Navigation Links
Limiting polyunsaturated fatty acid levels in pregnancy may influence body fat of children

Southampton researchers have demonstrated that mothers who have higher levels of n-6 polyunsaturated fatty acids (PUFAs), which are found in cooking oils and nuts, during pregnancy have fatter children.

The study, carried out by the Medical Research Council (MRC) Lifecourse Epidemiology Unit, University of Southampton, assessed the fat and muscle mass of 293 boys and girls at four and six years, who are part of the Southampton Women's Survey (SWS), a large prospective mother-offspring cohort.

Their assessments were compared to the concentrations of PUFAs which were measured in blood samples collected from their mothers during pregnancy.

The study, published in the January edition of Journal of Clinical Endocrinology and Metabolism, found that children who were born to mothers who had had greater levels of n-6 PUFAs during pregnancy had greater fat mass.

Dr Nicholas Harvey, Senior Lecturer at the MRC Lifecourse Epidemiology Unit, University of Southampton, who led the research with Dr Rebecca Moon, Clinical Research Fellow, comments: "Obesity is a rising problem in this country and there have been very few studies of mother's fatty acid levels during pregnancy and offspring fat mass. These results suggest that alterations to maternal diet during pregnancy to reduce n-6 PUFAs intake might have a beneficial effect on the body composition of the developing child."

Results from the study also showed weaker associations between a mother's levels of n-3 PUFAs, more commonly known as omega 3 and found in fish oil, and muscle mass in their offspring the higher the level of n-3 the less fat and more muscle and bone in the baby.

This could suggest that a pregnancy supplementation strategy would be beneficial. However Dr Moon says: "n-6 and n-3 PUFAs seem to act in opposite directions on fat mass; previous trials have attempted to use n-3 supplementation to reduce fat mass, but our results suggest that such an approach might work best when combined with a reduction in dietary n-6 intake."

Professor Cyrus Cooper, Professor of Rheumatology and Director of the MRC Lifecourse Epidemiology Unit, University of Southampton adds: "This study forms part of a larger programme of research at the MRC Lifecourse Epidemiology Unit and University of Southampton in which we are seeking to understand how factors such as diet and lifestyle in the mother during pregnancy, and of the child in early life, influence a child's body composition and bone development. This work should help us to design interventions aimed at optimising body composition in childhood and later adulthood and thus improve the health of future generations."


Contact: Becky Attwood
University of Southampton

Related medicine news :

1. New Guidelines Urge Limiting Endoscopy for GERD
2. Limiting neurosurgery residents work hours hasnt decreased complication rates
3. Scripps Florida scientists develop new compound that reverses fatty liver disease
4. Analysis of conflicting fish oil studies finds that omega-3 fatty acids still matter
5. Girls with eating disorders regain healthy fatty acid levels when their weight normalizes
6. Pictures of Fatty, Sugary Foods May Spur Cravings
7. Fatty acid found in fish prevents age-related vision loss: U of A medical research
8. US Drug Watchdog Now Urges DePuy Pinnacle Metal Hip Recipients To Get A Blood Test and to Call Them For The Names Of The Best Lawyers If Their Metals Levels Are Elevated
9. High BPA Levels in Kids Linked to Risk for Heart, Kidney Damage: Study
10. US Drug Watchdog Now Urges All US Recipients of an All Metal Hip Implant to Get a Blood Test for Cobalt-Chromium Levels and They Offer Victims of a Failure Legal Contacts
11. Higher levels of obesity associated with increased risk of death
Post Your Comments:
(Date:11/30/2015)... ... November 30, 2015 , ... Brenntag Specialties, Inc. (BSI) ... for the Nutraceutical Specialties products into oral solid dosage in the over the ... “We are pleased to announce our expanded distribution agreement with ASI.” said Steve ...
(Date:11/30/2015)... ... November 30, 2015 , ... An inventor from Charlottesville, Va., is ... "My last baby had high blood pressure due to loud noises," she said, "so ... babies from noise pollution as well as radio waves and microwaves." , The baby ...
(Date:11/30/2015)... ... November 30, 2015 , ... Since its ... specializing in independent living, assisted living and all other retirement options. Support for ... awareness and research remains a top priority. , So it’s no surprise ...
(Date:11/30/2015)... New York, New York (PRWEB) , ... November 30, 2015 , ... ... at the Greater New York Dental Meeting. Their Ecosystem empowers dentists to make complex ... Dentists who visit the booth will receive a free fee survey with 10 procedures ...
(Date:11/30/2015)... ... November 30, 2015 , ... ... of DataTrade Solutions Inc., a Healthcare IT consulting, development and support company. The ... and technical experience available within DataTrade to extend the services currently provided by ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... , Nov. 30, 2015   Nuance Communications, Inc. ... National Decision Support Company (NDSC) today jointly announced ... collaboration capabilities that utilize the American College of Radiology,s ... provider organizations to comply with current and emerging ... --> By combining clinical decision support, ...
(Date:11/30/2015)... , Nov. 30, 2015  Novartis will demonstrate the ... 57 th American Society of Hematology (ASH) Annual ... myelomas as well as supportive care, including key findings ... personalized cell therapies. The ASH Annual Meeting will be ... . Novartis Oncology . "We will be ...
(Date:11/30/2015)... Israel , Nov. 30, 2015  OticPharma, Ltd., ... and developing innovative therapies for ear, nose, and throat ... A. Katkin as chairman of the company,s board ... executive officer for OticPharma, Ltd.  "Keith brings a wealth ... will be able to share this experience and provide ...
Breaking Medicine Technology: