Navigation Links
Lifestyle May Counter Blood Pressure Genes
Date:6/16/2009

Smoking, drinking and more can override what you're born with, study finds

TUESDAY, June 16 (HealthDay News) --Being born with genes that predispose you to high blood pressure doesn't mean you're doomed to have it, a long-term study shows.

"It's been known for many years that blood pressure is affected by genes," said Dr. Nora Franceschini, an assistant professor of epidemiology at the University of North Carolina and lead author of a report on the study. "It's also known that lifestyle affects blood pressure. Now we are showing that they interact, and that the effect of those genes varies among individuals who have different behaviors."

It's an important finding because high blood pressure is a major risk factor for heart attack, stroke and other cardiovascular diseases. The study, reported online Tuesday in Circulation: Cardiovascular Genetics, "reinforces the message that lifestyle changes can alter the effect of genetics," Franceschini said.

That message comes from the Strong Heart Family Study, which has been looking at diabetes and high blood pressure among American Indians in Arizona, North and South Dakota and Oklahoma, an ethnic group in which the incidence of both is high. The study now includes more than 3,600 people aged 14 to 93.

The new report shows that different lifestyles and socioeconomic status influence the effect of inherited genetic patterns.

About 15 percent of the variation in diastolic blood pressure, the lower of the two numbers in a blood pressure reading, is because of genes, Franceschini said. The study linked the effects of three behavioral traits -- drinking, smoking and exercise -- with that of the genes. It also looked at education level, a socioeconomic factor.

The study found that genes for high blood pressure have a greater effect in smokers than nonsmokers, Franceschini said. It also found a similar effect for physical exercise. And it found that blood pressure among drinkers is affected by different genes than in people who quit drinking or never drank.

"Our study shows a comprehensive effect across multiple behaviors," she said.

The findings help answer whether genes alone determine high blood pressure, said Dr. Richard A. Stein, a professor of medicine and director of the urban community cardiology program at New York University and a spokesman for the American Heart Association.

"The answer is, not by a long shot," Stein said. "The actual effect is explained only by adding behavioral and socioeconomic factors into the equation. It is actually more how you live than what you are born with."

The next step in the study is an effort to identify the specific genes that interact with each of the behavioral traits to increase blood pressure, Franceschini said. Analysis of the entire genome "may allow us to identify the particular genes that account for the interaction," she said.

Another study reported in the same issue of the journal showed that small changes in measures aimed at controlling high blood pressure can produce significant results.

One such measure was distribution of wallet cards to track clinic visits, document blood pressure, update drug data and provide contact information, according to a report from the VA-Tennessee Valley Healthcare System.

More than 30,000 such cards were given to veterans in the system, and the result was a 4.2 percent improvement in blood pressure control, which translates into a significant reduction of cardiovascular risk, the report said.

More information

The U.S. National Heart, Lung and Blood Institute has more on high blood pressure.



SOURCES: Nora Franceschini, M.D., research assistant professor, epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, N.C.; Richard A. Stein, M.D., professor, medicine, and director, Urban Community Cardiology Program, New York University, New York City; June 16, 2009, Circulation: Cardiovascular Genetics


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Mothers Know Best: NFL Moms Team With Eddie George to Showcase a Better Way to a Healthier Lifestyle
2. Eat Seafood, See Weight Loss: Recent Study Finds Another Reason to Eat Seafood for a Fit Lifestyle
3. Activate America(R) Brings Together YMCAs Nationwide to Promote Small Steps Toward a Healthier Lifestyle During America on the Move Week With the YMCA, September 22-29, 2007
4. YMCAs Activate America(R) Motivates More Than 1.3 Million People to Take 8 Billion Steps Toward a Healthier Lifestyle During America On the Move Week with the YMCA
5. Harvard Medical School: Healthy Lifestyle Will Boost Your Immune System Better Than a Handful of Supplements
6. Diet and lifestyle changes may help prevent infertility from ovulatory disorders
7. Diet, Lifestyle Changes Cut Some Infertility Risk
8. Elderly with high blood pressure less likely to get lifestyle modification advice from doctors
9. Demystifying Diabetes: The Complete Diabetes Lifestyle
10. Older Hypertension Patients Less Likely to Get Lifestyle Advice
11. it Girl Public Relations Adds O.N.I. New Organic Food Delivery Service to Its Lifestyle Division
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Lifestyle May Counter Blood Pressure Genes
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to ... to save lost souls in the Philippines. “The Journey: From the Mountains to the ... teacher of the Bible. She has taught all ages and currently teaches a class ...
(Date:10/12/2017)... ... 2017 , ... Planet Fitness, one of the largest and fastest growing franchisors ... a flagship location in Covington, LA at 401 N. U.S. Highway 190, in January ... Office Depot in the Holiday Square shopping center. Its location allows it to serve ...
(Date:10/12/2017)... ... October 12, 2017 , ... Asante, a ... health care, have expanded their existing home health joint venture through an agreement, ... been operating a joint venture home health company with Asante, delivering clinically integrated ...
(Date:10/12/2017)... Washington, D.C. (PRWEB) , ... October 12, 2017 , ... ... of their peers in Washington, D.C., for the 49th Congress of the International ... Ph.D ., Vice President of the Center for Cancer and Blood Disorders ...
(Date:10/12/2017)... BALTIMORE (PRWEB) , ... October 12, 2017 , ... ... average of $3,296 in property taxes a year. In some states—like New York, ... higher. , By contrast, many overseas retirement havens have extremely low property-tax rates, ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)...  EpiVax, Inc., a leader in the fields ... announced the launch of EpiVax Oncology Inc., a ... cancer vaccines. EpiVax has provided $500,000 in seed ... technologies to the new precision immunotherapy venture. Gad ... as Chief Executive Officer. Gad brings over 25 ...
(Date:9/22/2017)... 2017  As the latest Obamacare repeal effort moves ... (R-LA) and Lindsey Graham (R-SC) medical ... device industry is in an odd place.  The industry ... excise tax on medical device sales passed along with ... patients, increased visits and hospital customers with the funding ...
(Date:9/19/2017)... HistoSonics, Inc., a venture-backed medical device company developing a non-invasive, robotically assisted, platform therapy that ... developments today:   ... ... Tom Tefft ... Veteran medical device executive Josh Stopek , PhD, who has led R&D and ...
Breaking Medicine Technology: