Navigation Links
Let there be light
Date:5/23/2008

Researchers from the Peninsula Medical School in Cornwall, UK, have modified a photodynamic therapy (PDT) treatment that combines a topically applied cream with visible light to destroy cancer cells while leaving surrounding tissue unharmed.

The cream is applied directly to skin cancers and pre-cancers, which then naturally produces a photosensitive drug. A special red light is then shone on the tumour a few hours later, to activate this light sensitive compound. This results in cellular damage and the destruction of the tumour.

This technique results in reduced scarring and little or no damage to the surrounding healthy cells.

By adding the iron chelator CP94 to the cream, the research team have found that the effects of PDT are greatly improved and achieve greater reductions in tumour depth in tumours currently too thick to be treated easily by the non-enhanced form of this treatment.

This is the first time in the world that PDT trials of this modified PDT treatment have been carried out involving humans. Trials involving patients have taken place at clinics at the Royal Cornwall Hospitals NHS Trust in Truro.

PDT is achieving success in the treatment of actinic keratoses (lesions that can develop after years of exposure to UV light); Bowens disease (the growth of abnormal calls that can turn into skin cancer, and that is partly due to long-term exposure to the sun); and basal cell carcinoma (the most common form of skin cancer).

The work of the Peninsula Medical School in this area of research is funded in part by the Duchy Health Charity in Cornwall.

Dr. Alison Curnow from the Peninsula Medical School in Cornwall, commented: PDT is very effective non-surgical treatment for certain types of dermatological cancers and precancers. It normally destroys the tumour without scarring or damage to surrounding healthy cells.

She added: Through years of research we have been able to develop a modified PDT treatment enabling for the first time for thicker nodular basal cell carcinomas to be treated effectively with a single PDT treatment. This is important, as this is a very common form of skin cancer.

The work of Dr. Curnow and her team are part of a developing research theme for the Peninsula Medical School, which is Environment and Human Health. Operated mainly from the Peninsula Medical School in Cornwall, but with collaboration from colleagues within the institution across the South West of England, this research theme seeks to identify and study the links between our health and well-being and the environment.

More information is available by logging on at www.pms.ac.uk.

Care Study

Graham ONeill, 54, is technical marketing director at Imerys Minerals in Cornwall and lives near Mevagissey.

Graham was raised in the West Indies, and although his mother was very careful about protecting him from the sun, his exposure to the suns rays at an early age led to the discovery of melanomas on his skin in 1983.

Back then the treatments were quite severe, said Graham. It involved liquid nitrogen, scraping out the melanoma and cauterizing it. Not only was this very painful, but it also left scarring.

He now receives treatment with PDT, which is much better for him. He said: The treatment is extremely good. From a personal point of view it is much less unpleasant and seems to be more effective. It also treats quite a big area in one go, which means fewer treatments in the long run. The other issue with melanomas is that they keep coming back. With PDT I have found that they do not return as frequently and, when they do, they are far less severe.

On balance Graham is delighted with the treatments, which he has been receiving at Treliske Hospital, Royal Cornwall Hospitals NHS Trust in Truro. He said: Compared with the old way of doing things, PDT is a fantastic therapy and one which I would recommend to other patients. It is very exciting that the Peninsula Medical School is taking such a worldwide lead in research in this area.


'/>"/>

Contact: Andrew Gould
media@pr-works.co.uk
44-139-268-6107
The Peninsula College of Medicine and Dentistry
Source:Eurekalert

Related medicine news :

1. Experts Agree There is No Scientific Evidence of Health Risks in New Jersey Synthetic Turf Fields
2. Pelosi on Global HIV/AIDS Bill: There is a Moral Imperative to Combat This Epidemic
3. Is there a developmental component to the risk for depression?
4. Theres More Than Turkey Behind Holiday Yawns
5. Spectranetics Receives Reimbursement Approval in Belgium for Lead Removal and Peripheral Atherectomy Products
6. Young Twin Cities Boy Shows There is Life After Cancer
7. Is there really a mommy gene in women?
8. CIGNA Group Insurance Shows Consumers Theres More to Life Through a New Consumer Education Toolkit
9. At the synapse: Gene may shed light on neurological disorders
10. National Ad Campaign Highlights Patient Ratings For More Than 1,000 Local U.S. Hospitals
11. U.S. Turns Spotlight on Medicines Most Puzzling Cases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/28/2017)... ... June 28, 2017 , ... Eating disorders have the highest mortality rate of ... one person dies as a direct result from an eating disorder in the U.S. ... providers. The iaedp Foundation meets this challenge by offering what has become the leading ...
(Date:6/28/2017)... ... June 28, 2017 , ... Park Systems , ... Luncheon for all SEMICONWest attendees and Park customers on July 11, 2017 ... from Dr. Sang-il Park, Chairman & CEO of Park Systems, and Prof. Krishna ...
(Date:6/28/2017)... (PRWEB) , ... June 28, 2017 , ... ... assistance and financial consultations to communities in northern Virginia and DC, is announcing ... help provide for patients with Alzheimer’s and other disorders that lead to memory ...
(Date:6/27/2017)... PA and London UK (PRWEB) , ... June 27, 2017 , ... ... applying to a clinical study is whether they can trust the sponsor to pay ... it is vital that sponsors and CROs establish payment strategies that encourage sites to ...
(Date:6/27/2017)... ... 27, 2017 , ... Building on the success of the ... sixth state to pass legislation which ensures that children can possess and use ... the states of Alabama, Arizona, Florida, Utah and Washington who have also approved ...
Breaking Medicine News(10 mins):
(Date:6/13/2017)... Ind. , June 13, 2017 Zimmer Biomet ... musculoskeletal healthcare, today announced that the U.S. Food and Drug ... dated June 3, 2015 relating to its Zhejiang, ... "The successful clearance of the ... manufacturing facility is a measure of the progress ...
(Date:6/10/2017)... June 9, 2017  Shane K. Burchfield, DPM, is recognized by ... as a Podiatrist in Alabama . ... First Foot Care. He brings over 20 years of experience, as ... and healthcare, to his role. ... PC is pleased to welcome you to his practice," ...
(Date:6/8/2017)... 8, 2017  Less than a month ago, amateur ... 200,000 companies, including hospital networks, in over 150 countries. ... of the largest online extortion attempts ever recorded. With ... it is imperative that providers understand where the risks ... this — and many other very real cyber threats.  ...
Breaking Medicine Technology: