Navigation Links
Linking of mutations in 12 genes to ovarian cancer may lead to more effective prevention
Date:10/25/2011

utation. Family history of breast, ovarian, uterine, and pancreatic cancer but not colon cancer were each associated with inherited mutations.

"An observation that has major implications for clinical practice was that nearly one-third of the women with inherited mutations had no prior personal history of breast cancer and no family history of ovarian or breast cancer," Swisher noted. This high proportion of unrecognized risk, she explained, is probably due to the combined effects of small family size, female cancer genes inherited from unaffected fathers, and the simple odds of a mutated gene being inherited or not inherited.

The researcher also found that the age when these types of cancer appear was not generally associated with the likelihood of having an inherited mutation, or with the gene in which a mutation was found.

There were no significant differences in survival rates between women who had one or more of the mutations identified in this study, and women who did not have these particular mutations.

What we found overall, the researchers noted, was that more than one in five cases of ovarian carcinoma were associate with a mutation in tumor suppressor genes. In their normal form, these genes act in a way that keeps tumors from growing.

The findings of this study, the researcher concluded, point to the need to develop comprehensive testing for inherited carcinoma for all women with ovarian, peritoneal or fallopian tube cancer, regardless of their age or family history. The researchers are moving clinical science forward to a time when expensive single gene testing for thousands of dollars will be replaced by testing many genes simultaneously at low cost.


'/>"/>

Contact: Leila Gray
leilag@u.washington.edu
206-685-0381
University of Washington
Source:Eurekalert  

Page: 1 2 3 4

Related medicine news :

1. MSU researcher linking breast cancer patients with alternative therapies
2. San Diego State University and BIOCOM Institute Receive $4.95 Million Grant: The BRIDGE Project, Linking Education to Employment in San Diegos Life Sciences Industry
3. New clues found linking larger animals to colder climates
4. Researchers find further evidence linking Epstein-Barr virus and risk of multiple sclerosis
5. Blinking neurons give thoughts away
6. Experts explore emerging evidence linking diabetes and cancer
7. Investigational eye treatment: Corneal collagen crosslinking research study
8. Doctor Behind Study Linking Vaccine to Autism Accused of Deliberate Fraud
9. Dissecting dyslexia: Linking reading to voice recognition
10. Study linking gut microbe type with diet has implications for fighting GI disorders
11. Linking Pharmacies With Doctors Offices Can Improve Med Adherence: Study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Linking of mutations in 12 genes to ovarian cancer may lead to more effective prevention
(Date:9/21/2014)... UNIWIGS, one of the leading online stores ... pieces, offers a line of human hair lace wigs inspired ... also shows people what the latest celebrity hairstyles ... there are 4 different hairstyles to choose from: a style ... lace wigs and a hot ombre red lace wig. People ...
(Date:9/21/2014)... More than a quarter of house fires are ... of two ways. The first type of dryer fire occurs ... type of dryer fire occurs when lint builds up in the ... due to malfunctioning electrical systems so if it doesn’t appear to ... Here are some ways that you can prevent dryer fires. , ...
(Date:9/21/2014)... (PRWEB) September 21, 2014 Expert witness ... released the findings from its 2014 Expert Witness Fees ... increasingly complex, the demand and compensation for qualified and ... in the Survey’s 16-year history. , The nearly ... hour for their expert work, an increase of 3.2% ...
(Date:9/21/2014)... "I wanted to be able to ... sugary, foul-tasting energy drinks," said an inventor from Fresh ... to drink plain, old coffee. That is why I ... developed ENERG CHEWING GUM to provide a healthy energy ... formula contains nutritious vitamins, minerals and antioxidants. It also ...
(Date:9/21/2014)... "I want to help people who are having ... money for chiropractors," said an inventor from St. Amat, ... for myself." , The Stretch is a device that ... and align the spine properly. It improves flexibility and ... nerves. Compact and easy to use, it's ideal for ...
Breaking Medicine News(10 mins):Health News:UniWigs New Arrivals Just In- Human Hair Lace Wigs Inspired By Famous Celebrities 2Health News:Restoration Local Offers Tips to Avoid Dryer Fires 2Health News:Restoration Local Offers Tips to Avoid Dryer Fires 3Health News:ExpertPages 2014 Survey Reports Expert Witness Hourly Fees Record All-Time Highs as Demand for Qualified Experts Continues to Grow 2
... of deadly neuroectodermal tumors , MONDAY, Dec. 7 (HealthDay ... role in a particularly aggressive type of childhood brain ... tumors (CNS-PNETs), the discovery of these oncogenes may lead ... , "Lack of insight into the molecular pathogenesis of ...
... , , SAN FRANCISCO, Dec. 7 Senior advocacy organizations ... grant from Verizon on Tuesday (Dec. 8) to continue the Commitment to End Abuse ... Hank Lacayo, president and CEO, Congress of California Seniors, ... and CEO, Self-Help for the Elderly, ...
... , GREENDALE, Wis., Dec. 7 Taste of Home ... Comfort Food Diet Cookbook, featuring America,s favorite comfort recipes with ... Food Diet Cookbook , on shelves December 31, 2009, is a ... pounds without feeling deprived. Enjoy pizza, lasagna, mac-n-cheese, pulled pork and ...
... ― The second-generation proteasome inhibitor carfilzomib is showing noteworthy ... among multiple myeloma patients in a phase II clinical ... of the American Society of Hematology. The updated ... relapsed or resistant multiple myeloma who have received one ...
... ... dental emergency, finding a qualified, experienced dentist is a crucial step in preserving your smile ... Minneapolis, ... stand against the high prices and inconvenience of emergency dental procedures. Whether a tooth is ...
... fewer hassles, study finds , MONDAY, Dec. 7 (HealthDay News) ... just as effective in preventing dangerous venous clots as an ... to manage, a new study finds. , Dabigatran is marketed ... not yet approved for use in the United States. , ...
Cached Medicine News:Health News:New Target May Be Eyed in Kids' Brain Cancer 2Health News:The Country's Largest Cooking Magazine Announces The Comfort Food Diet Cookbook 2Health News:The Country's Largest Cooking Magazine Announces The Comfort Food Diet Cookbook 3Health News:Drug shows positive responses, low side-effects in multiple myeloma 2Health News:Minneapolis Dentists, Shamblott Family Dentistry, Ease the Pain and Cost of Emergency Dental Procedures 2Health News:New Blood Thinner Could Replace Warfarin to Fight Venous Clots 2Health News:New Blood Thinner Could Replace Warfarin to Fight Venous Clots 3
(Date:9/19/2014)... , Sept. 19, 2014 The American Association ... Medical Design and Manufacturing has joined the AAHomecare Corporate ... Harvey Diamond have been actively involved in ... as it has quickly grown into a major global ... like Drive allows AAHomecare to increase efforts on behalf ...
(Date:9/19/2014)... -- According to market research report, ... & Laboratory), Industry (Food, Pharmaceutical, Biotechnology, Surgical Procedure, ... Geography - Global Trends & Forecast to 2019", ... market on the basis of various types, applications, ... market size of each of these segments in ...
(Date:9/19/2014)... and ORLANDO, Fla. , ... supporting Inspire therapy continues to grow, with the publication ... published on-line in Otolaryngology – Head and ... causes a worsening of both objective and subjective measures ... directly attribute Inspire therapy for the reduction in obstructive ...
Breaking Medicine Technology:Drive Medical Design & Manufacturing Joins AAHomecare Corporate Partner Program 2Lyophilization Market Worth $5,121.5 Million by 2019 2Lyophilization Market Worth $5,121.5 Million by 2019 3New Data shows Reductions in obstructive sleep apnea (OSA) severity and improvement of quality of life with Inspire therapy 2New Data shows Reductions in obstructive sleep apnea (OSA) severity and improvement of quality of life with Inspire therapy 3New Data shows Reductions in obstructive sleep apnea (OSA) severity and improvement of quality of life with Inspire therapy 4
7mm Cross Hairs; Available in 4.5mm to 7.0mm in 0.5mm increments; Ring depth available from 2 to 4mm in 0.5mm increments.; in stainless steel....
2.0mm Rounded Tip, 12mm From Tip to Bend Gently Curved, 15mm Shaft; In Titanium...
Double ended with 0.5mm x 10mm and 1.0mm x 15mm blades; both blades gently curved; round serrated handle, In Titanium....
0.6mm Tip x10mm Shaft, Straight Shaft, 90 Degree Hook at Tip; overall length 120mm; in Titianium....
Medicine Products: