Navigation Links
Limiting polyunsaturated fatty acid levels in pregnancy may influence body fat of children

Southampton researchers have demonstrated that mothers who have higher levels of n-6 polyunsaturated fatty acids (PUFAs), which are found in cooking oils and nuts, during pregnancy have fatter children.

The study, carried out by the Medical Research Council (MRC) Lifecourse Epidemiology Unit, University of Southampton, assessed the fat and muscle mass of 293 boys and girls at four and six years, who are part of the Southampton Women's Survey (SWS), a large prospective mother-offspring cohort.

Their assessments were compared to the concentrations of PUFAs which were measured in blood samples collected from their mothers during pregnancy.

The study, published in the January edition of Journal of Clinical Endocrinology and Metabolism, found that children who were born to mothers who had had greater levels of n-6 PUFAs during pregnancy had greater fat mass.

Dr Nicholas Harvey, Senior Lecturer at the MRC Lifecourse Epidemiology Unit, University of Southampton, who led the research with Dr Rebecca Moon, Clinical Research Fellow, comments: "Obesity is a rising problem in this country and there have been very few studies of mother's fatty acid levels during pregnancy and offspring fat mass. These results suggest that alterations to maternal diet during pregnancy to reduce n-6 PUFAs intake might have a beneficial effect on the body composition of the developing child."

Results from the study also showed weaker associations between a mother's levels of n-3 PUFAs, more commonly known as omega 3 and found in fish oil, and muscle mass in their offspring the higher the level of n-3 the less fat and more muscle and bone in the baby.

This could suggest that a pregnancy supplementation strategy would be beneficial. However Dr Moon says: "n-6 and n-3 PUFAs seem to act in opposite directions on fat mass; previous trials have attempted to use n-3 supplementation to reduce fat mass, but our results suggest that such an approach might work best when combined with a reduction in dietary n-6 intake."

Professor Cyrus Cooper, Professor of Rheumatology and Director of the MRC Lifecourse Epidemiology Unit, University of Southampton adds: "This study forms part of a larger programme of research at the MRC Lifecourse Epidemiology Unit and University of Southampton in which we are seeking to understand how factors such as diet and lifestyle in the mother during pregnancy, and of the child in early life, influence a child's body composition and bone development. This work should help us to design interventions aimed at optimising body composition in childhood and later adulthood and thus improve the health of future generations."


Contact: Becky Attwood
University of Southampton

Related medicine news :

1. New Guidelines Urge Limiting Endoscopy for GERD
2. Limiting neurosurgery residents work hours hasnt decreased complication rates
3. Scripps Florida scientists develop new compound that reverses fatty liver disease
4. Analysis of conflicting fish oil studies finds that omega-3 fatty acids still matter
5. Girls with eating disorders regain healthy fatty acid levels when their weight normalizes
6. Pictures of Fatty, Sugary Foods May Spur Cravings
7. Fatty acid found in fish prevents age-related vision loss: U of A medical research
8. US Drug Watchdog Now Urges DePuy Pinnacle Metal Hip Recipients To Get A Blood Test and to Call Them For The Names Of The Best Lawyers If Their Metals Levels Are Elevated
9. High BPA Levels in Kids Linked to Risk for Heart, Kidney Damage: Study
10. US Drug Watchdog Now Urges All US Recipients of an All Metal Hip Implant to Get a Blood Test for Cobalt-Chromium Levels and They Offer Victims of a Failure Legal Contacts
11. Higher levels of obesity associated with increased risk of death
Post Your Comments:
(Date:11/27/2015)... ... ... According to an article published November 13th on, much ... revolved around the fact that proper dental care, both at-home and in the dental ... periodontal disease (more commonly referred to as gum disease) and diabetes. According to Dr. ...
(Date:11/27/2015)... ... November 27, 2015 , ... The rapid speed at ... people age, more care is needed, especially with Alzheimer’s, dementia and other cognitive ... being overworked. The forgotten part of this equation: 80 percent of medical care ...
(Date:11/27/2015)... PA (PRWEB) , ... November 27, 2015 , ... ... how filthy the toilets were," said an inventor from Hillside, N.J. "Many people ... improved seat cover so that individuals will always be protected from germs." , ...
(Date:11/27/2015)... ... November 27, 2015 , ... ProSidebar: Fashion ... Cut Pro X. With ProSidebar: Fasion, video editors can easily add an informative ... a minimalist title opener. Utilize presets featuring self-animating drop zones, lines, bars, and ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... ... of the well-respected Microsoft Dynamics SL User Group (MSDSLUG). Recognized as Microsoft’s official ... independent group of Microsoft Dynamics SL software users, partners, industry experts and representatives. ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... , November 26, 2015 /PRNewswire/ ... announced the addition of the  "2016 ... the Global Cell Surface Testing Market: ... report to their offering.  --> ... addition of the  "2016 Future Horizons ...
(Date:11/26/2015)... Research and Markets ( ) has ... Market by Type (Dressings, Therapy Devices, Active Wound Care), ... Facility), and Geography - Global Forecast to 2020" ... --> The purpose of this report ... the global advanced wound care market. It involves deep ...
(Date:11/26/2015)... 26, 2015 ) ... Administration of High Viscosity Drugs" report to ... announced the addition of the "Self Administration ... offering. --> Research and Markets ( ... "Self Administration of High Viscosity Drugs" ...
Breaking Medicine Technology: