Navigation Links
Let there be tissue-penetrating light: Scientists develop new nanoscale method to fight cancer
Date:2/28/2014

Researchers from UCLA's Jonsson Comprehensive Cancer Center have developed an innovative cancer-fighting technique in which custom-designed nanoparticles carry chemotherapy drugs directly to tumor cells and release their cargo when triggered by a two-photon laser in the infrared red wavelength.

The research findings by UCLA's Jeffrey Zink, a professor of chemistry and biochemistry, and Fuyu Tamanoi, a professor of microbiology, immunology and molecular genetics, and their colleagues were published online Feb. 20 in the journal Small and will appear in a later print edition.

Light-activated drug delivery holds promise for treating cancer because it give doctors control over precisely when and where in the body drugs are released. Delivering and releasing chemotherapy drugs so that they hit only tumor cells and not surrounding healthy tissues can greatly reduce treatment side effects and increase the drugs' cancer-killing effect. But the development of a drug-delivery system that responds to tissue-penetrating light has been a major challenge.

To address this, the teams of Tamanoi and Zink, which included scientists from the Jonsson Cancer Center's cancer nanotechnology and signal transduction and therapeutics programs, collaborated with Jean-Olivier Durand from France's University of Montpellier to develop a new type of nanoparticle that can absorb energy from tissue-penetrating light.

These new nanoparticles are equipped with thousands of pores, or tiny tubes, that can hold chemotherapy drugs. The ends of the pores are capped with nanovalves that keep the drugs in, like a cork in a bottle. The nanovalves contain special molecules that respond to energy from two-photon light exposure, which prompts the valves to open and release the drugs.

The operation of the nanoparticles was demonstrated in the laboratory using human breast cancer cells.

Because the effective range of the two-pho
'/>"/>

Contact: Shaun Mason
smason@mednet.ucla.edu
310-206-2805
University of California - Los Angeles
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Dr. Carol Francis Radio Talk Show Discusses Sexual Abuse as Related to "Coach" Jerry Sandusky; Interview With Abuse Survivor Teresa Joyce, Author of "There's A Fine Line"
2. New findings by GW researcher break tanning misconceptions: There is no such thing as a safe tan
3. Are there gender differences in anti-HIV drug efficacy?
4. Theres an app for that: Apple iPod Touch helps adults with autism function in the workplace
5. Youth with autism gravitate toward STEM majors in college -- if they get there
6. Are there racial disparities in osteoporosis screening and treatment?
7. Predicting risk of arrhythmias and sudden cardiac death: Theres a computer model for that
8. Is there a period of increased vulnerability for repeat traumatic brain injury?
9. Why are there redheads? Birds might hold the clues
10. When It Comes to Spine Surgery, There Is No July Effect: Study
11. Theres room for improvement in womens heart disease awareness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... (PRWEB) August 20, 2014 Blaine ... the innovative RevitaDERM® Psoriasis Treatment to ... associated with psoriasis. This all-in-one product was created ... RevitaDERM® Psoriasis Treatment is powered by coal tar ... associated with this effective ingredient. , RevitaDERM® ...
(Date:8/20/2014)... August 20, 2014 First Choice ... emergency rooms in the United States, named Richard Daniels, ... FM 685 facility. , “We are pleased to ... director of our second facility in Pflugerville,” said Dr. ... Emergency Room. , Dr. Daniels received his undergraduate ...
(Date:8/20/2014)... What to Do Now for UDI:, ... the Market, **FDAnews Webinar**, Sept. 11, 2014 — 1:30 ... Hospitals and other buyers of devices lose $5 billion ... systems. , Complying with the FDA’s deadlines is important, ... UDI as soon as possible. If devicemakers don’t, ...
(Date:8/19/2014)... Vancouver, WA (PRWEB) August 20, 2014 As ... school, and for themselves to return to the normal routine ... and snacks in tow, Kristen Yarker, MSc, RD encourages ... standard for their kids’ snack time. , Yarker explains, ... need for nutrients. Instead of giving them junk food handouts, ...
(Date:8/19/2014)... (PRWEB) August 20, 2014 What gives skin ... What can soften skin, replenish and nourish it while lightly ... Beauty®. , "Client after client raves about how their skin ... Heshelow, founder of Sublime Beauty®. "The ingredients are very ... use. Simply smooth it over cleansed skin of the ...
Breaking Medicine News(10 mins):Health News:RevitaDERM® Psoriasis Treatment Now Available At Over 7,600 CVS/pharmacies 2Health News:First Choice Emergency Room Announces Dr. Richard Daniels as Medical Director of the Pflugerville – FM 685 Facility 2Health News:FDAnews Announces — What to Do Now for UDI: Don’t Lose Your Customers by Getting Locked Out of the Market Webinar, Sept. 9, 2014 2Health News:FDAnews Announces — What to Do Now for UDI: Don’t Lose Your Customers by Getting Locked Out of the Market Webinar, Sept. 9, 2014 3Health News:FDAnews Announces — What to Do Now for UDI: Don’t Lose Your Customers by Getting Locked Out of the Market Webinar, Sept. 9, 2014 4Health News:Child Nutritionist Kristen Yarker Wants Parents to Rethink Kids’ Snacks This Fall 2Health News:Child Nutritionist Kristen Yarker Wants Parents to Rethink Kids’ Snacks This Fall 3Health News:That "Something Special" to Improve Skin Takes Only 10 Minutes Per Week; on Sale at Sublime Beauty® 2
... The cost of low health literacy the difference ... abilities to effectively communicate complex medical information is ... a leading biopharmaceutical company. To improve the health literacy ... offer a health literacy study emphasis beginning this fall. ...
... , ... Government Agencies to Increase ROI of IT Infrastructure , ... Reston, VA (PRWEB) February 18, 2010 -- Carahsoft ... Parabonâ Computation , a veteran provider of extreme-scale grid computing software and services. ...
... ... completed system-wide implementation of a software standardization program at seven hospital laboratories of ... ... , a leading provider of healthcare diagnostic information technology and outreach solutions, has ...
... rare thyroid tumor, but experts say effects in humans ... The U.S. Food and Drug Administration is defending its ... drug, Victoza (liraglutide), even though animal studies suggest it ... , Victoza, among a class of medicines called glucagon-like ...
... 2010) Van Andel Research Institute (VARI) researchers ... treatment that is currently the first line of defense against ... kidney cancer. Most patients who show a positive response ... year of treatment. Kidney cancer is among the 10 ...
... , ST. PETERS, Mo. , Feb. 18 ... Inc., has donated $25,000 to Meds & Food for ... to saving the lives of Haiti ,s malnourished children and ... peanut-based ready-to-use therapeutic food (RUTF) – known in Haiti ...
Cached Medicine News:Health News:MU offers training program to improve health literacy 2Health News:Parabon's Frontier Grid Platform Software Now Available on Carahsoft's GSA Schedule 2Health News:Parabon's Frontier Grid Platform Software Now Available on Carahsoft's GSA Schedule 3Health News:Sunquest Completes System-Wide Implementation at Cleveland Clinic Hospital Laboratories 2Health News:FDA Approved Diabetes Drug Despite Hints at Cancer Risk 2Health News:FDA Approved Diabetes Drug Despite Hints at Cancer Risk 3Health News:VARI findings may help patients with deadly kidney cancer 2Health News:MEMC Foundation Donates to Help Fight Malnourishment in Haiti 2Health News:MEMC Foundation Donates to Help Fight Malnourishment in Haiti 3
(Date:8/18/2014)... CAMBRIDGE, Mass. and HERZLIYA-PITUACH, Israel ... and NASDAQ OMX First North Premier, Stockholm ... received confirmation that its application to list its common stock ... NASDAQ Stock Market, a unit of the NASDAQ OMX Group. ... NASDAQ Capital Market at the opening of trading on August ...
(Date:8/18/2014)... , Aug. 18, 2014 Reportlinker.com ... is available in its catalogue: ... http://www.reportlinker.com/p01597713/Bioseparation-Systems-for-Global-Biopharmaceutical-Markets.html ... into three types: chromatography, membranes/filters and centrifuges. ... increasing and fueling growth of the global ...
(Date:8/18/2014)... Reportlinker.com announces that a new market ... Russia Bariatric Surgery Devices Market ... Russia Bariatric Surgery Devices Market ... GlobalData,s new report, "Russia Bariatric Surgery Devices ... on the Russia Bariatric Surgery Devices market. The ...
Breaking Medicine Technology:Immune Pharmaceuticals Announces Approval for Listing on the NASDAQ Capital Market 2Immune Pharmaceuticals Announces Approval for Listing on the NASDAQ Capital Market 3Immune Pharmaceuticals Announces Approval for Listing on the NASDAQ Capital Market 4Bioseparation Systems for Global Biopharmaceutical Markets 2Bioseparation Systems for Global Biopharmaceutical Markets 3Bioseparation Systems for Global Biopharmaceutical Markets 4Bioseparation Systems for Global Biopharmaceutical Markets 5Bioseparation Systems for Global Biopharmaceutical Markets 6Bioseparation Systems for Global Biopharmaceutical Markets 7Bioseparation Systems for Global Biopharmaceutical Markets 8Bioseparation Systems for Global Biopharmaceutical Markets 9Bioseparation Systems for Global Biopharmaceutical Markets 10Bioseparation Systems for Global Biopharmaceutical Markets 11Bioseparation Systems for Global Biopharmaceutical Markets 12Russia Bariatric Surgery Devices Market Outlook to 2020 2Russia Bariatric Surgery Devices Market Outlook to 2020 3Russia Bariatric Surgery Devices Market Outlook to 2020 4Russia Bariatric Surgery Devices Market Outlook to 2020 5
... The GoodKnight 420 CPAP System is the ... (CPAP) device on the market. It is ... preserve their lifestyles while complying with therapy. ... 600 sessions of date/time usage data. It ...
Micro-hematocrit tubes available in multiple sizes and additives for a wide range of capillary blood collection....
... VH IVUS technology uses advanced spectral ... of ultrasound images and provide detailed ... patient's atherosclerotic plaques. The colorized VH ... fibrous, fibro-fatty, dense calcium, and necrotic ...
... With the GE Innova 2100IQ: See the ... legs. Place interventional devices. Its all enabled ... panel that helps deliver excellent image quality ... Innova family systems installed worldwide, more physicians ...
Medicine Products: