Navigation Links
Lifestyle May Counter Blood Pressure Genes
Date:6/16/2009

Smoking, drinking and more can override what you're born with, study finds

TUESDAY, June 16 (HealthDay News) --Being born with genes that predispose you to high blood pressure doesn't mean you're doomed to have it, a long-term study shows.

"It's been known for many years that blood pressure is affected by genes," said Dr. Nora Franceschini, an assistant professor of epidemiology at the University of North Carolina and lead author of a report on the study. "It's also known that lifestyle affects blood pressure. Now we are showing that they interact, and that the effect of those genes varies among individuals who have different behaviors."

It's an important finding because high blood pressure is a major risk factor for heart attack, stroke and other cardiovascular diseases. The study, reported online Tuesday in Circulation: Cardiovascular Genetics, "reinforces the message that lifestyle changes can alter the effect of genetics," Franceschini said.

That message comes from the Strong Heart Family Study, which has been looking at diabetes and high blood pressure among American Indians in Arizona, North and South Dakota and Oklahoma, an ethnic group in which the incidence of both is high. The study now includes more than 3,600 people aged 14 to 93.

The new report shows that different lifestyles and socioeconomic status influence the effect of inherited genetic patterns.

About 15 percent of the variation in diastolic blood pressure, the lower of the two numbers in a blood pressure reading, is because of genes, Franceschini said. The study linked the effects of three behavioral traits -- drinking, smoking and exercise -- with that of the genes. It also looked at education level, a socioeconomic factor.

The study found that genes for high blood pressure have a greater effect in smokers than nonsmokers, Franceschini said. It also found a similar effect for physical exercise. And it found that blood pressure among drinkers is affected by different genes than in people who quit drinking or never drank.

"Our study shows a comprehensive effect across multiple behaviors," she said.

The findings help answer whether genes alone determine high blood pressure, said Dr. Richard A. Stein, a professor of medicine and director of the urban community cardiology program at New York University and a spokesman for the American Heart Association.

"The answer is, not by a long shot," Stein said. "The actual effect is explained only by adding behavioral and socioeconomic factors into the equation. It is actually more how you live than what you are born with."

The next step in the study is an effort to identify the specific genes that interact with each of the behavioral traits to increase blood pressure, Franceschini said. Analysis of the entire genome "may allow us to identify the particular genes that account for the interaction," she said.

Another study reported in the same issue of the journal showed that small changes in measures aimed at controlling high blood pressure can produce significant results.

One such measure was distribution of wallet cards to track clinic visits, document blood pressure, update drug data and provide contact information, according to a report from the VA-Tennessee Valley Healthcare System.

More than 30,000 such cards were given to veterans in the system, and the result was a 4.2 percent improvement in blood pressure control, which translates into a significant reduction of cardiovascular risk, the report said.

More information

The U.S. National Heart, Lung and Blood Institute has more on high blood pressure.



SOURCES: Nora Franceschini, M.D., research assistant professor, epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, N.C.; Richard A. Stein, M.D., professor, medicine, and director, Urban Community Cardiology Program, New York University, New York City; June 16, 2009, Circulation: Cardiovascular Genetics


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Mothers Know Best: NFL Moms Team With Eddie George to Showcase a Better Way to a Healthier Lifestyle
2. Eat Seafood, See Weight Loss: Recent Study Finds Another Reason to Eat Seafood for a Fit Lifestyle
3. Activate America(R) Brings Together YMCAs Nationwide to Promote Small Steps Toward a Healthier Lifestyle During America on the Move Week With the YMCA, September 22-29, 2007
4. YMCAs Activate America(R) Motivates More Than 1.3 Million People to Take 8 Billion Steps Toward a Healthier Lifestyle During America On the Move Week with the YMCA
5. Harvard Medical School: Healthy Lifestyle Will Boost Your Immune System Better Than a Handful of Supplements
6. Diet and lifestyle changes may help prevent infertility from ovulatory disorders
7. Diet, Lifestyle Changes Cut Some Infertility Risk
8. Elderly with high blood pressure less likely to get lifestyle modification advice from doctors
9. Demystifying Diabetes: The Complete Diabetes Lifestyle
10. Older Hypertension Patients Less Likely to Get Lifestyle Advice
11. it Girl Public Relations Adds O.N.I. New Organic Food Delivery Service to Its Lifestyle Division
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Lifestyle May Counter Blood Pressure Genes
(Date:6/26/2016)... ... June 26, 2016 , ... On June 10-11, 2016, A Forever ... Cereal Festival and World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation ... as home to some of the world’s leading providers of cereal and other breakfast ...
(Date:6/26/2016)... Michigan (PRWEB) , ... June 26, 2016 , ... ... to fertility once they have been diagnosed with endometriosis. These women need a ... they also require a comprehensive approach that can help for preservation of fertility ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture ... said Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package ... Final Cut Pro X . Simply select a ProHand generator and drag it ...
(Date:6/25/2016)... , ... June 25, 2016 , ... On Friday, June ... a Bronze Wellness at Work award to iHire in recognition of their exemplary accomplishments ... of the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World Sickle ... chronic pain and the benefits of holistic treatments, Serenity Recovery Center of ... Sickle Cell Disease. , Sickle Cell Disease (SCD) is a disorder of the red ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... , June 27, 2016  VMS Rehab Systems, Inc. ... will take whatever measures required to build a strong ... which is currently listed on the OTC Markets-pink current ... Chairman and CEO, "We are seeing an anomaly in ... understand, not only by the Company, but shareholders and ...
(Date:6/24/2016)... June 24, 2016  Consumers have taken a ... have placed more emphasis on patient outcomes. ... programs in the pharmaceutical industry have evolved beyond ... pharmaceutical companies are focusing on becoming more patient-oriented ... products and services that improve health. ...
(Date:6/24/2016)... SAN FRANCISCO, Calif. , June 24, 2016 ... GBT ), a biopharmaceutical company developing novel therapeutics ... significant unmet needs, today announced the closing of ... shares of common stock, at the public offering ... shares in the offering were offered by GBT. ...
Breaking Medicine Technology: