Navigation Links
Lifetime trauma may speed progression of HIV, early death
Date:11/1/2007

CHAPEL HILL Even though effective drug cocktails have improved the outlook for many patients with HIV, disease progression, including the time from AIDS onset to death, varies widely from patient to patient. Now, a study led by the University of North Carolina at Chapel Hill School of Medicine provides new evidence that psychological factors play a role in disease progression.

The study is the first-known in the era of highly active antiretroviral therapy (HAART) for HIV to show that traumatic life events, such as physical or sexual abuse, are associated with faster mortality, both from AIDS-related and all causes.

Trauma and depression are common among people with HIV, and trauma and depression seem to have an effect on disease progression and mortality in HIV. Given that, it is critical that clinicians treating people infected with HIV recognize depression and trauma as risk factors for poor health outcomes, and thus screen and refer patients for psychological and psychiatric treatment when these problems are present, said Jane Leserman, Ph.D., professor of psychiatry and medicine and lead author of the study.

Some combination of cognitive behavioral therapy and medication might be very beneficial for patients experiencing severe or multiple types of trauma, Leserman said.

The study is published in the Nov. 1, 2007 edition of the American Journal of Psychiatry.

The researchers interviewed a group of 490 HIV infected patients in the rural southeast. Those who reported a greater number of categories of traumatic life events had faster death from all causes and from AIDS. More than half of the patients in the study experienced three or more lifetime traumas, and half had experienced physical or sexual abuse.

Unlike depression, the effects of which have been more widely studied in the era of HAART, with trauma, its possible to establish a time ordering of events.

In our study, these traumatic events occurred in most cases many years before the progression of the patients HIV. So its a more compelling argument for a causal effect of trauma, Leserman said. Trauma, most of it occurring two or more years before the study, seemed to continue to have a major impact on these patients.

Leserman hopes to study whether treating HIV patients for trauma results in better health outcomes. We need further study of trauma treatment in this population to find out if that attenuates some of the negative effects, she said.


'/>"/>

Contact: Les Lang
llang@med.unc.edu
919-843-9687
University of North Carolina at Chapel Hill
Source:Eurekalert

Related medicine news :

1. Sexual abuse affect health for a lifetime
2. Lifetime risk of heart failure increases
3. New Flu Vaccine Can Give Lifetime Protection
4. Encouraging a Lifetime of Healthy Skin Right from the Beginning
5. Estimated cost of lifetime AIDS treatment assessed to be $618,900
6. Drug Therapy can Reduce Preterm Births and Decrease Lifetime Medical Costs
7. Soon, a Vaccine That Could Keep All Types of Flu Away for Lifetime
8. Women, Younger Patients at Greater Lifetime Cancer Risk from CT Scan
9. One-third of Adults Have Had Some Form of Alcohol Use Disorder During Their Lifetimes
10. New guidelines for dealing with post traumatic stress disorder
11. New ways to help children with trauma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... D.C. (PRWEB) , ... March 23, 2017 , ... ... (LEAD Coalition) stands with all Americans facing life-altering and fatal diseases in opposition ... budget makes shortsighted decisions that would eviscerate care, services, and hope for the ...
(Date:3/23/2017)... ... , ... The Boulevard is honored to host Shriners and Masons Children’s Day ... in the Main West Entrance of The Boulevard (in front of JCPenney). , ... and each child with a parent or guardian will be photographed for free and ...
(Date:3/23/2017)... ... 23, 2017 , ... “Wounded Woman Be Ye Healed-Passing On A Legacy”: a ... Legacy” is the creation of published author, Desiree M Webb, a registered nurse, minister ... has been happily married to her husband, Paul, for over twenty-nine years. Desiree ...
(Date:3/23/2017)... ... March 23, 2017 , ... “The Trainer”: an electrifying ... author, Scotty, a fiction writer with an active imagination and an enthusiasm for action ... follows the tale of Wild Bill Hart, who sat looking at the thirty-three notches ...
(Date:3/22/2017)... ... March 22, 2017 , ... Cosmetic Town, ... first issue of its companion print magazine. The new magazine, scheduled for release ... to information provided by board-certified doctors from across the country. , According to ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)...   Casetabs , the pioneer surgery coordination application, ... the iPhone. With this new release, Casetabs is further ... physician offices, ambulatory surgery centers (ASCs) and hospitals. The ... even faster, more reliable access to case information. ... connect care teams so that surgeries can be coordinated ...
(Date:3/23/2017)... FRANCISCO , March 23, 2017 ... a value of USD 25.7 billion by 2025, according to ... are expected to grow at a faster rate due to ... rising awareness about various types of esthetic procedures used for ... these disorders. Hence, they are considered as the highest revenue ...
(Date:3/23/2017)... NeuroVive Pharmaceutical AB (Nasdaq Stockholm: NVP, OTCQX: NEVPF), ... of the Annual report for 2016 is now available on ... ... Pharmaceutical AB is a leader in mitochondrial medicine. The company ... preserve mitochondrial integrity and function in areas of unmet medical ...
Breaking Medicine Technology: