Navigation Links
Levosimendan improves event free survival by 50 percent in end-stage heart failure
Date:5/27/2013

Lisbon, 27 May 2013: Ambulatory levosimendan improves event free survival by 50% compared to placebo, according to results from the LevoRep Study presented today during the late breaking trial session1 of the Heart Failure Congress 2013. In a second study, the third generation mineralocorticoid receptor antagonist (MRA) BAY 94-8862 showed improved potassium and kidney tolerance in heart failure patients with chronic kidney disease (CKD).

Heart Failure 2013 is the main annual meeting of the Heart Failure Association of the European Society of Cardiology and is being held 25-28 May in Lisbon, Portugal (1)

The prevalence of end-stage heart failure is increasing significantly and is associated with frequent hospital admissions and high costs. LevoRep is the largest trial of repetitive ambulatory administration of an inotrope in end-stage heart failure. The study focused on the safety and efficacy of levosimendan in an ambulatory setting.

LevoRep was a multicentre study in which 120 patients with end-stage heart failure were randomised to receive biweekly 0.2 mcg/kg/min levosimendan for 6 hours over 6 weeks or placebo. The study met its secondary endpoints and showed that ambulatory levosimendan was safe and improved event free survival by 50% compared with placebo. However, the study failed to show significant improvements in functional capacity and quality of life which were the primary endpoints.

Presenter Dr Gerhard Poelzl (Austria) said: "Future studies with more patients and higher dosing or higher repetition frequencies of levosimendan in an outpatient setting could show positive results for the primary endpoints. The improvement in event-free survival shown in this study may revive an old concept of ambulatory treatment of end-stage heart failure patients which has been largely dismissed because of the excessive mortality with in
'/>"/>

Contact: Jacqueline Partarrieu
press@escardio.org
33-492-947-756
European Society of Cardiology
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Clinical insight improves treatment with new lung cancer drug
2. Normalizing tumor blood vessels improves delivery of only the smallest nanomedicines
3. Exercise improves quality of life during breast cancer treatment
4. Early treatment improves outcomes in rare, often undiagnosed form of encephalitis
5. NYUCNs Dr. Laura Wagner: Study finds accreditation improves safety culture at nursing homes
6. Brief training program improves resident physicians empathy with patients
7. A nurse practitioner-driven palliative care intervention improves cancer patients quality of life
8. Oxytocin improves brain function in children with autism
9. Nordic walking improves health of heart failure patients
10. Donor aortic graft improves reconstruction after partial laryngectomy
11. Vitamin C improves pulmonary function in newborns of pregnant smoking women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... 23, 2015 Recently, Weddingshe.com has added many ... has announced its highest annual revenues in the past three ... popular glamorous wedding dresses. , According to the sales manager ... dress promotions for them in 2015. This point can be ...
(Date:1/22/2015)... Payday lending practices in four southern ... financial distress to the states that permit them, according ... Center on Race and Wealth. , While they generate ... loans at the same time substantially depress economic activity, ...
(Date:1/22/2015)... January 22, 2015 JJsHouse.com is a famous ... Today, the business announces its latest collection of wedding ... “The most important issue is the wedding dress on your ... in a woman’s life. Every bride wants to find the ...
(Date:1/22/2015)... Richmond, VA (PRWEB) January 22, 2015 ... the power at the Science Museum of Virginia. Wicked ... 24. , Wicked Plants unearths 75 poisonous, carnivorous and ... traverse through each room to uncover the biochemical, physical ...
(Date:12/26/2014)... 26, 2014 It is said that nothing ... Today, UWDress.com, the famous wedding dress supplier, shows its ... site-wide cocktail gown promotion. , UWDress.com’s navy cocktail gowns ... they come in high fashion styles. Simple dresses in bright ...
Breaking Medicine News(10 mins):Health News:Weddingshe Announces A Special Offer On Its Popular Glamorous Wedding Dresses 2Health News:Howard University Spotlights the Economic Impact of Payday Lending in Southern States 2Health News:Find The Most Suitable Wedding Dress At JJsHouse.com 2Health News:Wicked Plants are taking over the Science Museum of Virginia 2Health News:UWDress.com Shows Its New Navy Cocktail Dresses For 2015 2
... HealthDay Reporter , TUESDAY, Dec. 7 (HealthDay News) ... more likely to take up smoking than teens whose parents ... research. , In fact, the study authors estimated that ... movies, their risk of starting to smoke could drop two ...
... News) -- Teens who have health problems have fewer friends ... than they actually are, new research shows. U.S. researchers ... a 1994-1996 survey that asked them about their health and ... health as "excellent" or "very good." The rest of the ...
... ER? A group of computer engineers at Vanderbilt ... available to create robot assistants that can perform effectively ... specialists in emergency medicine at Vanderbilt University Medical Center ... groups have formed an interdisciplinary team to explore the ...
... The John Theurer Cancer Center at Hackensack University Medical ... annual meeting of the American Society of Hematology (ASH) ... ASH meeting is the world,s leading scientific gathering of ... the 40 abstracts from the John Theurer Cancer Center ...
... School of Hygiene & Tropical Medicine (LSHTM) has contributed to ... the occurrence of several common cancers. The study is published ... started and carried out by Professor Peter Rothwell in Oxford, ... of aspirin. These have been primarily concerned with reducing heart ...
... A study published in the December issue of The ... tomography/computed tomography (PET/CT) scans as a potentially useful tool ... with radiofrequency ablation (RFA). RFA, which uses localized thermal ... an alternative treatment for patients unable to undergo surgery ...
Cached Medicine News:Health News:Watching R-rated Movies Ups Odds of Teens Smoking 2Health News:Watching R-rated Movies Ups Odds of Teens Smoking 3Health News:Teens' Poor Health Linked to Fewer Friends 2Health News:Developing robots for the hospital emergency room 2Health News:Developing robots for the hospital emergency room 3Health News:John Theurer Cancer Center presents studies on promising therapies for aggressive blood cancers 2Health News:John Theurer Cancer Center presents studies on promising therapies for aggressive blood cancers 3Health News:John Theurer Cancer Center presents studies on promising therapies for aggressive blood cancers 4Health News:John Theurer Cancer Center presents studies on promising therapies for aggressive blood cancers 5Health News:John Theurer Cancer Center presents studies on promising therapies for aggressive blood cancers 6Health News:John Theurer Cancer Center presents studies on promising therapies for aggressive blood cancers 7Health News:Low-dose aspirin reduces death rates from range of cancers by between 20 and 30 percent 2Health News:Fewer guessing games for lung cancer patients 2
(Date:1/22/2015)... Jan. 22, 2015  Profil Institute for Clinical Research, Inc., ... obesity, announced today a new textbook,  Translational Research Methods ... Springer, a leading global scientific publisher. The ... techniques for use in early phase clinical studies of ...
(Date:1/22/2015)... , Jan. 22, 2015 Research and Markets ... "Infectious Disease Diagnostics Market by Product, Application, Technology, ... to their offering. , The infectious disease ... 7.9% to reach $18,156.2 million by 2019 from $12,422.8 ...
(Date:1/22/2015)... DUBLIN , Jan. 22, 2015 Research and Markets ... "Allergy Diagnostics Market by Allergen Source, Product & by ... their offering. The global allergy diagnostics market ... to grow at a CAGR of 12.67%, to reach $2,230.72 ...
Breaking Medicine Technology:New Textbook "Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug Development" Provides Critical Review Of Current And Emerging Clinical Investigation Methods 2New Textbook "Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug Development" Provides Critical Review Of Current And Emerging Clinical Investigation Methods 3Global Infectious Disease Diagnostics (Instruments, Reagents, Services, Software) Market - Forecast to 2019 2Global Infectious Disease Diagnostics (Instruments, Reagents, Services, Software) Market - Forecast to 2019 3Global Allergy Diagnostics (Immunoassay Analyzer, Luminometer, Assay Kit, Consumables) Market - Forecast to 2019 2Global Allergy Diagnostics (Immunoassay Analyzer, Luminometer, Assay Kit, Consumables) Market - Forecast to 2019 3
... ATLANTA, Oct. 3, 2011 As 73% of all ... 300 beds or less, collectively these hospitals account for ... well-located access to emergency and medical care, the role ... Americans. To sustain community healthcare with quality physicians and ...
... Optimer Pharmaceuticals, Inc. (NASDAQ: OPTR ) today ... Newsmakers in the Biotech Industry conference on Friday, October 21 ... ) A live audio webcast of ... the Company,s website at www.optimerpharma.com .  Replays of the ...
Cached Medicine Technology:Craneware Supports Forward-Thinking Community Hospital Executives to Strengthen U.S. Community Healthcare's Business Performance 2Craneware Supports Forward-Thinking Community Hospital Executives to Strengthen U.S. Community Healthcare's Business Performance 3
All Day Comfort for the Lower Body...
Designed for special procedures, this Wrap-Around apron has .50mm Pb in the front and .25mm Pb in the back. The velcro fasteners are adjustable to provide the most comfortable fit....
Setting a new standard in protective apparel. The unique, patented Cool-Tech™ mesh-back design fits the natural contour of the body while reducing the amount of weight carried on the shoulders ...
Protect your thyroid with a personal Thyroid Shield. While other shields have a rough, abrasive bias binding edging the neck, these have a softer, smoother turned seam that helps protect your neck fr...
Medicine Products: