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Let there be tissue-penetrating light: Scientists develop new nanoscale method to fight cancer
Date:2/28/2014

ton laser in the infrared red wavelength is 4 centimeters from the skin surface, this delivery system would work best for tumors within that range, which possibly include breast, stomach, colon and ovarian tumors, the researchers said.

In addition to their light sensitivity, the new nanoparticles are fluorescent and can be monitored in the body using molecular imaging techniques. This allows researchers to track the progress of the nanoparticle into the targeted cancer cell before light activation. The ability to track a targeted therapy in this way has been given the name "theranostics" a portmanteau of therapy and diagnostics in the scientific literature.

"We have a wonderful collaboration," Zink said. "When the Jonsson Comprehensive Cancer Center brings together totally diverse fields in this case, a physical chemist and a cell signaling scientist we can do things that neither one could do alone."

"Our collaboration with scientists at Charles Gerhardt Institute was important to the success of this two-photonactivated technique, which provides controls over drug delivery to allow local treatment that dramatically reduces side effects," said Tammanoi.


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Contact: Shaun Mason
smason@mednet.ucla.edu
310-206-2805
University of California - Los Angeles
Source:Eurekalert

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