Navigation Links
Light Sciences Oncology Expands Development of Novel Targeted Drug Aptocine(TM) For Prostate Conditions With Start-Up of Phase 2 BPH Trial
Date:8/18/2009

BELLEVUE, Wash., Aug. 18 /PRNewswire/ -- Light Sciences Oncology, Inc. (LSO) today announced the treatment of the first patients in a Phase 2 clinical trial of its innovative targeted drug treatment Aptocine(TM) (talaporfin sodium) in Benign Prostatic Hyperplasia (BPH). The Phase 2 trial expands the Aptocine BPH development program on the basis of a Phase 1 study at escalating light doses. In the open-label Phase 2 trial, Aptocine is being tested for safety and efficacy in 40 patients with lower urinary tract symptoms (LUTS) due to BPH. Aptocine is also in two Phase 3 clinical trials for solid tumors in the liver as well as preclinical development for prostate cancer.

"Beyond Aptocine's late-stage development as a revolutionary treatment for solid tumors, we believe Aptocine also presents a new paradigm in treating benign neoplasms such as BPH," said LSO's President and CEO, Llew Keltner, M.D., Ph.D. "The Phase 2 BPH trial greatly widens the potential of Aptocine as a uniquely safe and effective targeted therapy."

Benign prostatic hyperplasia (BPH) is a nonmalignant enlargement of the prostate. The most common clinical manifestation of BPH is lower urinary tract symptoms, including urinary frequency, urgency, nocturia, decreased and intermittent force of urine stream and sensation of incomplete bladder emptying. BPH is a disease of the aging male population with a dramatic increase in incidence after the age of 50 years. The American Urological Association estimates that BPH will affect approximately 50 percent of men between the ages of 51 and 60 and up to 90 percent of men over the age of 80.

The primary outcome measures of the Aptocine Phase 2 BPH trial are safety, according to number and severity of adverse events, and preliminary effectiveness, according to evaluation using the International Prostate Symptom Score (IPSS) and Bother Score (BS). Complete information on study pr
'/>"/>

SOURCE Light Sciences Oncology, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine news :

1. EF Johnson Technologies, Inc. Highlights New Products at APCO 2009
2. August 2009 Mayo Clinic Womens HealthSource Highlights Health Care Dollars, Senses of Taste and Smell, and Emotional Eating
3. August 2009 Mayo Clinic Health Letter Highlights Herbal Supplements, Groin Rashes and Hand Arthritis
4. Lee County Schools "Lightens Up" by 2000 lbs and saves big
5. DUSA Pharmaceuticals Reports Second Quarter 2009 Corporate Highlights and Financial Results
6. Lumie Reveals Light Levels Received In July Are As Low As A Winter's Day
7. Sunlight May Cause Rash in Autoimmune Disease
8. DUSA Pharmaceuticals, Inc.(R) Announces Second Quarter Financial Results and Corporate Highlights Conference Call
9. 11th Annual Light the Night Date Announced
10. Class Action Notice for Minnesota Light Cigarette Litigation From Lommen, Abdo, Cole, King & Stageberg, P.A.
11. Smith & Nephew Highlights Advanced Wound Management Progress
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/25/2014)... Recently, Dylan Queen, a famous online company supplying women’s ... discounted prom dresses, most of which are priced under ... company, the promotion is valid until Jan. 22, 2015; ... UK market. , The prom dresses in this new ... A-line strapless, empire strapless chiffon, one shoulder, floor-length, V-neck ...
(Date:12/25/2014)... California (PRWEB) December 25, 2014 Helen ... home in Woodland Hills, California after an 8 year ... away on Christmas Eve evening in her home in ... aggressive metastatic breast cancer. , As ... over forty years, she pioneered and championed many of ...
(Date:12/25/2014)... THURSDAY, Dec. 25, 2014 (HealthDay News) -- The risk ... the holidays, so you need to be extra cautious, ... Day, we see a significant increase in patients coming ... at the Suffolk County Volunteer Firefighters Burn Center of ... celebrations should be full of joy, but if not ...
(Date:12/25/2014)... AngelWeddingDress.com tries its best to translate ... Today, the business has introduced its new collection of ... promotion. , The new prom outfits are guaranteed to ... lover. They are specially designed for 2015. Anyone who ... should visit its website before Jan. 26, 2015, the ...
(Date:12/25/2014)... 2014 Residents at Abernethy ... showed their generous spirit by providing holiday gifts ... Parenting Network- Grandparents Raising Grandchildren program. , Following ... the largest Christmas tree on the campus of ... residents of the Abernethy Village Association (AVA). Each ...
Breaking Medicine News(10 mins):Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 2Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 3Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 4Health News:Don't Let Burns Mar Your Holidays 2Health News:Angelweddingdress 2015 Prom Dresses Online Now 2Health News:Retirement Community Residents Make Impact During Holiday Season 2
... first intention molecule for the treatment of epilepsy in ... to an irreversible loss of vision. Serge Picaud, head ... Institut de la Vision have just discovered the origin ... limiting it. They have shown that vigabatrin provokes a ...
... of Medicine is convening the Summit on Integrative Medicine ... science, understanding, and progress of integrative medicine and explore ... the nation,s health care crisis. , Integrative medicine is ... patients and caregivers in the full range of physical, ...
... drive adoption DALLAS, Feb. 17 Providers of ... and personal health records (PHR) can generate over ... the disease management (DM) industry, according to Parks ... High-Tech Adoption . The international research firm cites ...
... Angeles Jewish Home are in it for the , Long ... Feb. 17 At the Los Angeles Jewish Home, one ... roof in the U.S. all agree on two things: They ... have the best ideas on just how to accomplish that ...
... have discovered that estrogen receptors are present in ... them to believe that anti-estrogen drug treatments may ... patients, overall outcome. , This research is being ... Endocrinology . , In estrogen-responsive cancerssuch as breast ...
... at The Medical College of Wisconsin in Milwaukee have linked ... and blood vessel disease in African Americans. Aldosterone is secreted ... kidneys. , The study appeared in the December 18, ... prevalence of high blood pressure, or hypertension, in African Americans ...
Cached Medicine News:Health News:Taurine: Key to the visual toxicity of an anti-epileptic drug for children? 2Health News:Taurine: Key to the visual toxicity of an anti-epileptic drug for children? 3Health News:IOM convenes Feb. 25-27 Summit on Integrative Medicine 2Health News:Personal Health Technology Spending to Exceed $460 Million in the Disease Management Sector in 2013 2Health News:Unique Group of 90-Year-Olds Share Top Ten Longevity Tips 2Health News:Unique Group of 90-Year-Olds Share Top Ten Longevity Tips 3Health News:Estrogen found to increase growth of the most common childhood brain tumor 2
(Date:12/24/2014)... and FARMINGTON, Conn. , ... (NYSE MKT: PTN), a biopharmaceutical company developing targeted, ... with significant unmet medical need and commercial potential, ... private placement of 2,050,000 shares of its common ... shares of its common stock.  Funds under the ...
(Date:12/24/2014)... DIEGO , Dec. 23, 2014 ResMed (NYSE: ... significant patent infringement action against Chinese medical device manufacturer BMC ... (ITC) ruled today that BMC,s masks listed below infringe ResMed,s ... or selling these masks in the United States ... iVolve N2 nasal mask , Willow nasal pillows mask ...
(Date:12/24/2014)... 2014  The American Diabetes Association is recommending ... people with diabetes and that all people with ... statins, in keeping with recent changes to guidelines ... College of Cardiology (ACC) and American Heart Association ... recent changes to the Association,s annual revised Standards ...
Breaking Medicine Technology:Palatin Completes $20 Million Equity and $10 Million Debt Financings 2Palatin Completes $20 Million Equity and $10 Million Debt Financings 3Palatin Completes $20 Million Equity and $10 Million Debt Financings 4ResMed Wins Patent Infringement Lawsuit Against Chinese Manufacturer BMC Medical 2New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 2New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 3New Standards of Care Provide Guidelines for Statin Use for People with Diabetes to Prevent Heart Disease 4
... flexible continuous monitoring, the M3 and M4 ... and neonatal patient care. M Series monitors ... includes a basic set of non-invasive parameters ... Optional Multi-Measurement Server extensions offer Mainstream or ...
... On-line Electronic Help (OLEH), an ... to critical anesthesia-related information. OLEH brings ... need it most right on ... care of the patient and ...
Compact networked patient monitors for flexible care....
... for flexible care settings., ,IntelliVue ... portability and measurement flexibility to match ... intermediate care environmentsat the patients side., ... in patient monitoring, IntelliVue has highly ...
Medicine Products: