Navigation Links
Link shown between Crohn's disease and virus
Date:6/27/2013

atrician Niklas Nystrm, the pathologist Alkwin Wanders, virus researchers Gun Frisk and Oskar Skog, the molecular biologist Mats Nilsson, and the geneticist Ulf Gyllensten at Uppsala University and Uppsala University Hospital, along with cell biologists Jonas Fuxe and Tove Berg the paediatrician Yigael Finkel at Karolinska Institutet in Stockholm.

This unique composition, with complementary clinical and scientific expertise, has been extremely fruitful for our studies, says Alkwin Wanders.

In the present study the researchers investigated whether the RNA virus were present in children with Crohns disease. They focused in particular on the prevalence of enteroviruses, a group of RNA viruses that are known to infect the intestinal mucous lining.

The results showed significant amounts of enteroviruses in the intestines of all of the children with Crohns disease, whereas the control group had no or only minimal amounts of enteroviruses in their intestines. Similar results were obtained using two different methods. Enteroviruses were found not only in intestinal mucous linings but also in so-called nerve cell ganglia in deeper segments of the intestinal wall. Receptors for a group of enteroviruses were also found in both the intestinal mucous linings and nerve cell ganglia, which may explain how the virus can make its way into the nerve system in the intestine.

Another interesting finding is that the enterovirus could be thought to be stored in nerve cells in the intestine and to spread to different parts of the intestine via nerve fibres. This would explain both the fact that the disease is periodic (comes and goes) and the fact that it often affects multiple segments of the intestines, says Alkwin Wanders.

The present study comprises nine children with advanced Crohn's disease and fifteen children with incipient Crohn's disease symptoms. The research now wants to go on to examine larger groups of patients and more control
'/>"/>

Contact: Alkwin Wanders
alkwin.wanders@igp.uu.se
46-076-226-9430
Uppsala University
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Announces New hCG Diet Plans to Promote Fast Weight Loss Shown to Reduce the Risk & Symptoms of Chronic Fatigue
2. Massage therapy shown to improve stress response in preterm infants
3. Positive social support at work shown to reduce risk of diabetes
4. Dedicated cleaning staff shown to reduce C. difficile contamination in hospital rooms
5. First single gene mutation shown to result in type 1 diabetes
6. Contact precautions shown to modify healthcare workers care delivery
7. Topical simvastatin shown to accelerate wound healing in diabetes
8. BPA shown to disrupt thyroid function in pregnant animals and offspring
9. Harmless condition shown to alter brain function in elderly
10. Drug shown to improve memory in those with Down syndrome
11. Specialized MRI scans assess value of anti-cancer chemotherapy long before tumors shown to shrink
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2015)... , ... July 30, 2015 , ... ... at multinational organizations and NGO’s, according to a new survey by leading international ... that property damage and employee medical expenses represented the largest sources of financial ...
(Date:7/30/2015)... ... July 30, 2015 , ... After a three year trial designed to ... commonly known as the “bionic eye,” researchers have determined the trial to be a ... patients facing or already affected by complete vision loss as a result of Retinitis ...
(Date:7/30/2015)... ... July 30, 2015 , ... According to Chicago ... find a complete removable denture acceptable. The demand for dental implants is rising ... less expensive, immediate loading techniques will have the ability to offer the patient ...
(Date:7/30/2015)... ... 2015 , ... When trying to gain weight, many people place a lot of focus on the different types ... to be consumed. However, another key component to successful weight gain is knowing when ... this, CB-1 Weight Gainer gives three tips on when to eat to gain weight. ...
(Date:7/30/2015)... ... ... PeopleKeys, a company with over 30 years of experience in behavioral analysis, ... the newest installment in their popular DISC for the Real World series, will air ... webinar is intended for people interested in training others to use DISC behavioral analysis ...
Breaking Medicine News(10 mins):Health News:New Clements Worldwide Global Risk Survey Shows Political Risk and Instability Top Managers' Concerns 2Health News:New Clements Worldwide Global Risk Survey Shows Political Risk and Instability Top Managers' Concerns 3Health News:The Vision Enhancing “Bionic Eye” Deemed Safe For Long Term Use After Three Year Clinical Trial 2Health News:Chicago Implant Dentist/Implantologist Dr. Irfan Atcha Speaks to Local Dentists about Advances in Dental Implants in August. 2Health News:Chicago Implant Dentist/Implantologist Dr. Irfan Atcha Speaks to Local Dentists about Advances in Dental Implants in August. 3Health News:CB-1 Weight Gainer Gives Three Tips on When to Eat to Gain Weight 2Health News:CB-1 Weight Gainer Gives Three Tips on When to Eat to Gain Weight 3Health News:PeopleKeys to Air “Managing Stress: Train the Trainer” DISC Webinar 2
... WASHINGTON, April 8, 2008 The following is a,statement ... Governor Ted Strickland and Ohio legislators have abandoned ... their underhanded actions today to,raid funds from the Ohio ... to come more Ohio children will become addicted to,tobacco, ...
... Important to Protect Animal, Human Health, WASHINGTON, ... today launched its newly designed "Keeping Animals Healthy",website ... important,role of public policy in providing animal medicines ... are becoming more aware of the relationship between ...
... Filed in ... ... KV Pharmaceutical,Company (NYSE: KVa/KVb), a fully integrated specialty pharmaceutical,company that ... pharmaceutical,products, announced today that it has reached a comprehensive settlement,agreement ...
... Clinical Trial Results on Preoperative Chemotherapy in Early Breast ... no better than six cycles in women with early ... according to data from a randomized controlled trial. Additionally, ... cycles of one drug combination did not benefit from ...
... of the main obstacles towards progress in the developing ... that have not been seriously addressed by the public ... new book, Forgotten People, Forgotten Diseases, published by ASM ... the world have too long been ignored. Parasitic ...
... Ultravist(R) are part of Amerinet,s Portfolio of ... Contracted ... HealthCare,Pharmaceuticals Inc., a leader in diagnostic imaging, announced today that,the ... to make,Magnevist(R) (gadopentetate dimeglumine) injection and Ultravist(R),(iopromide) injection available to ...
Cached Medicine News:Health News:KV Pharmaceutical Company Announces Proposed Settlement in Principle of Derivative Shareholder Litigation 2Health News:KV Pharmaceutical Company Announces Proposed Settlement in Principle of Derivative Shareholder Litigation 3Health News:Other highlights in the April 8 JNCI 2Health News:Other highlights in the April 8 JNCI 3Health News:Other highlights in the April 8 JNCI 4Health News:Forgotten diseases key to lifting developing world from poverty, destitution and despair 2Health News:Bayer HealthCare Pharmaceuticals, Amerinet Extend Contrast Media Agreement 2Health News:Bayer HealthCare Pharmaceuticals, Amerinet Extend Contrast Media Agreement 3Health News:Bayer HealthCare Pharmaceuticals, Amerinet Extend Contrast Media Agreement 4
(Date:7/29/2015)... Alvarado Hospital unveiled its new facility ... & Joint Institute. The institute is entirely devoted ... surgery and joint replacement. The Spine & Joint ... experience-focused approach. For example, patients are encouraged to ... than patient gowns. "From the ...
(Date:7/29/2015)... LAKE FOREST, Calif. , July 29, ... ) ("Cryoport" or the "Company"), the leading ... the life sciences industry, serving markets including ... organizations, vaccine manufacturers, animal health, and reproductive ... completed the sale of common stock and warrants ...
(Date:7/29/2015)...  Ortho-Clinical Diagnostics, Inc. (OCD) today announced the presentation ... address a range of important tests for clinical labs ... The scientific posters will be delivered during the 2015 ... held July 26 - 30 in Atlanta, ... is emerging stronger than ever since becoming a stand-alone ...
Breaking Medicine Technology:The Alvarado Spine & Joint Institute Opens July 30 in San Diego 2Cryoport Completes $6.8 Million Equity Capital Raise 2Cryoport Completes $6.8 Million Equity Capital Raise 3Ortho-Clinical Diagnostics, Inc. Presents Data On Five Assays In Development At American Association For Clinical Chemistry Annual Meeting 2Ortho-Clinical Diagnostics, Inc. Presents Data On Five Assays In Development At American Association For Clinical Chemistry Annual Meeting 3
... DIEGO, Feb. 11, 2011 Conatus Pharmaceuticals Inc. today ... Preferred Stock private placement financing.  This financing was led ... and included participation by existing investors; Aberdare Ventures, Advent ... Roche Venture Fund.  Conatus will use the proceeds to ...
... LOS ANGELES, Feb. 11, 2011 Nationally-acclaimed researcher and ... speech at the 11th National Conference on Cancer Nursing ... potentially deadly infections they were supposed to prevent. ... needleless IV connector devices with silver coated or silver ...
Cached Medicine Technology:Conatus Pharmaceuticals Completes $20 Million Series B Private Placement Financing 2Instead of Preventing Infections, Silver Coated Needleless IV Connectors May Actually Cause Them, a Nationally-Recognized Expert Tells National Conference on Cancer Nursing Research 2
... The new Primus PDQ Plus for the determination ... and accurate results. The PDQ Plus is a ... on-line barcode reading for the ultimate in safety ... affinity which is well known to be interference-free ...
Micromat II Hemoglobin A1c instrument is an easy-to-use, accurate and precise instrument with an requirement of only 10 L of capillary or venous sample....
... Cascade M-4 is a manual hemostasis ... routine clotting assays - PTs, aPTTs, ... for easy, inexpensive, low-volume testing, this ... big on features, offering time and ...
... a fully automated, benchtop coagulation workstation ... immunological assays in true random access ... sample management offers high throughput and ... the need to interrupt current testing. ...
Medicine Products: