Q4 Earnings per Share Reconciliation
------------------------------------
Q4 2007 Q4 2006
Expectations Results % Growth
------------ ------- --------
E.P.S. (reported) $.83 to $.88 $.12 NM
Eliminate estimated in-process
research & development charge
associated with MacroGenics
in-licensing .03 -
Eliminate product liability
charge - .42
Eliminate asset impairments,
restructuring and other special
charges - .31
Include pro forma as if the ICOS
acquisition was completed on
January 1, 2006 - (.03)
------------ -----
E.P.S. (pro forma adjusted) $.86 to $.91 $.82 5% to 11%
------------ -----
Full-Year Earnings per Share Reconciliation
--------------------------------------------
2007 2006
Expectations Results % Growth
------------ ------- ---------
E.P.S. (reported) $2.76 to $2.81 $2.45 13% to 15%
Eliminate estimated in-process
research & development charge
associated with MacroGenics
in-licensing .03 -
Eliminate product liability charge - .42
Eliminate asset impairments and
restructuring charges associated
with previously announced
manufacturing decisions
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