Navigation Links
Licorice May Block Absorption of Organ Transplant Drug
Date:3/25/2009

Study finds potential interaction with cyclosporine could lead to fatal complications

TUESDAY, March 24 (HealthDay News) -- People taking the immunosuppressant cyclosporine should avoid consuming licorice because it may weaken the drug's effectiveness and possibly lead to deadly consequences, new research suggests.

Chemists in Taiwan report that lab rats taking cyclosporine -- commonly used to help prevent organ rejection in transplant patients -- who were feed licorice or its main active ingredient, glycyrrhizin, did not absorb the medication well. For a transplant patient on cyclosporine, lowered levels of the medication could lead to rejection of the new organ, followed by illness and even death, said the researchers, who were to present their findings Tuesday at the American Chemical Society's annual meeting in Salt Lake City.

"I would suggest that transplant patients avoid taking licorice," researcher Pei-Dawn Lee Chao, a chemist at China Medical University in Taichung, Taiwan, said in an American Chemical Society news release.

The researchers, who are trying to determine why licorice interfered with the drug's absorption, said they didn't know how much licorice might cause a toxic reaction in humans.

Cyclosporine is also used to treat rheumatoid arthritis, juvenile myositis and various skin conditions, and it is known to interact poorly with some medicines, foods and herbs. St. John's wort, onions and ginger, for example, can also lower cyclosporine levels in the blood, while grapefruit juice can sending cyclosporine levels soaring.

Licorice has been reported to possibly interfere with high blood pressure medications, aspirin, anti-inflammatory drugs, insulin and oral contraceptives. The herb has been popular in folk medicine for centuries and is used by some combat stomach ulcers, bronchitis and sore throat. Because of its sweetness, glycyrrhizin is sometimes used in candy, teas and other foods.

More information

The U.S. National Center for Complementary and Alternative Medicine has more about licorice.



-- Kevin McKeever



SOURCE: American Chemical Society, news release, March 24, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Licorice compound offers new cancer prevention strategy
2. Licorice extract provides new treatment option for canker sores
3. Hebrew University scientist develop technique for eliminating reblockage of arteries
4. Drug blocks two of worlds deadliest emerging viruses
5. Drug blocks 2 of worlds deadliest emerging viruses
6. United States Files Suit Against Missouri-Based Pharmaceutical to Block Manufacturing and Shipping of Unapproved Drugs
7. Market for Niche Blockbusters Promises an Attractive Future for Large Pharmaceutical Companies, Indicates Frost & Sullivan
8. NLRB Blocks New Organizations Attempts to Divide UHW; SEIU UHW Committed to Securing Good Contracts With Members
9. Blocking protein leads to fewer, smaller skin cancer tumors
10. Beta Blocker Blocks Feelings of Bad Memories
11. USC study finds that green tea blocks benefits of cancer drug
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Licorice May Block Absorption of Organ Transplant Drug
(Date:6/26/2016)... ... 2016 , ... PawPaws brand pet supplements owned by Whole Health ... the health of felines. The formula is all-natural and is made from Chinese herbs ... Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia ...
(Date:6/26/2016)... ... June 26, 2016 , ... ... have been diagnosed with endometriosis. These women need a treatment plan to not ... comprehensive approach that can help for preservation of fertility and ultimately achieving a ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery services, ... Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. , Dr. ... skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey was ...
(Date:6/25/2016)... ... , ... "With 30 hand-drawn hand gesture animations, FCPX users can easily customize ... Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn pictures into ... Simply select a ProHand generator and drag it above media or text in the ...
(Date:6/25/2016)... , ... June 25, 2016 , ... As a lifelong ... Cum Laude and his M.D from the David Geffen School of Medicine at UCLA. ... to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)...  In a startling report released today, National Safety Council ... a comprehensive, proven plan to eliminate prescription opioid overdoses. ... states are tackling the worst drug crisis in recorded U.S. history, ... Kentucky , New Mexico , ... the 28 failing states, three – Michigan , ...
(Date:6/23/2016)... Bracket , a leading clinical trial technology ... outcomes platform, Bracket eCOA (SM) 6.0, at the 52 ... 30, 2016 in Philadelphia , Pennsylvania.  A ... product of its kind to fully integrate with RTSM, will ... 6.0 is a flexible platform for electronic clinical outcomes assessments ...
(Date:6/23/2016)... 23, 2016  Guerbet announced today that it has ... Horizon Award . One of 12 suppliers ... for its support of Premier members through exceptional local ... and commitment to lower costs. ... of our outstanding customer service from Premier," says ...
Breaking Medicine Technology: