Navigation Links
Limiting polyunsaturated fatty acid levels in pregnancy may influence body fat of children

Southampton researchers have demonstrated that mothers who have higher levels of n-6 polyunsaturated fatty acids (PUFAs), which are found in cooking oils and nuts, during pregnancy have fatter children.

The study, carried out by the Medical Research Council (MRC) Lifecourse Epidemiology Unit, University of Southampton, assessed the fat and muscle mass of 293 boys and girls at four and six years, who are part of the Southampton Women's Survey (SWS), a large prospective mother-offspring cohort.

Their assessments were compared to the concentrations of PUFAs which were measured in blood samples collected from their mothers during pregnancy.

The study, published in the January edition of Journal of Clinical Endocrinology and Metabolism, found that children who were born to mothers who had had greater levels of n-6 PUFAs during pregnancy had greater fat mass.

Dr Nicholas Harvey, Senior Lecturer at the MRC Lifecourse Epidemiology Unit, University of Southampton, who led the research with Dr Rebecca Moon, Clinical Research Fellow, comments: "Obesity is a rising problem in this country and there have been very few studies of mother's fatty acid levels during pregnancy and offspring fat mass. These results suggest that alterations to maternal diet during pregnancy to reduce n-6 PUFAs intake might have a beneficial effect on the body composition of the developing child."

Results from the study also showed weaker associations between a mother's levels of n-3 PUFAs, more commonly known as omega 3 and found in fish oil, and muscle mass in their offspring the higher the level of n-3 the less fat and more muscle and bone in the baby.

This could suggest that a pregnancy supplementation strategy would be beneficial. However Dr Moon says: "n-6 and n-3 PUFAs seem to act in opposite directions on fat mass; previous trials have attempted to use n-3 supplementation to reduce fat mass, but our results suggest that such an approach might work best when combined with a reduction in dietary n-6 intake."

Professor Cyrus Cooper, Professor of Rheumatology and Director of the MRC Lifecourse Epidemiology Unit, University of Southampton adds: "This study forms part of a larger programme of research at the MRC Lifecourse Epidemiology Unit and University of Southampton in which we are seeking to understand how factors such as diet and lifestyle in the mother during pregnancy, and of the child in early life, influence a child's body composition and bone development. This work should help us to design interventions aimed at optimising body composition in childhood and later adulthood and thus improve the health of future generations."


Contact: Becky Attwood
University of Southampton

Related medicine news :

1. New Guidelines Urge Limiting Endoscopy for GERD
2. Limiting neurosurgery residents work hours hasnt decreased complication rates
3. Scripps Florida scientists develop new compound that reverses fatty liver disease
4. Analysis of conflicting fish oil studies finds that omega-3 fatty acids still matter
5. Girls with eating disorders regain healthy fatty acid levels when their weight normalizes
6. Pictures of Fatty, Sugary Foods May Spur Cravings
7. Fatty acid found in fish prevents age-related vision loss: U of A medical research
8. US Drug Watchdog Now Urges DePuy Pinnacle Metal Hip Recipients To Get A Blood Test and to Call Them For The Names Of The Best Lawyers If Their Metals Levels Are Elevated
9. High BPA Levels in Kids Linked to Risk for Heart, Kidney Damage: Study
10. US Drug Watchdog Now Urges All US Recipients of an All Metal Hip Implant to Get a Blood Test for Cobalt-Chromium Levels and They Offer Victims of a Failure Legal Contacts
11. Higher levels of obesity associated with increased risk of death
Post Your Comments:
(Date:10/13/2015)... , ... October 13, 2015 , ... ... a unique private messaging application, announced today a significant contract that will provide ... years. Independence plans to build on the growing success of its Relay program, ...
(Date:10/13/2015)... ... 2015 , ... A child without a healthy mouth is much more likely ... invisible aligner system, has joined with Global Dental Relief (GDR) to help ... treatment plan purchased, SmileCareClub will donate one clinic visit to a child in Kenya. ...
(Date:10/13/2015)... ... October 13, 2015 , ... ... kind product that targets the unique health needs of new moms. Postnatal ... Pregnancy Association ( ), utilizes Nordic Naturals’ exclusive, new, ultra-concentrated omega-3 ...
(Date:10/13/2015)... ... , ... Tempe Dental Care, a leading Tempe dentists’ office, celebrates offering gentle, ... for more than 5 years. A leading cause of emergency room visits, school ... is not timely. , Sedation dentistry provides an anxiety-free dental experience ...
(Date:10/13/2015)... (PRWEB) , ... October 13, 2015 , ... According to ... Rose suffered an orbital fracture when a teammate accidentally elbowed him in the left ... Rose's recent eye injury is just one of a series of setbacks, including a ...
Breaking Medicine News(10 mins):
(Date:10/13/2015)... 2015 Attracting mid- to large-sized medical device companies ... Baltimore into a major medical device ... Maryland Technology Enterprise Institute (Mtech) . ... place to support innovation hubs and a thriving medical device ... "This study is important because we believe Baltimore ...
(Date:10/13/2015)... Fla. , Oct. 13, 2015   Vigilant ... of solutions that aid in the early detection and ... has awarded Vigilant,s founder and CEO, Matthew H.J. ... Year Award, which recognizes an entrepreneur who has made ... life sciences industry in the leadership of ...
(Date:10/13/2015)... DURHAM, N.C. , Oct. 13, 2015   ... from the DESSOLVE I and II trials of its ... MiStent SES ® ) were presented at the ... held in San Francisco , October ... in interventional cardiovascular medicine. MiStent SES was designed to ...
Breaking Medicine Technology: