Navigation Links
Lifetime trauma may speed progression of HIV, early death
Date:11/1/2007

CHAPEL HILL Even though effective drug cocktails have improved the outlook for many patients with HIV, disease progression, including the time from AIDS onset to death, varies widely from patient to patient. Now, a study led by the University of North Carolina at Chapel Hill School of Medicine provides new evidence that psychological factors play a role in disease progression.

The study is the first-known in the era of highly active antiretroviral therapy (HAART) for HIV to show that traumatic life events, such as physical or sexual abuse, are associated with faster mortality, both from AIDS-related and all causes.

Trauma and depression are common among people with HIV, and trauma and depression seem to have an effect on disease progression and mortality in HIV. Given that, it is critical that clinicians treating people infected with HIV recognize depression and trauma as risk factors for poor health outcomes, and thus screen and refer patients for psychological and psychiatric treatment when these problems are present, said Jane Leserman, Ph.D., professor of psychiatry and medicine and lead author of the study.

Some combination of cognitive behavioral therapy and medication might be very beneficial for patients experiencing severe or multiple types of trauma, Leserman said.

The study is published in the Nov. 1, 2007 edition of the American Journal of Psychiatry.

The researchers interviewed a group of 490 HIV infected patients in the rural southeast. Those who reported a greater number of categories of traumatic life events had faster death from all causes and from AIDS. More than half of the patients in the study experienced three or more lifetime traumas, and half had experienced physical or sexual abuse.

Unlike depression, the effects of which have been more widely studied in the era of HAART, with trauma, its possible to establish a time ordering of events.

In our study, these traumatic events occurred in most cases many years before the progression of the patients HIV. So its a more compelling argument for a causal effect of trauma, Leserman said. Trauma, most of it occurring two or more years before the study, seemed to continue to have a major impact on these patients.

Leserman hopes to study whether treating HIV patients for trauma results in better health outcomes. We need further study of trauma treatment in this population to find out if that attenuates some of the negative effects, she said.


'/>"/>

Contact: Les Lang
llang@med.unc.edu
919-843-9687
University of North Carolina at Chapel Hill
Source:Eurekalert

Related medicine news :

1. Sexual abuse affect health for a lifetime
2. Lifetime risk of heart failure increases
3. New Flu Vaccine Can Give Lifetime Protection
4. Encouraging a Lifetime of Healthy Skin Right from the Beginning
5. Estimated cost of lifetime AIDS treatment assessed to be $618,900
6. Drug Therapy can Reduce Preterm Births and Decrease Lifetime Medical Costs
7. Soon, a Vaccine That Could Keep All Types of Flu Away for Lifetime
8. Women, Younger Patients at Greater Lifetime Cancer Risk from CT Scan
9. One-third of Adults Have Had Some Form of Alcohol Use Disorder During Their Lifetimes
10. New guidelines for dealing with post traumatic stress disorder
11. New ways to help children with trauma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2016)... Tysons Corner, VA (PRWEB) , ... May 03, ... ... a leading provider of innovative information technology (IT) solutions and digital consulting services ... its Enterprise Information Technology Services (EITS) Indefinite Delivery / Indefinite Quantity (ID/IQ) contract ...
(Date:5/3/2016)... ... May 03, 2016 , ... ... solutions, today announced the new SecureAccess feature for its CelestixEdge solution. CelestixEdge ... release will enable organizations to get the DirectAccess user experience on unsupported ...
(Date:5/3/2016)... ... May 03, 2016 , ... Dave Newberry, broker/owner of Newberry Realty, recently ... (PICC) annual fundraiser luncheon on Friday, May 20. “We have raised over $1,000 for ... drug abuse,” said Newberry. , PICC is a local Kent, WA, clinic that cares ...
(Date:5/2/2016)... ... May 02, 2016 , ... Those who may ... can find some useful information in a new video released by Serenity Recovery, ... which can be viewed on the Serenity Recovery YouTube channel, examines various treatment ...
(Date:5/2/2016)... ... May 02, 2016 , ... ... of innovation by partnering with college students at University of Colorado in Boulder ... senior level advertising campaigns class in the School of Journalism, who selected Beanfields ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... -- Intec Pharma Ltd. (NASDAQ: ... announced the appointment of Pnina Strauss-Levy as ... Strauss-Levy has 15 years of experience in clinical research ... record, having supported the advancement of several products through ... the United States and ...
(Date:5/3/2016)... , May 3, 2016 ... bekannt, dass sie einen entscheidenden Meilenstein durch ... Ein Aufruf zum Handeln, um Patientenresultate  bei ... trägt zu Fortschritten im Verständnis der Hepatischen ... ein Bewusstsein für Hepatische Enzephalopathie in der ...
(Date:5/2/2016)... NEW YORK , May 2, 2016 /PRNewswire/ ... Series B financing of Graybug Vision, Inc. Graybug ... to developing therapies that may transform care for ... and glaucoma.  Graybug Vision,s technology was first developed ... out into a startup venture. ...
Breaking Medicine Technology: