimal conditions under research settings). Few studies evaluated the methods used to implement the intervention or addressed delivery and operational issues (such as adherence to treatment) and there were few economic evaluations of the recommended interventions.

The authors say: "There are substantial gaps in published evidence for scale-up for five WHO-recommended TB interventions settings at country level, which for many countries possibly precludes program-wide implementation of these interventions."

They continue: "This lack of ''evidence for scale-up'' may be an important cause of the shortfall in implementation of these interventions in many countries."

The authors add: "There is a strong need for rigorous operational research studies to be carried out in programmatic settings to inform on best of existing and new interventions in TB control."


'/>"/>
Contact: Sumrina Yousufzai
syousufzai@plos.org
415-568-3164
Public Library of Science
Source:Eurekalert

Related medicine news :

1. In children born with severe heart defect, surgical management has little effect on neuro outcomes
2. U.S. Spends Too Little on Public Health Initiatives: Report
3. Botox Offers Little Relief for Migraine, Study Finds
4. A Little More Education, a Little Longer Life?
5. OSHAs Safety Tests Protect Workers at Little Cost: Study
6. Too much vitamin D can be as unhealthy as too little
7. New federal disclosure law may have little impact on drugs prescribed
8. Kids Born Even a Little Early Have Lower School Scores: Study
9. Milk Thistle of Little Help Against Hepatitis C: Study
10. Little evidence supports autism treatment options in adolescents
11. Little Evidence on Value of Treatments for Autism: Report
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... ... December 02, 2016 , ... ... launch of its 60-day free trial program for all of the company’s desktop ... offer a truly hassle free experience. , FlexiSpot’s unique desktop risers use an ...
(Date:12/2/2016)... ... ... The annual time frame to change Medicare health and prescription drug coverage, known ... Medicare beneficiaries who are looking to switch from their current plan to a Medicare ... during this period order for their new policy to go into effect in 2017. ...
(Date:12/2/2016)... ... December 02, 2016 , ... With the number of pain management programs available ... must find the one that works for them. When an inventor from Suisun City, ... worked and decided to share it with others. , He developed a prototype for ...
(Date:12/2/2016)... ... December 02, 2016 , ... Dr. Raffi Hovsepian, a leading ... the 2016 “Guide to America’s Top Plastic Surgeons” for seven consecutive years. The ... education, experience, and professional associations. , One the most frequently honored surgeons ...
(Date:12/2/2016)... ... December 02, 2016 , ... Mediaplanet is proud to announce ... covers the innovative treatments, therapeutic technologies, and revolutionized nutrition that are helping patients ... life 6 years in the last 3 decades,” says Dr. Valentine Fuster, a ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... MONMOUTH JUNCTION, N.J. , Dec. 2, 2016 /PRNewswire/ ... critical care immunotherapy leader commercializing its European Union approved ... in critically-ill and cardiac surgery patients worldwide, announced that ... present at the 9th Annual LD Micro Main ... 8 th , 2016 at the Luxe Sunset Boulevard ...
(Date:12/2/2016)... LYME, Conn. , Dec. 1, 2016  Today, ... has announced the honor of being selected as winners ... include: Simpson Healthcare Executives Website at the PLATINUM level, ... Conversations Training Module at the GOLD Level, and our ... At Simpson Healthcare Executives, we are excited ...
(Date:12/2/2016)... YORK , December 2, 2016 ... of its past losses following Trump,s victory early in ... potential, and fund managers are now predicting an uptick ... at four equities to see how they have fared ... CLDX ), Amicus Therapeutics Inc. (NASDAQ: ...
Breaking Medicine Technology: