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Lessons from major heart trial need implementation
Date:5/10/2011

NEW YORK (May 10, 2011) -- A NewYork-Presbyterian Hospital/Weill Cornell Medical Center review of almost 500,000 cardiac cases nationally shows that the clinically indicated medical therapy reported in a widely publicized study was lost in translation to real-world heart care after its publication.

The researchers report in the May 11 issue of JAMA, the Journal of the American Medical Association, that medical therapy given to patients who received a heart stent improved less than 3 percent as a result of the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) trial. Overall, fewer than half of all patients received appropriate treatment with the combination of common cardiac drugs used in the COURAGE trial, such as aspirin, before their stenting procedure, and almost one-third didn't receive these drugs afterward.

As we all think about health care for the future, this study provides actionable information for both physicians and policymakers about quality of care and how comparative effectiveness research findings are being implemented, the researchers say.

"We find that an expensive and highly publicized clinical trial had a very limited effect on the clinical practice of providing optimal medical therapy, and this snapshot of what is happening in the real world should be a call for physicians, as well as policymakers, to look at how patient care can be improved," says the study's lead author, Dr. William Borden, assistant professor of medicine and of public health and the Nanette Laitman Clinical Scholar in Public Health at Weill Cornell Medical College, and a cardiologist at the Ronald O. Perelman Heart Institute of NewYork-Presbyterian Hospital/Weill Cornell Medical Center.

"These findings also should encourage patients to be aware of the need for optimal medical therapy if they are slated to receive a heart stent -- a consideration they should discuss with the physicians who
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Contact: Andrew Klein
ank2017@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

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