Navigation Links
Lifetime trauma may speed progression of HIV, early death
Date:11/1/2007

CHAPEL HILL Even though effective drug cocktails have improved the outlook for many patients with HIV, disease progression, including the time from AIDS onset to death, varies widely from patient to patient. Now, a study led by the University of North Carolina at Chapel Hill School of Medicine provides new evidence that psychological factors play a role in disease progression.

The study is the first-known in the era of highly active antiretroviral therapy (HAART) for HIV to show that traumatic life events, such as physical or sexual abuse, are associated with faster mortality, both from AIDS-related and all causes.

Trauma and depression are common among people with HIV, and trauma and depression seem to have an effect on disease progression and mortality in HIV. Given that, it is critical that clinicians treating people infected with HIV recognize depression and trauma as risk factors for poor health outcomes, and thus screen and refer patients for psychological and psychiatric treatment when these problems are present, said Jane Leserman, Ph.D., professor of psychiatry and medicine and lead author of the study.

Some combination of cognitive behavioral therapy and medication might be very beneficial for patients experiencing severe or multiple types of trauma, Leserman said.

The study is published in the Nov. 1, 2007 edition of the American Journal of Psychiatry.

The researchers interviewed a group of 490 HIV infected patients in the rural southeast. Those who reported a greater number of categories of traumatic life events had faster death from all causes and from AIDS. More than half of the patients in the study experienced three or more lifetime traumas, and half had experienced physical or sexual abuse.

Unlike depression, the effects of which have been more widely studied in the era of HAART, with trauma, its possible to establish a time ordering of events.

In our study, these traumatic events occurred in most cases many years before the progression of the patients HIV. So its a more compelling argument for a causal effect of trauma, Leserman said. Trauma, most of it occurring two or more years before the study, seemed to continue to have a major impact on these patients.

Leserman hopes to study whether treating HIV patients for trauma results in better health outcomes. We need further study of trauma treatment in this population to find out if that attenuates some of the negative effects, she said.


'/>"/>

Contact: Les Lang
llang@med.unc.edu
919-843-9687
University of North Carolina at Chapel Hill
Source:Eurekalert

Related medicine news :

1. Sexual abuse affect health for a lifetime
2. Lifetime risk of heart failure increases
3. New Flu Vaccine Can Give Lifetime Protection
4. Encouraging a Lifetime of Healthy Skin Right from the Beginning
5. Estimated cost of lifetime AIDS treatment assessed to be $618,900
6. Drug Therapy can Reduce Preterm Births and Decrease Lifetime Medical Costs
7. Soon, a Vaccine That Could Keep All Types of Flu Away for Lifetime
8. Women, Younger Patients at Greater Lifetime Cancer Risk from CT Scan
9. One-third of Adults Have Had Some Form of Alcohol Use Disorder During Their Lifetimes
10. New guidelines for dealing with post traumatic stress disorder
11. New ways to help children with trauma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... ... process to promote standards of excellence for the field of eating disorders, announces ... 22 – 25, 2018 in Orlando, Florida at the Omni Resort at ChampionsGate. ...
(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder of the ... a national organization of elder law and special needs planning attorneys. “Membership in ElderCounsel ... also provides a forum to network with elder law attorneys nationwide,” said Somekh. ...
(Date:10/13/2017)... ... 2017 , ... The Visiting Nurse Association (VNA) of Somerset Hills is proud ... and unique items from across the nation, this holiday-themed event will raise funds and ... the VNA. The boutique will be open Saturday, November 4 (10:00 a.m. – ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at ... of the most popular and least understood books in the Holy Scriptures, Revelation. The ... that have baffled scholars for centuries. Many have tossed it off as mere rubbish, ...
(Date:10/13/2017)... ... ... “The Journey: From the Mountains to the Mission Field”: the story of a ... “The Journey: From the Mountains to the Mission Field” is the creation of published ... all ages and currently teaches a class of ladies at her church, which she ...
Breaking Medicine News(10 mins):
(Date:10/5/2017)... 5, 2017  In response to the nationwide ... Maxillofacial Surgeons (AAOMS) released prescribing recommendations that urge ... used as a first-line therapy to manage a ... Recognizing the value and importance ... "Opioid Prescribing: Acute and Postoperative Pain Management" stresses ...
(Date:10/2/2017)... , Oct. 2, 2017  Eli Lilly and Company ... results for the third quarter of 2017 on Tuesday, ... call on that day with the investment community and ... The conference call will begin at 9 a.m. ... access a live webcast of the conference call through ...
(Date:9/28/2017)... Cohen Veterans Bioscience and Early Signal Foundation announce a ... sensors for real-time monitoring of patients with trauma-related and ... focused on disruptive health solutions for rare disorders and ... record and integrate behavioral, cognitive, physiological and contextual data. ... ...
Breaking Medicine Technology: