Navigation Links
Lifestyle Doesn't Influence Genetic Risks in Breast Cancer
Date:6/2/2010

No evidence that known gene mutations interact with environmental factors, researchers say

TUESDAY, June 1 (HealthDay News) -- Despite prior research identifying both genetic risks for breast cancer as well as risks associated with lifestyle and environmental factors, a new British study reveals that the two types of risk pools appear to operate independently of one another.

The finding is based on analysis that looked for any evidence of an interaction between a dozen genetic mutations -- all associated with a small increase in breast cancer risk -- and 10 established environmental risk factors, which are factors linked to behavior or lifestyle. The results are reported in the June 2 online edition of The Lancet.

"We looked at whether lifestyle factors for breast cancer, such as use of HRT [hormone replacement therapy], alcohol consumption and reproductive history, influence the genetic risks," study author Dr. Ruth Travis, of the cancer epidemiology unit at the University of Oxford in the United Kingdom, said in a news release. "And the answer is that they do not."

Travis and her colleagues focused on 7,610 women who had been diagnosed with breast cancer, as well as nearly 10,200 women who did not have the disease. All of the women provided blood samples for genetic testing, as well as detailed information concerning their lifestyles.

DNA analyses looked for 12 common genetic variables, while the authors sifted through the collected lifestyle information in search of a specific group of environmental risk factors: age at first menstruation; number of births; age of mother at first birth; breast-feeding patterns; menopausal status; age at menopause; use of hormone replacement therapy; body-mass index; height; and alcohol consumption history.

Genetic risks and environmental risks did not appear to interact. In particular, the research team noted that despite previous indications to the contrary, hormone replacement therapy did not appear to have any significant impact on genetic risk factors.

More information

For more on breast cancer risk, visit the American Cancer Society.



-- Alan Mozes



SOURCE: The Lancet, news release, June 1, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Lifestyle Affects Survival in Non-Hodgkins Lymphoma
2. A more active lifestyle crucial for day-to-day function in COPD patients
3. Lifestyle factors significantly impact survival of non-Hodgkins lymphoma patients, study finds
4. SeaShine, LLC Announces the Launch of SeaShine Online Magazine, a Magazine for Women Who Positively Impact their Communities through Transparent Lifestyles
5. Free Anti-Aging Teleseminar Teaches People Key Lifestyle Changes To Maximize Longevity
6. Cell Science Systems Recruits Seasoned Executive to Head New Lifestyle Medicine & Nutritional Solution for Health Care Professionals
7. Introducing KePRO(TM) Engage Health - A Revolutionary Wellness & Lifestyle Management Company
8. Want to Live a Healthier Lifestyle? Now Theres an App for That, Too!
9. Gilsbar's Health & Lifestyle Management Program Wins First Place Award at the National Workforce Health Economics Summit
10. For Valentine's Day, Lifestyle Correspondent and Her Two Sets of Twins Show a Little Love Where Its Needed the Most
11. Moms Lifestyle in Early Pregnancy Affects Babys Size
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/8/2016)... D.C. (PRWEB) , ... February 08, 2016 , ... ... officially launched its newly redesigned website, federallabs.org . The site houses a ... or license available federal technologies through the process called technology transfer (T2). As ...
(Date:2/8/2016)... ... 2016 , ... A man who has struggled to quit smoking, a man who has struggled ... to find solutions to his problems – and he did. Now Nabat, a serial entrepreneur ... introduce his breakthrough inventions to the world and better people's lives. His own experience with ...
(Date:2/8/2016)... ... February 08, 2016 , ... The Bell Agency, ... the latest beneficiary of their ongoing community enrichment program. The current campaign fundraises ... schools. Donations are now being accepted at: http://www.angelsanddoves.com/donate.html . , Angels & ...
(Date:2/8/2016)... (PRWEB) , ... February 08, 2016 , ... ... that co-occur frequently. While a significant number of women and men with eating ... the trauma itself, that best predicts the development of an eating disorder. ...
(Date:2/8/2016)... ... 08, 2016 , ... TopConsumerReviews.com recently awarded their highest five-star rating to a ... derived from a cluster of melanin when exposed to sunlight. Although most moles are ... lifetime of embarrassment. Historically, mole removal has involved a painful, often expensive ...
Breaking Medicine News(10 mins):
(Date:2/8/2016)... -- Avista Pharma Solutions ("Avista Pharma") announced today that it ... (CFO). Mr. Setzer is a finance and operations executive ... within growing technology and life science companies. Prior to ... of Finance at INC Research, a publicly traded clinical ... Previously, Mr. Setzer served as CFO of Expression Analysis, ...
(Date:2/8/2016)... DUBLIN , Feb. 8, 2016 /PRNewswire/ ... announced the addition of the "Label-Free ... Global Forecasts to 2020" report to ... has announced the addition of the ... - Global Forecasts to 2020" report ...
(Date:2/8/2016)... YORK, Pa. , Feb. 8, 2016  Unilife Corporation ... developer and supplier of injectable drug delivery systems, today announced ... and six months ended December 31, 2015 after market close ... not scheduled a conference call to discuss these financial results.  ... About Unilife Corporation --> About Unilife ...
Breaking Medicine Technology: