Navigation Links
Lilly and MacroGenics Announce Licensing and Collaboration Agreement
Date:10/18/2007

Lilly to Acquire Phase III Molecule Teplizumab for the Treatment of Type 1

Diabetes

Companies to Collaborate on the Development of Autoimmune Disease

Treatments

ROCKVILLE, Md., and INDIANAPOLIS, Oct. 18 /PRNewswire-FirstCall/ -- Eli Lilly and Company (NYSE: LLY) and MacroGenics, Inc. today announced that the two companies have entered into a global strategic alliance to develop and commercialize teplizumab, a humanized anti-CD3 monoclonal antibody, as well as other potential next generation anti-CD3 molecules for use in the treatment of autoimmune diseases. As part of the deal, Lilly will acquire the exclusive rights to the molecule. Teplizumab is currently being studied in the PROTEGE trial, a global pivotal Phase II/III clinical trial for individuals with recent-onset type 1 diabetes. MacroGenics will continue to oversee the PROTEGE trial.

Under the terms of the agreement, MacroGenics will receive an initial payment of $41 million, as well as $3 million in other committed funds. MacroGenics may also receive up to $200 million in potential development milestones for the type 1 diabetes indication. If teplizumab is successfully commercialized, MacroGenics may receive up to $250 million in potential sales milestones and would receive escalating royalties on sales commensurate with the current stage of development of the product. In addition, MacroGenics would have the option to co-promote teplizumab for certain indications in the U.S. Lilly may make an equity investment in MacroGenics of up to $10 million in the company's next private financing round or initial public offering. Lilly may also decide to pursue several additional indic
'/>"/>

SOURCE Eli Lilly and Company
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine news :

1. Animal insulin product to be discontinued by drug major Eli Lilly
2. Did Eli Lilly Turn Wily With Regard to Their Best-selling Schizophrenia Drug?
3. Eli Lilly Releases Digital Insulin Pen
4. OHSU Researchers Announce New Discovery
5. PM announces a new health care order for India
6. Partnership Between Diabetes India And Elsevier Announced
7. US Politicians Urge Movie Moghuls To Add Anti-Smoking Announcements
8. Ramdoss Announces Introduction of RCH-II
9. Britain Announces Third Transfusion Related Mad Cow Case
10. Gates Foundation Announces $287 Million In Grants Towards AIDS Vaccine
11. Tibet Announces the Dalai Lama’s Tour of South Americ
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... As part of Child Passenger Safety Week, which ... Amica Insurance is reminding parents and caregivers ... in the car. , According to a 2012 ... (NHTSA), 20 percent of drivers of child passengers admitted ... child restraints. However, 90 percent of those same drivers ...
(Date:9/16/2014)... PA (PRWEB) September 16, 2014 Former ... well today after undergoing successful heart transplantation surgery at ... Mr. Tekulve, who spent most of his 16-year baseball ... team as a commentator for Root Sports Pittsburgh, was ... transplant surgeon, Stephen Bailey, MD, surgical director of AGH’s ...
(Date:9/16/2014)... everyday, but that doesn,t mean the findings are put ... the neonatal mortality rate is 10 times higher than ... applying an inexpensive topical solution of chlorhexidine to cleanse ... by 24 percent, many Indian parents did not receive ... that we don,t have solutions to solve major societal ...
(Date:9/16/2014)... 2014 A team of researchers at Boston University ... new model to study the motion patterns of bacteria ... relate to communication within a bacterial colony. , The ... bacteria to a microcantilever a microscopic beam anchored ... thus coupling its motion to that of the bacteria. ...
(Date:9/16/2014)... 15, 2014A prospective study that compared patient-reported outcomes ... bone metastases demonstrates that single fraction radiation therapy ... radiation therapy (MFRT) when pain, function and quality ... today at the American Society for Radiation Oncology,s ... that improvements in patients, pain, function and degree ...
Breaking Medicine News(10 mins):Health News:Amica Offers Tips During Child Passenger Safety Week 2Health News:Former Pittsburgh Pirates Pitcher and Baseball Analyst Kent Tekulve Undergoes Successful Heart Transplant at Allegheny General Hospital 2Health News:Former Pittsburgh Pirates Pitcher and Baseball Analyst Kent Tekulve Undergoes Successful Heart Transplant at Allegheny General Hospital 3Health News:Pairing social networks with social motives to close the science gap 2Health News:Pairing social networks with social motives to close the science gap 3Health News:And so they beat on, flagella against the cantilever 2Health News:Single fraction RT as effective as multiple fraction RT for bone metastases 2Health News:Single fraction RT as effective as multiple fraction RT for bone metastases 3Health News:Single fraction RT as effective as multiple fraction RT for bone metastases 4
... rest of nation, , , TUESDAY, Feb. 10 (HealthDay News) -- A ... pain has more than doubled in that state since the early ... in the country as a whole. , "We were actually ... professor of medicine at the University of North Carolina and the ...
... of Americans age 65 and older have prescription drug coverage ... according to a University of Michigan analysis. And poor seniors ... , The analysis compares drug coverage among a nationally ... both in 2004 and after the Medicare Part D prescription ...
... National Leaders in the Effort to Improve Long-Term Care ... SCAN Foundation announced today that two of America,s leading ... for the elderly, Jennie Chin Hansen, R.N., ... named to The SCAN Foundation board of directors.Bruce Chernof, ...
... in Barry Willer,s office at the University at Buffalo was ... a relatively mild traumatic brain injury, and he was doing ... best efforts, the man,s wife described him to friends as ... Willer, UB professor of psychiatry and a specialist in traumatic ...
... Government contract; $28.5 million in contract year one- ... drives revenue for first half- Earnings per share ... Strong balance sheet with $2.1 million in cash, ... Feb. 10 Sharps Compliance Corp. (OTC Bulletin ...
... The Animal Research Minute is a daily report of ... Feb. 10 The Foundation for Biomedical Research (FBR) ... radio broadcast, The Animal Research Minute, nationally after experiencing ... Minute is an educational report of the day,s medical ...
Cached Medicine News:Health News:Chronic Low Back Pain Is on the Rise 2Health News:Chronic Low Back Pain Is on the Rise 3Health News:Most seniors have drug coverage, study shows 2Health News:The SCAN Foundation Names New Members to Its Board 2Health News:The SCAN Foundation Names New Members to Its Board 3Health News:Brain-injured patients can relearn emotions 2Health News:Brain-injured patients can relearn emotions 3Health News:Brain-injured patients can relearn emotions 4Health News:Sharps Compliance Corp. Reports Second Quarter Fiscal 2009 Results 2Health News:Sharps Compliance Corp. Reports Second Quarter Fiscal 2009 Results 3Health News:Sharps Compliance Corp. Reports Second Quarter Fiscal 2009 Results 4Health News:Sharps Compliance Corp. Reports Second Quarter Fiscal 2009 Results 5Health News:Sharps Compliance Corp. Reports Second Quarter Fiscal 2009 Results 6Health News:Sharps Compliance Corp. Reports Second Quarter Fiscal 2009 Results 7Health News:Sharps Compliance Corp. Reports Second Quarter Fiscal 2009 Results 8Health News:Sharps Compliance Corp. Reports Second Quarter Fiscal 2009 Results 9Health News:Sharps Compliance Corp. Reports Second Quarter Fiscal 2009 Results 10Health News:Sharps Compliance Corp. Reports Second Quarter Fiscal 2009 Results 11Health News:Sharps Compliance Corp. Reports Second Quarter Fiscal 2009 Results 12Health News:Sharps Compliance Corp. Reports Second Quarter Fiscal 2009 Results 13Health News:Foundation for Biomedical Research Announces National Distribution of Daily Radio Broadcast 2
(Date:9/16/2014)... Sept. 16, 2014 The Lupus Foundation of ... LLY ) today released results from UNVEIL: understanding the ... on the lupus journey and the challenges not only ... caregivers. The UNVEIL study, which involved over 1,000 people ... lupus has on all aspects of life including family, ...
(Date:9/16/2014)... Sept. 16, 2014 Imprimis Pharmaceuticals, Inc. (Nasdaq: ... to delivering high quality and novel medicines to physicians ... Executive Officer Mark Baum will be a ... Select Conference in New York City.  Mr. Baum will ... Dropless™ campaign in ophthalmology. The presentation is scheduled for ...
(Date:9/16/2014)... -- Relmada Therapeutics, Inc., (OTCBB: RLMD), a clinical-stage company developing ... today that it has entered into an agreement with ... of animal studies for levorphanol, the active ingredient of ... levorphanol.  Gavril Pasternak, MD, PhD, of MSKCC is the ... Pasternak said, "Levorphanol is a unique opioid analgesic that ...
Breaking Medicine Technology:"UNVEIL" Survey Reveals a Life Interrupted by Lupus 2"UNVEIL" Survey Reveals a Life Interrupted by Lupus 3"UNVEIL" Survey Reveals a Life Interrupted by Lupus 4"UNVEIL" Survey Reveals a Life Interrupted by Lupus 5Imprimis Pharmaceuticals to Present at Craig-Hallum Alpha Select Conference 2Imprimis Pharmaceuticals to Present at Craig-Hallum Alpha Select Conference 3Imprimis Pharmaceuticals to Present at Craig-Hallum Alpha Select Conference 4Relmada Therapeutics Enters Into Agreement with Memorial Sloan Kettering to Better Clarify Unique Mechanism of Action for LevoCap ER 2Relmada Therapeutics Enters Into Agreement with Memorial Sloan Kettering to Better Clarify Unique Mechanism of Action for LevoCap ER 3
... WORTH, Texas, March 22, 2012  The Board of Directors of ... innovator in advanced wound care solutions, announced today that Robert ... of the Company.  In addition, Scott A. Haire has resigned ... Executive Officer of the Company, and Deborah Jenkins Hutchinson has ...
... 22, 2012  Argon Medical Devices, Inc. announced today ... catheter, licensed from Rex Medical, LP, designed to ... treatments. "UltraStream provides clinicians with an ... life for their patients," commented George Leondis, President ...
Cached Medicine Technology:Wound Management Technologies Names Robert Lutz, Jr. as New CEO; Buys Back North American Distribution Rights for CellerateRX® Powder 2Wound Management Technologies Names Robert Lutz, Jr. as New CEO; Buys Back North American Distribution Rights for CellerateRX® Powder 3Argon Medical Devices Announces The Launch of a Unique New Chronic Hemodialysis Catheter 2
... ACS allows visualization of virtually the ... essentially coaxial positioning of the lens on ... detachment surgery, repairing giant retinal tears, diagnosing ... examining the peripheral retina in a vitreous ...
... somewhat higher magnification and increased ... best suited for detailed visualization ... Central Retinal is ideal for ... membrane peeling in proliferative vitreoretinopathy ...
... MiniQuad allows visualization of virtually the ... with essentially coaxial positioning of the ... excellent for retinal detachment surgery, repairing ... anterior proliferative vitreoretinopathy and for examining ...
... Lens enhances iridectomy procedures by providing ... conventional iridectomy lens designs) with exceptional ... this lens has been increased from ... The MagPlus comes standard with LaserWindow ...
Medicine Products: