Navigation Links
Lithium Beats Valproate for Long-Term Bipolar Therapy
Date:12/23/2009

Combined treatment or monotherapy with lithium helps prevent relapse, study finds

WEDNESDAY, Dec. 23 (HealthDay News) -- People with bipolar I disorder will do best over the long term with lithium treatment alone or a combination of lithium and valproate compared to valproate alone, new research suggests.

Patients who underwent the lithium or lithium/valproate treatments were less likely to relapse regardless of how severe their conditions were at the beginning of treatment, the study authors reported in the Dec. 22 online edition of The Lancet.

But the researchers couldn't say if the combined treatment is better or worse than lithium alone.

People with bipolar disorder have trouble regulating their moods and can swing between highs and lows. In most cases, patients have illness that is chronic or recurs over time. Doctors often prescribe combinations of drugs for these patients after single drugs fail to work, according to background information in a news release about the study.

The new study looked at 330 patients aged 16 and older with bipolar I disorder. The study participants lived in several countries, including the United States, and were randomly assigned to receive lithium, valproate or a combination of both drugs. They were followed for up to two years.

The results show that "for people with bipolar I disorder for whom long-term therapy is clinically indicated, combination therapy with lithium plus valproate is more likely to prevent relapse than is monotherapy with valproate. The 41 percent relative benefit is irrespective of baseline severity of illness, is maintained for up to two years, and is most apparent in prevention of manic relapse," the researchers concluded.

More information

The U.S. National Institute of Mental Health has more on bipolar disorder.



-- Randy Dotinga



SOURCE: The Lancet, news release, Dec. 22, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Possible genetic predictor for response to lithium augmentation in depressed patients
2. Lithium chloride slows onset of skeletal muscle disorder
3. Researchers Test Lithium as Radiation Protector
4. Study: HPV test beats Pap in detecting cervical cancer
5. Ultrasound Beats Blood Test for Gauging Ovarian Cancers: Study
6. Honey Beats Meds at Soothing Kids Cough
7. Arimidex Beats Tamoxifen in Keeping Breast Cancer at Bay
8. Experimental Therapy Beats Back One Patients Melanoma
9. Hanger Orthopedic Group, Inc. Beats First Call Q2 EPS Estimates by $0.05 on 13% Sales Growth and 57.2% Growth in Net Income
10. Colonoscopy Beats Camera Pill at Catching Colon Cancer
11. Newer Drug Beats Tamoxifen for Older Breast Cancer Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... ... , ... Sourced from the Isbre Springs beneath the 5,000 year old Hardanger ... of just 6 ppm TDS (Total Dissolved Solids) in addition to its excellent taste ... several ShopRite and FoodTown stores in NJ and received rave comments from consumers. , ...
(Date:12/2/2016)... ... December 02, 2016 , ... Clarify Health ... has raised $6.0 million in an initial round of funding. The round was ... and their caregivers can receive far better care through the application of the ...
(Date:12/2/2016)... ... ... ‘Tis the season for giving! Today, 20 creative teams across the nation ... the Drug Enforcement Administration as part of the National Red Ribbon Week Photo Contest. ... decorated their campuses with this year’s Red Ribbon Week theme: “YOLO. Be Drug Free,” ...
(Date:11/30/2016)... ... November 30, 2016 , ... Standard ... 75, an annual ranking and recognition of the largest closely held companies headquartered ... ranked from 2008-2016. In addition, Standard Process was awarded the Talent Award for ...
(Date:11/30/2016)... ... 2016 , ... The Cronovo Smartwatch, the first on the ... at an affordable price, is now available on the crowdfunding website Kickstarter ... changer” when it comes to the smartwatch. , "With Cronovo, we’ve combined the ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... -- Boston Scientific Corporation (NYSE: BSX ) ... assets and capabilities of the Neovasc, Inc., (NASDAQ: ... as well as a 15% equity stake in Neovasc, ... Neovasc advanced biological tissue business makes elements used in ... System. * Upon completion of the transaction, the ...
(Date:12/2/2016)... , Dec. 2, 2016 Lianluo ... Smart" or "the Company") which develops, markets and ... in China and international ... Disease Diagnosis and Treatment New Progress Forum, co-hosted ... Guangdong Province , Guangdong Provincial People,s ...
(Date:12/2/2016)... 2016 On Thursday, the NASDAQ Composite ... while the Dow Jones Industrial Average managed to stay in ... markets, which prompted Stock-callers this morning to look at the ... NUVA ), Smith & Nephew PLC (NYSE: ... and Cesca Therapeutics Inc. (NASDAQ: KOOL ). You ...
Breaking Medicine Technology: