Navigation Links
Lifestyle changes linked to better outcomes after peripheral intervention

ANN ARBOR, Mich. Patients who quit smoking and took an aspirin and statin before undergoing treatment for blocked leg arteries were less likely to suffer a complication six months later, according to new research led by the University of Michigan Cardiovascular Center.

But few patients made the lifestyle changes and were on recommended medical therapy that can relieve leg pain and cramping associated with peripheral arterial disease, or PAD.

The registry findings were published online ahead of print in Circulation: Cardiovascular Interventions and reveal a dramatic underuse of basic medical treatment for PAD.

PAD is on the rise as people age and conditions such as diabetes, high blood pressure and obesity affect circulation. Peripheral vascular interventions, such as angioplasty, improves blood flow, specifically to the legs.

But before PVI, more than half of patients studied failed to receive minimal medical therapy, meaning that the patient quit smoking and took an aspirin and a statin -- drugs that can reduce blood clots and improve blood flow.

Even the doctors treating the patients for their blockages didn't always ensure that their patients went home from the hospital with a prescription.

At admission, 46.7 of patients were on aspirin, a statin and did not smoke; at discharge 71 percent were on both drugs and either did not smoke or still smoked but had smoking cessation counseling.

"The modest improvement in statin prescription before patients were discharged signifies a missed opportunity to provide a life-saving intervention for PAD patients," says lead study author P. Michael Grossman, M.D., an interventional cardiologist at the University of Michigan Cardiovascular Center.

Users of both aspirin and statins had a lower incidence of peripheral events such as repeat PVI, limb salvage surgery and amputation 7 percent compared to 15.8 percent.

The study included 1,357 patients identified in the Blue Cross Blue Shield of Michigan Cardiovascular Consortium Peripheral Vascular Intervention database. The BMC2 PVI registry includes patients from Michigan hospitals who underwent an intervention for treatment of PAD. Patients are often referred for PVI to manage leg pain and cramping a symptom that doctors call claudication.

More study is needed to determine reasons for the lack of medical therapy. Meanwhile the underuse of medical treatment known to reduce symptoms of claudication and adverse events is a "pressing quality gap," authors say.

"Although a considerable effort has been focused on the impact of guideline adherence in patients with heart attack and heart failure, there are currently no such national programs focused on patients with PAD," Grossman says.

"In Michigan, BMC2 PVI is actively working to improve the medical therapy and outcomes of patients with PAD who undergo revascularization procedures. Data such as this have allowed us to recognize the issues and give us the tools necessary to impact change," he says.


Contact: Shantell M. Kirkendoll
University of Michigan Health System

Related medicine news :

1. Healthy lifestyle during menopause may decrease breast cancer risk later on
2. Intensive Lifestyle Changes Keep Type 2 Diabetes at Bay
3. U.S. Lifestyles Thwarting Heart Health Progress: Report
4. Active lifestyle boosts brain structure and slows Alzheimer’s disease
5. How healthy are young peoples lifestyles?
6. Healthy outlook leads to a healthy lifestyle: study
7. Keeping Up a Healthy Lifestyle Pays Off in Added Years: Study
8. Lifestyle changes could prevent 400 cardiac events and 200 deaths in Swedish PCI patients
9. Healthy lifestyle reduces the risk of hypertension by two thirds
10. Global study suggests need for strategies to combat unhealthy lifestyles among the poor and the rich
11. Teens Lifestyle Choices Affect Their Blood Pressure
Post Your Comments:
(Date:10/13/2017)... , ... October 13, 2017 , ... ... be giving viewers the lowdown on sciatica in a new episode of "Success ... focuses on current events and innovation and investigates each subject in-depth with passion ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: ... “America On The Brink” is the creation of published author, William Nowers. ... As a WWII veteran, he spent thirty years in the Navy. Following ...
(Date:10/12/2017)... ... 12, 2017 , ... Planet Fitness, one of the largest and fastest growing ... open a flagship location in Covington, LA at 401 N. U.S. Highway 190, in ... to Office Depot in the Holiday Square shopping center. Its location allows it to ...
(Date:10/12/2017)... ... ... The American College of Medical Informatics (ACMI) will present the 2017 Morris ... of AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium is taking ... in the field of medical informatics, this prestigious award is presented to an individual ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... Restoration, has recently contributed a medical article to the newly revamped Cosmetic ... Mohebi’s article spotlights the hair transplant procedure known as Follicular Unit Extraction ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... IRVING, Texas , Oct. 11, 2017  Caris ... science focused on fulfilling the promise of precision medicine, ... Institute has joined Caris, Precision Oncology Alliance™ (POA) as ... leading cancer centers, the St. Jude Crosson Cancer Institute ... to advance the use of tumor profiling, making cancer ...
(Date:10/10/2017)... , Oct. 10, 2017   West Pharmaceutical Services, ... solutions for injectable drug administration, today shared the results ... Adapter for improving the intradermal administration of polio vaccines. ... Vaccination Summit in May 2017 by Dr. Ondrej ... Department, World Health Organization (WHO), and recently published in ...
(Date:10/4/2017)... Centers for Disease Control and Prevention (CDC), influenza vaccination should take ... communities across Massachusetts , Connecticut , ... through the end of the month. *Some exclusions apply ... ... by the end of October, according to the Centers for Disease Control ...
Breaking Medicine Technology: