Navigation Links
Lifestyle can alter gene activity, lead to insulin resistance
Date:6/18/2008

BETHESDA, Md. (June 18, 2008) A Finnish study of identical twins has found that physical inactivity and acquired obesity can impair expression of the genes which help the cells produce energy. The findings suggest that lifestyle, more than heredity, contributes to insulin resistance in people who are obese. Insulin resistance increases the chance of developing diabetes and heart disease.

The study, "Acquired obesity and poor physical fitness impair expression of genes of mitochondrial oxidative phosphorylation in monozygotic twins discordant for obesity," appears in the online edition of the American Journal of Physiology-Endocrinology and Metabolism, published by The American Physiological Society (www.the-aps.org).

The study was carried out by Linda Mustelin and Kirsi Pietilinen, of Helsinki University Central Hospital and the University of Helsinki; Aila Rissanen, Anssi Sovijrvi and Pivi Piiril of Helsinki University Central Hospital; Jussi Naukkarinen, Leena Peltonen and Jaakko Kaprio, University of Helsinki and National Public Health Institute; and Hannele Yki-Jrvinen of Helsinki University Central Hospital and Minerva Medical Research Institute.

Environment can influence genes

Recent studies have suggested that defects in expression of genes involved in the body's conversion of food to energy, known as mitochondrial oxidative phosphorylation, can lead to insulin resistance. The researchers wanted to know if defects in the expression of these genes are primarily a result of heredity or lifestyle. Because the twins in the study were identical, any differences that were found could be attributed to environmental factors, the researchers reasoned.

Twenty four pairs of identical twins, born in Finland between 1975 and 1979, took part in the study. Fourteen pairs (eight male and six female) were discordant for obesity, that is, one twin was obese, while the other w
'/>"/>

Contact: Christine Guilfoy
cguilfoy@the-aps.org
301-634-7253
American Physiological Society
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Mothers Know Best: NFL Moms Team With Eddie George to Showcase a Better Way to a Healthier Lifestyle
2. Eat Seafood, See Weight Loss: Recent Study Finds Another Reason to Eat Seafood for a Fit Lifestyle
3. Activate America(R) Brings Together YMCAs Nationwide to Promote Small Steps Toward a Healthier Lifestyle During America on the Move Week With the YMCA, September 22-29, 2007
4. YMCAs Activate America(R) Motivates More Than 1.3 Million People to Take 8 Billion Steps Toward a Healthier Lifestyle During America On the Move Week with the YMCA
5. Harvard Medical School: Healthy Lifestyle Will Boost Your Immune System Better Than a Handful of Supplements
6. Diet and lifestyle changes may help prevent infertility from ovulatory disorders
7. Diet, Lifestyle Changes Cut Some Infertility Risk
8. Elderly with high blood pressure less likely to get lifestyle modification advice from doctors
9. Demystifying Diabetes: The Complete Diabetes Lifestyle
10. Older Hypertension Patients Less Likely to Get Lifestyle Advice
11. it Girl Public Relations Adds O.N.I. New Organic Food Delivery Service to Its Lifestyle Division
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/23/2014)... (PRWEB) August 23, 2014 Summer vacation is ... will be back in session. While shopping for school supplies ... few weeks, Batzner encourages parents and students to also spend ... “Bed bugs are excellent hitchhikers and thrive in heavily populated ... “This makes classrooms and dorms the perfect settings for bed ...
(Date:8/22/2014)... IT manager of Top10BestSEOHosting.com is a web professional who ... recently announced that GoDaddy ( http://www.top10bestseohosting.com/go/GoDaddy.com/ ) is one ... is a popular supplier of cheap web hosting, and ... affordable rates. It offers three Linux shared hosting plans. ... the length of the contract. The longest contract length ...
(Date:8/22/2014)... On Friday, Aug. 22, Liberty University ... Sciences , hosting a ceremony in its courtyard attended ... and public welfare. , The 162-member inaugural class of ... (LUCOM) joined Liberty staff, faculty, and community leaders in ... new medical school. Classes began on Monday, Aug. 4. ...
(Date:8/22/2014)... Today, Zane Benefits, the #1 Online ... Health Plans. , According to Zane Benefits, employers are ... lower the cost of healthcare without reducing coverage for ... however, can be confusing. , The new guide contains ... main types of ABHPs. It also explains the ...
(Date:8/22/2014)... Top 10 Best SEO Hosting (Top10BestSEOHosting.com) has ... highly recommended FatCow ( http://www.top10bestseohosting.com/go/FatCow.com/ ) and BlueHost ... 10 Best SEO Hosting states, “It is hard ... Actually, these companies have outperformed their competitors on ... People can get the best web hosting at ...
Breaking Medicine News(10 mins):Health News:Expert Advice for a Bed Bug-Free School Year 2Health News:Liberty University Dedicates Its New Center for Medical and Health Sciences 2Health News:Liberty University Dedicates Its New Center for Medical and Health Sciences 3Health News:Liberty University Dedicates Its New Center for Medical and Health Sciences 4Health News:FatCow Reviews Released by Top10BestSEOHosting.com 2
... of alcohol abuse costs each Canadian $463 per year. ... abuse in Canada exceed those of cancer. Released today ... Avoidable Cost of Alcohol Abuse in Canada 2002 report estimates ... would result in cost savings of about $1 billion per ...
... much the way alcohol, Alzheimer,s do , , WEDNESDAY, June ... tissue loss in brain regions that help store memory, ... , "Our findings demonstrate that impaired breathing during sleep ... and thinking," principal investigator Ronald Harper, a professor of ...
... IT will Provide Immediate Access to Vital Patient ... ... Jim Traficant,vice president of Harris Corporation,s (NYSE: HRS ) ... Care,Administration (AHCA), and provided a patient,s perspective of healthcare,policy. Traficant projected ...
... of the 1000 Genomes Project announced today that three ... have joined the international effort to build the most ... a tool for medical research. The new participants are: ... Biosystems, an Applera Corp. business, Foster City, Calif.; and ...
... Ill. Primary snoring in children may have an ... obstructive sleep apnea (OSA), according to a research abstract ... 22nd Annual Meeting of the Associated Professional Sleep Societies ... colleagues at the University of Melbourne and Monash University, ...
... cognitive behavioral intervention for insomnia delivered via the Internet ... research abstract that will be presented on Wednesday at ... Professional Sleep Societies (APSS). , The study, authored by ... on 44 participants (mostly female) with an average age ...
Cached Medicine News:Health News:Save $1 billion and 800 lives 2Health News:Save $1 billion and 800 lives 3Health News:Sleep Apnea Linked to Memory Loss 2Health News:Harris Corporation's Jim Traficant Addresses Florida Agency for Health Care Administration 2Health News:3 sequencing companies join 1000 Genomes Project 2Health News:3 sequencing companies join 1000 Genomes Project 3Health News:3 sequencing companies join 1000 Genomes Project 4Health News:3 sequencing companies join 1000 Genomes Project 5Health News:Primary snoring in children impacts cardiovascular functioning 2Health News:Primary snoring in children impacts cardiovascular functioning 3Health News:A self-help program delivered online can improve insomnia in adults 2
(Date:8/21/2014)... , Aug. 21, 2014  Vermillion, Inc. (NASDAQ: ... on gynecologic cancers and women,s health, has appointed ... and Managed Markets. Ms. Bauzon has a ... expanding payer coverage for laboratory services companies. She has ... with PerkinElmer, Inc., where she held the position of ...
(Date:8/21/2014)... 2014  eRelevance Corporation ( www.erelevancecorp.com ), a ... it has completed integration with Nextech, a popular ... and Dermatology practices. "Integration allows our ... practices using Nextech," stated Bob Fabbio , ... from the EMR we are able to automatically ...
(Date:8/21/2014)... , Aug. 21, 2014  Publicis Groupe ... Hartley , Managing Partner and Healthcare Industry Group Leader, ... 100, which recognizes the most inspiring people in the ... leaders in research and development, marketing, technology, creativity, strategy ... in 2006 as a partner in its leading Rosetta ...
Breaking Medicine Technology:Vermillion Appoints Holly B. Bauzon as VP of Sales and Managed Markets 2eRelevance Corporation Integrates with Nextech Electronic Medical Records 2Shannon Hartley Shines in PharmaVOICE 100 2
... 18, 2012  Sotera Wireless, Inc. announced that it has ... Drug Administration (FDA) for the ViSi Mobile™   System, ... in hospitals. The clearance represents a major milestone in ... system, particularly for ambulatory hospital patients. "Continuous ...
... UBM Live has revealed further details of the ... Southeast Asia (SEA) 2012. Set to debut from 10-12 May ... is the first trade show and exhibition of its kind ... ASEAN region. CPhI SEA will provide a ...
Cached Medicine Technology:Sotera Wireless Reports FDA Clearance of ViSi Mobile™ System 2Leading Pharma Ingredients Event Debuts in Growing ASEAN Market 2Leading Pharma Ingredients Event Debuts in Growing ASEAN Market 3
Katena ophthalmic burr for polishing pterygiums, includes one round diamond burr and has an storage case....
Illuminated Trial Lens Set is an attractive set of trial lenses worked to a high standard of accuracy....
Trial Lens Sets....
... is the first ... to offer two kinds ... and taurine. Cleans, rinses, ... and conditions any soft ...
Medicine Products: