Navigation Links
Little evidence to support TB interventions in real-world, low-resource settings
Date:12/18/2012

There is little evidence from real world situations in low-and-middle income countries to support the effectiveness and financial value of five interventions* recommended by the World Health Organization (WHO) to control tuberculosis, which may be a reason why these interventions have not been implemented in many countries, according to a study by international experts published in this week's PLOS Medicine.

Over the past few years, WHO has recommended that countries implement several interventions to help control the spread of tuberculosis through measures to improve prevention, diagnosis, and treatment. The authors led by Frank Cobelens from the Amsterdam Institute of Global Health and Development in the Netherlands reviewed 208 appropriate studies to investigate the evidence for the effectiveness of each of these interventions and also for additional information on the setting and conditions of implemented interventions, which might be useful to other countries.

The authors found that there were very few real-world studies reporting on the effectiveness of interventions in program settings (rather than in optimal conditions under research settings). Few studies evaluated the methods used to implement the intervention or addressed delivery and operational issues (such as adherence to treatment) and there were few economic evaluations of the recommended interventions.

The authors say: "There are substantial gaps in published evidence for scale-up for five WHO-recommended TB interventions settings at country level, which for many countries possibly precludes program-wide implementation of these interventions."

They continue: "This lack of ''evidence for scale-up'' may be an important cause of the shortfall in implementation of these interventions in many countries."

The authors add: "There is a strong need for rigorous operational research studies to be carried out in programmatic settings to inform on best of existing and new interventions in TB control."


'/>"/>
Contact: Sumrina Yousufzai
syousufzai@plos.org
415-568-3164
Public Library of Science
Source:Eurekalert

Related medicine news :

1. In children born with severe heart defect, surgical management has little effect on neuro outcomes
2. U.S. Spends Too Little on Public Health Initiatives: Report
3. Botox Offers Little Relief for Migraine, Study Finds
4. A Little More Education, a Little Longer Life?
5. OSHAs Safety Tests Protect Workers at Little Cost: Study
6. Too much vitamin D can be as unhealthy as too little
7. New federal disclosure law may have little impact on drugs prescribed
8. Kids Born Even a Little Early Have Lower School Scores: Study
9. Milk Thistle of Little Help Against Hepatitis C: Study
10. Little evidence supports autism treatment options in adolescents
11. Little Evidence on Value of Treatments for Autism: Report
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article ... people are unfamiliar with. The article goes on to state that individuals are now ... of these less common operations such as calf and cheek reduction. The Los Angeles ...
(Date:6/24/2016)... ... ... a crisis. Her son James, eight, was out of control. Prone to extreme mood shifts ... upset him, he couldn’t control his emotions,” remembers Marcy. “If there was a knife ... and say he was going to kill them. If we were driving on the ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas ... , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their pencils ... an essay contest in which patients and their families pay tribute to a genetic ... 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® & Innovative ... has initiated cultivation and processing operations at its production facility, and opened its ... Puradigm is the manufacturer of a complete system of proactive air and surface ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016  Arkis BioSciences, a leading ... and more durable cerebrospinal fluid treatments, today announced ... Series-A funding is led by Innova Memphis, followed ... other private investors.  Arkis, new financing will accelerate ... the market release of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... , June 23, 2016  In a startling report released today, ... their residents by lacking a comprehensive, proven plan to eliminate prescription ... definitive ranking of how states are tackling the worst drug crisis ... four states – Kentucky , New ... Vermont . Of the 28 failing states, three – ...
(Date:6/23/2016)... Pa. , June 23, 2016 Bracket ... will launch its next generation clinical outcomes platform, Bracket eCOA ... Meeting held on June 26 – 30, 2016 in ... the first electronic Clinical Outcome Assessment product of its kind ... Booth #715. Bracket eCOA 6.0 is a flexible ...
Breaking Medicine Technology: