Navigation Links
Leukemia Risk From MS Drug May Be Up
Date:4/30/2009

ds without symptoms. Eventually the disease can lead to loss of vision and paralysis.

Because research has shown that the drug can cause heart failure at high cumulative dosages as well as acute leukemia, doctors exercise caution when giving it to patients, said Patricia O'Looney, vice president of biomedical research for the National Multiple Sclerosis Society.

But the difficulty, she said, is that there are few other options for people with secondary progressive MS, and quality of life has to be balanced with risk of heart damage and leukemia.

"That's the frustrating part," O'Looney said. "When someone is reaching a very progressive form of the disease, and other drugs aren't working, we desperately need something in the clinical care of patients to try to help them. But there's no question about it. Novantrone is a strong drug, and with strong drugs, there are side effects."

Mitoxantrone is given in an IV infusion, usually in doses of 10 to 20 milligrams spaced about thee months apart.

Current U.S. guidelines call for people to receive a total lifetime dose of no more than 140 mg, O'Looney said.

People in the Italian study had received substantially less. Those who developed leukemia were given an average of 82 mg, compared with 63 mg for those who did not develop leukemia.

The leukemia occurred an average of three years after the first use of the drug and an average of 18 months after treatment had ended, according to the study.

"It is vital that all MS patients treated with mitoxantrone undergo prolonged and careful hematological follow-up to check for acute leukemia," Martinelli said.

In a second study to be presented at the meeting in Seattle, researchers found that adding the steroid methylprednisolone to treatment with interferon beta-1a (Avonex), a standard part of MS drug therapy, may reduce the amount of disease activity more than using the MS drug alone.

<
'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Risk of Leukemia with Multiple Sclerosis Drug Higher Than Thought
2. Researchers find drug that inhibits acute leukemia cell growth
3. Vince Papale and Eagles Fly for Leukemia Tee Up for a Cure at May 4, 2009 Celebrity Golf Classic and Auction
4. The Nations Triathlon to Benefit The Leukemia & Lymphoma Society is Sold Out But Theres Still a Way In!
5. Mayo Clinic-led researchers confirm gene variants associated with the most common adult leukemia
6. Experimental agents may prevent radiation-induced leukemia
7. New biomarker may predict leukemia aggressiveness
8. Success of Colorful School Supply Collection Inspired by Leukemia Patient Kicks off Second Year
9. Enhancing the effects of the drug used to treat chronic myeloid leukemia
10. Scientists Identify Key Gene That Protects Against Leukemia
11. Families of Children Affected by Leukemia Get Boost of Support Thanks to Gift From Chrysler Jeep Superstores
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Leukemia Risk From MS Drug May Be Up
(Date:8/30/2014)... 2014 Patients suffering from vitiligo can ... a new review published by Daily Gossip. , ... so there is no wonder that numerous sufferers search ... Vitiligo Treatment is one of the most appreciated such ... promises to stop the spread of this disorder immediately, ...
(Date:8/30/2014)... 30, 2014 The Plastic Surgery Group ... Jersey and even in the U.S. to provide clients ... off of patients’ waists with deep-tissue heating. , Unlike ... sections, Vanquish is more inclusive to target large sections ... comfortably under panels about one inch away from their ...
(Date:8/30/2014)... 30, 2014 The establishment and ... has been one of the main strategies of ... a positive impact around the world. , Architecturally ... top trained executives and trainers deliver L. Ron ... Vital statistics demonstrate that significant reduction in ...
(Date:8/30/2014)... Richmond, VA (PRWEB) August 30, 2014 Seniors ... several articles recently that focus on Alzheimer’s Disease, Dementia, ... recently revealed to the public of being diagnosed with the ... his latest movie, “I’ll Be Me”. The movie, out ... life while focusing on his diagnosis of the disease – ...
(Date:8/30/2014)... Randy Dotinga HealthDay ... About one in five patients operated on for broken bones ... surgery, a new study finds. Less-educated patients and ... more likely to be "doctor shoppers," said study lead author ... Ky. Overall, he said, the study suggests that doctors aren,t ...
Breaking Medicine News(10 mins):Health News:Natural Vitiligo Treatment Review Exposes Fast Method for Skin Repigmentation 2Health News:NJ Top Docs Presents, The Plastic Surgery Group 2Health News:Cradle of Aviation Museum Opens Its Doors to Long Island Scientologists 2Health News:Alzheimer’s Disease and Dementia Focus on Retirement Website SeniorsGuideOnline.com 2Health News:'Doctor-Shopping' for Painkillers Common After Broken-Bone Surgery, Study Finds 2Health News:'Doctor-Shopping' for Painkillers Common After Broken-Bone Surgery, Study Finds 3
... 6 Prescription pediatric drugs represent,an enormous market, with ... growth is forecast at a modest 3.2%, reaching $43,billion ... share of 11.7%, is,expected to achieve the highest growth ... Kalorama Information,s new report The World Market for,Pediatric Drugs., ...
... Medical Solutions, Inc.,(Rising), a leading medical cost ... Index (PCI) "Top Growth Company" list for ... http://www.newscom.com/cgi-bin/prnh/20080206/AQW030LOGO-b ), (Logo: http://www.newscom.com/cgi-bin/prnh/20080206/AQW030-a ... Inc. ( http://www.entrex.net ), is a,proprietary benchmarking ...
... restatement of Beth Israel Deaconess,Medical Center audit, ... apply the same Sarbanes-Oxley standards used by Massbank ... the board of Beth Israel,Deaconess Medical Center (BIDMC), ... East. Bufferd is also the retired treasurer of,Massachusetts ...
... The Female Health Company,(Amex: FHC ) ... conference call,to discuss its operating results for the ... (EST) on Wednesday, February 13, 2008. The Company ... earlier the same day., Shareholders and other ...
... Medical cost increases for,employers throughout the world ... according to a poll of insurance companies conducted ... The poll also found,that, in a vast majority ... rate of inflation., Nearly three-fourths (71 percent) ...
... A new statewide survey,released today shows that ... tax revenue for programs to prevent kids,from starting ... poll of 500 Virginia voters was released today ... Lung Association and,the Campaign for Tobacco-Free Kids. The ...
Cached Medicine News:Health News:Diabetes, Growth Disorders Drive Sales of Pediatric Hormone Drugs 2Health News:Rising Medical Solutions, Inc. Ranks Fifth on the Private Company Index (PCI) 'Top Growth Companies' List 2Health News:Massbank Board Member Should Use Sarbanes-Oxley Disclosure Rules in Non-Profit Role, Asserts 1199 SEIU 2Health News:The Female Health Company Schedules First Quarter Conference Call for February 13, 2008 2Health News:Medical Cost Increases to Accelerate Worldwide Over Next Five Years, Watson Wyatt Poll Finds 2Health News:Medical Cost Increases to Accelerate Worldwide Over Next Five Years, Watson Wyatt Poll Finds 3Health News:New Poll Shows Virginia Voters Overwhelmingly Favor Funding for Tobacco Prevention 2Health News:New Poll Shows Virginia Voters Overwhelmingly Favor Funding for Tobacco Prevention 3
(Date:8/29/2014)... , Aug. 29, 2014 Research and ... Disorders Drug Pipeline Insight 2014" report to their offering. ... in US is one of the largest segments of pharmaceuticals ... alarming rate, while the available therapies were unable to meet ... in the market for CNS disorder, especially over the past ...
(Date:8/29/2014)... Research and Markets has announced the addition ... Pharmaceutical Equipment Market in China, 2014-2018" report to ... Forecast of Pharmaceutical Equipment Market in China ... pharmaceutical equipment industry in the aspects of current ... performance of domestic major enterprises, as well as offers ...
(Date:8/29/2014)... According to the new ... (Equipment, Reagent, Primer, Probe, Custom Oligos), End-User (Research, ... Synthesis, NGS, DNA, RNAi) - Global Forecast to ... Market is expected to reach $1,712.1 Million by ... a CAGR of 9.8% from 2014 to 2019.. ...
Breaking Medicine Technology:US CNS Disorders Drug Pipeline Insight 2014 2Research and Development Trend Forecast of Pharmaceutical Equipment Market in China, 2014-2018 2Oligonucleotide Synthesis Market Worth $1,712.1 Million by 2019 2Oligonucleotide Synthesis Market Worth $1,712.1 Million by 2019 3Oligonucleotide Synthesis Market Worth $1,712.1 Million by 2019 4
... HAMILTON, N.J., Sept. 14 MedAvante, Inc., the leader ... that the U.S. Food and Drug Administration (FDA) has ... psychiatric medication including primary outcome data collected by MedAvante ... a Johnson & Johnson company, submitted the NDA for ...
... privately-held biotechnology company focused on developing a novel class ... Quinton Oswald has joined the company as Chief Executive ... experience and management expertise to the CEO role. Most ... President & Business Unit Head for the Tissue Growth ...
Cached Medicine Technology:FDA Approves NDA That Includes Psychiatric Data Collected by Centralized Raters 2FDA Approves NDA That Includes Psychiatric Data Collected by Centralized Raters 3Quinton Oswald Named Chief Executive Officer of SARcode Corporation 2Quinton Oswald Named Chief Executive Officer of SARcode Corporation 3
1000 L, Racked, Pre-sterilized, 100 tips/rack Recommended for 500 and 1000 L pipettes....
300 L, Racked, Filtered, Pre-sterilized, 96 tips/rack Recommended for 250 and 300 L pipettes....
Diamond Filter Tips play a critical role in preventing aerosol-borne contamination. Also available sterilized (no need to autoclave) and certified free of detectable RNase, DNase, DNA, RNA, and prote...
... Eliminate aerosol contamination, which ... in PCR. Hydrophobic, nonwicking ... air can pass through ... in contrast to tips ...
Medicine Products: