Navigation Links
Link between widely used osteoporosis drugs and heart problems probed
Date:4/6/2009

WINSTON-SALEM, N.C. New research at Wake Forest University School of Medicine evaluated the link between a common class of drugs used to prevent bone fractures in osteoporosis patients and the development of irregular heartbeat.

The study's findings appear in the current issue of Drug Safety, a publication of the International Society of Pharmacovigilance covering the safe and proper use of medicines.

"Some trials show there could be a potential link between the use of bisphosphonates and the development of serious heart rhythm problems, but in our study the link wasn't conclusive," said Sonal Singh, M.D., M.P.H., an assistant professor of internal medicine and lead investigator for the study. "So we urge that additional investigations be conducted."

Bisphosphonates, found in prescription drugs including BonivaTM, FosomaxTM, ReclastTM and ActonelTM, inhibit the breakdown of bones, which reduces the risk of fractures, especially those of the spine and hips in older patients. The first such drugs were approved for use in the mid-1990s.

Early studies indicated that the use of bisphosphonates might cause problems with heart rhythm, or atrial fibrillation, which increases the risk for stroke or heart attack. For the study published this month, researchers analyzed the data from previous observational studies and clinical trials to determine the link between bisphosphonate therapy and irregular heart beat.

Researchers found that bisphosphonate use was associated with a significant increase in the incidence of "serious" heart rhythm disturbances, classified by hospitalization, disability or death resulting from the condition. However, when they included "non-serious" cases in their analysis, they found no overall increased risk of atrial fibrillation, the study shows.

"Our findings were discordant, with conflicting results," Singh said. "The challenge now is to figure out what it all means."

'/>"/>
Contact: Jessica Guenzel
jguenzel@wfubmc.edu
336-716-3487
Wake Forest University Baptist Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Comparison of obstetric outcomes between on-call and patients own obstetricians
2. Mailman School of Public Health study examines link between racial discrimination and substance use
3. New link between estrogen and breast cancer
4. Link Uncovered Between Benign Prostatic Hyperplasia and NSAIDs, Says Harvard Mens Health Watch
5. Link Between Chronic Pain and Insomnia Uncovered at PAINWeek 2007
6. Scientists demonstate link between genetic variant and effectiveness of smoking cessation meds
7. Researchers discover correlation between GERD and obesity in females
8. NIH awards $10.8M to Columbia to study connection between diabetes and heart disease
9. Researchers Pinpoint Link Between Caloric Restriction and Longevity
10. Link Between Air Pollution, Stroke Gets Clearer
11. No Link Between Anti-Nausea Drug, Heart Trouble
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/23/2014)... November 23, 2014 AngelWeddingDress.com ... a new selection of beach wedding dresses. “If you ... prices, visit AngelWeddingDress.com as soon as possible. Here you ... The sales manager says. , Holding a big marriage ... And choosing a beautiful beach wedding dress is uppermost ...
(Date:11/23/2014)... Wright & Schulte LLC recently filed ... West Virginia residents who allege that they developed thyroid ... to drinking C8 contaminated water released by the ... to the C8 complaints, the plaintiffs were exposed to ... in at least one of the six water districts ...
(Date:11/22/2014)... (PRWEB) November 23, 2014 Cancer researchers ... a connection between intercellular communication tunnels and the growth ... the full story on the Surviving Mesothelioma website. ... and the University of Minnesota have just released their ... information and materials between cells. They found that ...
(Date:11/22/2014)... BambooFlooringChina.com is a famous brand in the bamboo flooring ... of bamboo mats ; the new models are offered ... , According to the sales manager of BambooFlooringChina.com, Bamboo is ... renewable resource. Their bamboo mats are 100% made from natural ... natural bamboo with caramel bamboo strips. , “Bamboo ...
(Date:11/22/2014)... November 22, 2014 In order to provide ... promotion of cocktail party dresses. The business knows that a ... social occasions. , Now, the party dresses supplier’s ... 70% off. As the leading company in fashion industry, LunaDress ... outfit for every customer. So it always raises the professional ...
Breaking Medicine News(10 mins):Health News:Beach Wedding Dresses Added to Outstanding Online Dress Company AngelWeddingDress.com 2Health News:40 C8 Lawsuit Claims Filed By Wright & Schulte LLC Alleged Serious Illness Due To C8 Contaminated Water In Ohio And West Virginia 2Health News:40 C8 Lawsuit Claims Filed By Wright & Schulte LLC Alleged Serious Illness Due To C8 Contaminated Water In Ohio And West Virginia 3Health News:40 C8 Lawsuit Claims Filed By Wright & Schulte LLC Alleged Serious Illness Due To C8 Contaminated Water In Ohio And West Virginia 4Health News:Study Links Cellular ‘Tunnels’ to Mesothelioma Proliferation, According to Surviving Mesothelioma 2Health News:Trendy Bamboo Mats Online Now By BambooFlooringChina.com 2Health News:LunaDress Unveils Fabulous Cocktail Party Dresses 2
... demonstrated that a protein called NEDD9 may be required for ... grow. Their findings, based on the study of a mouse ... of Cancer Research , available on-line now. "For ... that directly demonstrates reduced levels of NEDD9 in a living ...
... shows no signs of slowing, researchers say , ... trends continue, more than half of babies born in rich ... and they,ll have less disability than elderly people in previous ... increases in life expectancy evident in rich nations since 1840 ...
... Oct. 2 As part of a continuing effort ... in their areas, the online consumer advocacy resource Plastic ... three esteemed Baltimore plastic surgeons to its national network ... Lawrence Rosenberg and Dr. Daniel P. Markmann are experienced, ...
... DuBose, of DuBose Law Firm, PLLC, has been recognized by Law ... the select "Texas Super Lawyers" in the October, 2009 Texas Monthly ... as one of the "Best Lawyers in Dallas" by D Magazine. ... and Texas Monthly magazine as a "Rising Star of ...
... Oct. 2 More and more people are driven beyond ... by their desire to achieve success and happiness, they become ... their family. They strive for contentment, but find themselves exhausted ... to understand what it takes to truly make them happy. ...
... ... and Mount Airy Church of God in Christ for A Day of Breast Health Awareness, ... Philadelphia, ... care organization in Pennsylvania, in conjunction with Praise is The Cure and the Health Ministry ...
Cached Medicine News:Health News:NEDD9 protein supports growth of aggressive breast cancer 2Health News:Half of U.S. Babies Living Today May Reach 100 2Health News:Half of U.S. Babies Living Today May Reach 100 3Health News:Leading Baltimore Plastic Surgeons Join Plastic Surgery Portal Network 2Health News:'Texas Monthly' Recognizes Ben DuBose Among the Super Lawyers of Texas 2Health News:Holistic Success - How To Achieve Health, Happiness and Genuine Success: A Web-TV Premiere 2Health News:More than 500 Breast Cancer Survivors and Community Supporters to Attend Annual 'Praise is The Cure' Event 2
(Date:11/21/2014)... 20, 2014 /PRNewswire/-- CANTEL MEDICAL CORP. (NYSE: CMN ) ... Officer, will be presenting at the 26 th Annual ... in New York . The formal presentation ... ET. In addition, Mr. Krakauer and Jorgen B. Hansen ... meetings during the day. An audio webcast ...
(Date:11/21/2014)... QC , Nov. 20, 2014 /CNW Telbec/ - ... to announce the following appointments: ... team in the newly created role of Chief Commercial ... BioPhotonic system using topical photoconverter gel for the treatment ... surgical and traumatic wounds, recently approved in ...
(Date:11/21/2014)... Texas , 21. November 2014 ... was sich am Morgen des 14. Februar 2014 zugetragen ... jedoch wohl kaum vergessen. Video - ... dass ich dabei war, mein morgendliches Training zu machen", ... waren zu der Zeit begeisterte Anhänger der ...
Breaking Medicine Technology:KLOX Technologies announces executive appointments 2KLOX Technologies announces executive appointments 3KLOX Technologies announces executive appointments 4Tochter rettet Vater durch Herz-Lungen-Wiederbelebung vor plötzlichem Herztod 2Tochter rettet Vater durch Herz-Lungen-Wiederbelebung vor plötzlichem Herztod 3
... China , April 22 /PRNewswire-Asia-FirstCall/ -- ... "the Company"),a Xianyang-based manufacturer of a leading over-the-counter ... Aoxing"), and a variety of,pharmaceutical products, today announced ... its common stock on the NASDAQ Global Market. ...
... Boehringer Ingelheim Pharmaceuticals, Inc. and Connecticut United for Research Excellence, ... a comprehensive initiative designed to bring hands-on science education directly to ... , , , ... of the effort is the Boehringer Ingelheim Science Quest mobile laboratory ...
Cached Medicine Technology:Biostar Pharmaceuticals Approved for Listing on NASDAQ Global Market 2Biostar Pharmaceuticals Approved for Listing on NASDAQ Global Market 3Biostar Pharmaceuticals Approved for Listing on NASDAQ Global Market 4New Boehringer Ingelheim Science Quest Mobile Laboratory Brings Hands-On Science Education to Priority Connecticut Elementary Schools 2New Boehringer Ingelheim Science Quest Mobile Laboratory Brings Hands-On Science Education to Priority Connecticut Elementary Schools 3New Boehringer Ingelheim Science Quest Mobile Laboratory Brings Hands-On Science Education to Priority Connecticut Elementary Schools 4New Boehringer Ingelheim Science Quest Mobile Laboratory Brings Hands-On Science Education to Priority Connecticut Elementary Schools 5
Smooth colibri tip; In Titanium....
Straight Shafts with 0.2mm 1X2 Teeth, 5mm Tying Platform; In Titanium....
Gently curved 5mm Platform With 12, 0.12mm Teeth; In Titanium....
Curved Shaft with 5mm Platform; 1x2, 0.12 mm teeth; In Titanium....
Medicine Products: